Class information for:
Level 1: NEDD8//COP9 SIGNALOSOME//NEDDYLATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9078 1190 47.6 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
204 3       PROTEASOME//UBIQUITIN//UNFOLDED PROTEIN RESPONSE 52492
677 2             PROTEASOME//UBIQUITIN//PROTEASOME INHIBITOR 13186
9078 1                   NEDD8//COP9 SIGNALOSOME//NEDDYLATION 1190

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEDD8 authKW 1687763 8% 67% 98
2 COP9 SIGNALOSOME authKW 1642103 7% 80% 80
3 NEDDYLATION authKW 1011049 5% 73% 54
4 CULLIN authKW 828770 5% 52% 62
5 JAB1 authKW 772802 4% 60% 50
6 MLN4924 authKW 649797 3% 77% 33
7 CSN5 authKW 346379 2% 75% 18
8 CUL4A authKW 319389 2% 66% 19
9 DENEDDYLATION authKW 307900 1% 100% 12
10 CULLIN RING LIGASE authKW 295821 1% 82% 14

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 7414 41% 0% 483
2 Biochemistry & Molecular Biology 4207 50% 0% 591
3 Oncology 1339 19% 0% 225
4 Genetics & Heredity 483 10% 0% 115
5 Developmental Biology 475 4% 0% 52
6 Biophysics 431 8% 0% 94
7 Plant Sciences 64 5% 0% 58
8 Pathology 63 3% 0% 33
9 Biochemical Research Methods 37 3% 0% 34
10 Mycology 9 1% 0% 6

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEALE SCI 106908 0% 83% 5
2 PROT UBIQUITYLAT UNIT 102633 0% 100% 4
3 RADIAT CANC BIOL 68593 3% 8% 33
4 EXPT TERATOLMINIST EDUC 49750 1% 24% 8
5 SCOTTISH CELL SIGNALLING 37726 0% 29% 5
6 ABT ENTWICKLUNGSGENET 34210 0% 67% 2
7 MOL CH ERONE BIOL 34210 0% 67% 2
8 PULM ASTHMA CYST FIBROSIS SLEEP 34210 0% 67% 2
9 SCOTTISH CELL SIGNALLING SCILLS 34210 0% 67% 2
10 STRUCT BIOL GENET TUMOR CELL BIOL 34210 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL DIVISION 15050 1% 5% 11
2 MOLECULAR CELL 4189 3% 1% 30
3 PLANT CELL 1864 2% 0% 21
4 BMC BIOCHEMISTRY 1782 0% 1% 5
5 EMBO REPORTS 1416 1% 1% 11
6 JOURNAL OF BIOLOGICAL CHEMISTRY 1165 7% 0% 87
7 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 1145 1% 0% 15
8 GENES & DEVELOPMENT 1087 2% 0% 18
9 ONCOTARGET 976 2% 0% 22
10 ONCOGENE 919 2% 0% 26

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NEDD8 1687763 8% 67% 98 Search NEDD8 Search NEDD8
2 COP9 SIGNALOSOME 1642103 7% 80% 80 Search COP9+SIGNALOSOME Search COP9+SIGNALOSOME
3 NEDDYLATION 1011049 5% 73% 54 Search NEDDYLATION Search NEDDYLATION
4 CULLIN 828770 5% 52% 62 Search CULLIN Search CULLIN
5 JAB1 772802 4% 60% 50 Search JAB1 Search JAB1
6 MLN4924 649797 3% 77% 33 Search MLN4924 Search MLN4924
7 CSN5 346379 2% 75% 18 Search CSN5 Search CSN5
8 CUL4A 319389 2% 66% 19 Search CUL4A Search CUL4A
9 DENEDDYLATION 307900 1% 100% 12 Search DENEDDYLATION Search DENEDDYLATION
10 CULLIN RING LIGASE 295821 1% 82% 14 Search CULLIN+RING+LIGASE Search CULLIN+RING+LIGASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ENCHEV, RI , SCHULMAN, BA , PETER, M , (2015) PROTEIN NEDDYLATION: BEYOND CULLIN-RING LIGASES.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 16. ISSUE 1. P. 30 -44 104 59% 46
2 MERGNER, J , SCHWECHHEIMER, C , (2014) THE NEDD8 MODIFICATION PATHWAY IN PLANTS.FRONTIERS IN PLANT SCIENCE. VOL. 5. ISSUE . P. - 115 65% 8
3 KATO, JY , YONEDA-KATO, N , (2009) MAMMALIAN COP9 SIGNALOSOME.GENES TO CELLS. VOL. 14. ISSUE 11. P. 1209 -1225 110 65% 68
4 DUBIEL, D , ROCKEL, B , NAUMANN, M , DUBIEL, W , (2015) DIVERSITY OF COP9 SIGNALOSOME STRUCTURES AND FUNCTIONAL CONSEQUENCES.FEBS LETTERS. VOL. 589. ISSUE 19. P. 2507 -2513 75 86% 6
5 ABIDI, N , XIRODIMAS, DP , (2015) REGULATION OF CANCER-RELATED PATHWAYS BY PROTEIN NEDDYLATION AND STRATEGIES FOR THE USE OF NEDD8 INHIBITORS IN THE CLINIC.ENDOCRINE-RELATED CANCER. VOL. 22. ISSUE 1. P. T55 -T70 108 62% 3
6 RABUT, G , PETER, M , (2008) FUNCTION AND REGULATION OF PROTEIN NEDDYLATION - 'PROTEIN MODIFICATIONS: BEYOND THE USUAL SUSPECTS' REVIEW SERIES.EMBO REPORTS. VOL. 9. ISSUE 10. P. 969-976 76 81% 141
7 ZHAO, YC , MORGAN, MA , SUN, Y , (2014) TARGETING NEDDYLATION PATHWAYS TO INACTIVATE CULLIN-RING LIGASES FOR ANTICANCER THERAPY.ANTIOXIDANTS & REDOX SIGNALING. VOL. 21. ISSUE 17. P. 2383 -2400 98 61% 15
8 WEI, N , SERINO, G , DENG, XW , (2008) THE COP9 SIGNALOSOME: MORE THAN A PROTEASE.TRENDS IN BIOCHEMICAL SCIENCES. VOL. 33. ISSUE 12. P. 592 -600 66 78% 191
9 TANAKA, T , NAKATANI, T , KAMITANI, T , (2013) NEGATIVE REGULATION OF NEDD8 CONJUGATION PATHWAY BY NOVEL MOLECULES AND AGENTS FOR ANTICANCER THERAPY.CURRENT PHARMACEUTICAL DESIGN. VOL. 19. ISSUE 22. P. 4131-4139 88 67% 9
10 BOSU, DR , KIPREOS, ET , (2008) CULLIN-RING UBIQUITIN LIGASES: GLOBAL REGULATION AND ACTIVATION CYCLES.CELL DIVISION. VOL. 3. ISSUE . P. - 79 65% 146

Classes with closest relation at Level 1


Rank Class id link
1 19492 FBXW7//FBW7//FBXO7
2 34066 MULIBREY NANISM//3 M SYNDROME//TRIM37
3 19896 U BOX//RING H2//SAUL1
4 3837 DEUBIQUITINATING ENZYME//UBIQUITIN//DEUBIQUITINASE
5 5545 SKP2//P27KIP1//P27
6 35756 UFM1//UBA5//UBE1DC1
7 32453 CXCL14//DBC2//BRAK
8 8269 UBIQUITIN//POLYUBIQUITIN GENE//UBIQUITIN CONJUGATING ENZYME
9 3923 SUMO//SUMOYLATION//UBC9
10 24159 FAT10//MALLORY BODIES//MALLORY DENK BODIES MDBS

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