Class information for:
Level 2: ACUTE PROMYELOCYTIC LEUKEMIA//ARSENIC TRIOXIDE//SUMO

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1843 6139 44.0 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
51 3       HEMATOLOGY//BONE MARROW TRANSPLANTATION//BLOOD 91443
1843 2             ACUTE PROMYELOCYTIC LEUKEMIA//ARSENIC TRIOXIDE//SUMO 6139
2558 1                   ACUTE PROMYELOCYTIC LEUKEMIA//ALL TRANS RETINOIC ACID//APL 2208
3923 1                   SUMO//SUMOYLATION//UBC9 1880
10209 1                   ARSENIC TRIOXIDE//AS2O3//ARSENIC TRIOXIDE AS2O3 1081
16854 1                   DAXX//PML//PML NUCLEAR BODIES 632
23684 1                   HIPK2//SIAH2//SIAH1 338

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ACUTE PROMYELOCYTIC LEUKEMIA authKW 2105536 10% 66% 637
2 ARSENIC TRIOXIDE authKW 2028808 10% 66% 623
3 SUMO authKW 949502 5% 57% 336
4 SUMOYLATION authKW 682078 5% 48% 286
5 APL authKW 454715 3% 56% 164
6 ALL TRANS RETINOIC ACID authKW 412120 5% 26% 320
7 PML RAR ALPHA authKW 371243 2% 77% 97
8 ACUTE PROMYELOCYTIC LEUKAEMIA authKW 359660 2% 72% 101
9 UBC9 authKW 325058 2% 65% 101
10 PML authKW 273037 3% 31% 177

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Hematology 36523 24% 1% 1466
2 Oncology 17791 29% 0% 1773
3 Cell Biology 12459 24% 0% 1484
4 Biochemistry & Molecular Biology 6354 29% 0% 1805
5 Genetics & Heredity 1490 8% 0% 481
6 Biophysics 390 4% 0% 247
7 Medicine, Research & Experimental 234 4% 0% 217
8 Developmental Biology 98 1% 0% 73
9 Virology 97 1% 0% 92
10 Toxicology 68 2% 0% 112

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SHANGHAI HEMATOL 84271 1% 23% 73
2 UMR 7212 54134 0% 78% 14
3 NEW FRONTIER SCI 42360 0% 61% 14
4 CELLULAR SENESCENCE GRP 35789 0% 60% 12
5 MOL ONCOGENESIS 28391 1% 18% 31
6 GLOBAL INITIAT PULSED POWER ENGN 27067 0% 78% 7
7 HUMAN GENETSLOAN KETTERING 24860 0% 100% 5
8 IST MED INTERNA SCI ONCOL 21681 0% 36% 12
9 CNRSUPR 9051 19888 0% 100% 4
10 UMR 944 19884 0% 67% 6

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LEUKEMIA 33383 4% 3% 226
2 BLOOD 13602 5% 1% 311
3 LEUKEMIA RESEARCH 10518 2% 2% 114
4 ONCOGENE 6462 3% 1% 156
5 LEUKEMIA & LYMPHOMA 6386 2% 1% 100
6 CANCER GENETICS AND CYTOGENETICS 6028 1% 1% 87
7 BRITISH JOURNAL OF HAEMATOLOGY 4863 2% 1% 117
8 BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY 4598 0% 3% 28
9 MOLECULAR CELL 3507 1% 1% 63
10 INTERNATIONAL JOURNAL OF HEMATOLOGY 2476 1% 1% 44

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ACUTE PROMYELOCYTIC LEUKEMIA 2105536 10% 66% 637 Search ACUTE+PROMYELOCYTIC+LEUKEMIA Search ACUTE+PROMYELOCYTIC+LEUKEMIA
2 ARSENIC TRIOXIDE 2028808 10% 66% 623 Search ARSENIC+TRIOXIDE Search ARSENIC+TRIOXIDE
3 SUMO 949502 5% 57% 336 Search SUMO Search SUMO
4 SUMOYLATION 682078 5% 48% 286 Search SUMOYLATION Search SUMOYLATION
5 APL 454715 3% 56% 164 Search APL Search APL
6 ALL TRANS RETINOIC ACID 412120 5% 26% 320 Search ALL+TRANS+RETINOIC+ACID Search ALL+TRANS+RETINOIC+ACID
7 PML RAR ALPHA 371243 2% 77% 97 Search PML+RAR+ALPHA Search PML+RAR+ALPHA
8 ACUTE PROMYELOCYTIC LEUKAEMIA 359660 2% 72% 101 Search ACUTE+PROMYELOCYTIC+LEUKAEMIA Search ACUTE+PROMYELOCYTIC+LEUKAEMIA
9 UBC9 325058 2% 65% 101 Search UBC9 Search UBC9
10 PML 273037 3% 31% 177 Search PML Search PML

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 FLOTHO, A , MELCHIOR, F , (2013) SUMOYLATION: A REGULATORY PROTEIN MODIFICATION IN HEALTH AND DISEASE.ANNUAL REVIEW OF BIOCHEMISTRY, VOL 82. VOL. 82. ISSUE . P. 357 -385 171 79% 184
2 JOHNSON, ES , (2004) PROTEIN MODIFICATION BY SUMO.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 73. ISSUE . P. 355-382 158 81% 974
3 GEISS-FRIEDLANDER, R , MELCHIOR, F , (2007) CONCEPTS IN SUMOYLATION: A DECADE ON.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 8. ISSUE 12. P. 947 -956 118 87% 813
4 DROESCHER, M , CHAUGULE, VK , PICHLER, A , (2013) SUMO RULES: REGULATORY CONCEPTS AND THEIR IMPLICATION IN NEUROLOGIC FUNCTIONS.NEUROMOLECULAR MEDICINE. VOL. 15. ISSUE 4. P. 639-660 213 81% 8
5 GAREAU, JR , LIMA, CD , (2010) THE SUMO PATHWAY: EMERGING MECHANISMS THAT SHAPE SPECIFICITY, CONJUGATION AND RECOGNITION.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 11. ISSUE 12. P. 861 -871 114 86% 366
6 WILKINSON, KA , HENLEY, JM , (2010) MECHANISMS, REGULATION AND CONSEQUENCES OF PROTEIN SUMOYLATION.BIOCHEMICAL JOURNAL. VOL. 428. ISSUE . P. 133-145 130 81% 209
7 BETTERMANN, K , BENESCH, M , WEIS, S , HAYBAECK, J , (2012) SUMOYLATION IN CARCINOGENESIS.CANCER LETTERS. VOL. 316. ISSUE 2. P. 113-125 161 71% 64
8 DOHMEN, RJ , (2004) SUMO PROTEIN MODIFICATION.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. VOL. 1695. ISSUE 1-3. P. 113-131 172 80% 131
9 CHAN, HY , LAM, WL , LAM, KH , LAM, LSM , NG, TB , AU, SWN , XU, Z , (2009) SUMO PROTEASES: REDOX REGULATION AND BIOLOGICAL CONSEQUENCES.ANTIOXIDANTS & REDOX SIGNALING. VOL. 11. ISSUE 6. P. 1453 -1484 208 66% 13
10 DE THE, H , CHEN, Z , (2010) ACUTE PROMYELOCYTIC LEUKAEMIA: NOVEL INSIGHTS INTO THE MECHANISMS OF CURE.NATURE REVIEWS CANCER. VOL. 10. ISSUE 11. P. 775 -783 117 82% 154

Classes with closest relation at Level 2


Rank Class id link
1 3161 GRANULOCYTIC SARCOMA//CHLOROMA//MYELOID SARCOMA
2 2713 METHYLSULFONYLMETHANE//SEROFENDIC ACID//N ACETYL S N METHYLCARBAMOYLCYSTEINE
3 613 VITAMIN A//RETINOIDS//RETINOIC ACID
4 677 PROTEASOME//UBIQUITIN//PROTEASOME INHIBITOR
5 56 MYELODYSPLASTIC SYNDROME//HEMATOLOGY//ACUTE MYELOID LEUKEMIA
6 467 ARSENIC//ARSENITE//ARSENIC SPECIATION
7 1216 PU1//ETS 1//GATA 1
8 3084 CHROMOSOME TERRITORY//NUCLEAR ARCHITECTURE//NUCLEAR ORGANIZATION
9 3037 KLF4//KRUPPEL LIKE FACTOR//GADD45
10 1531 HISTONE DEACETYLASE INHIBITOR//HISTONE DEACETYLASE//HDAC INHIBITOR

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