Class information for:
Level 2: KLF4//KRUPPEL LIKE FACTOR//GADD45

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3037 2468 43.8 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
204 3       PROTEASOME//UBIQUITIN//UNFOLDED PROTEIN RESPONSE 52492
3037 2             KLF4//KRUPPEL LIKE FACTOR//GADD45 2468
8864 1                   KLF4//KRUPPEL LIKE FACTOR//KLF5 1210
15722 1                   MITHRAMYCIN//SP1//TOLFENAMIC ACID 696
19975 1                   GADD45//GADD45A//GADD45 ALPHA 482
36462 1                   ZBP 89//ZNF148//BAK GENES 80

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 KLF4 authKW 654440 4% 53% 100
2 KRUPPEL LIKE FACTOR authKW 528328 3% 69% 62
3 GADD45 authKW 385568 3% 47% 67
4 KLF5 authKW 379338 2% 67% 46
5 KRUPPEL LIKE FACTOR 4 authKW 379338 2% 67% 46
6 KLF6 authKW 333991 1% 75% 36
7 MITHRAMYCIN authKW 214334 1% 47% 37
8 KRUPPEL LIKE FACTOR 6 authKW 200402 1% 90% 18
9 KLF10 authKW 182180 1% 82% 18
10 SP1 authKW 168789 5% 10% 131

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 5664 41% 0% 1014
2 Cell Biology 4998 24% 0% 596
3 Oncology 4299 23% 0% 566
4 Genetics & Heredity 997 10% 0% 238
5 Biophysics 504 6% 0% 154
6 Developmental Biology 436 3% 0% 75
7 Medicine, Research & Experimental 174 4% 0% 107
8 Hematology 138 3% 0% 77
9 Endocrinology & Metabolism 94 4% 0% 91
10 Gastroenterology & Hepatology 91 3% 0% 66

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENE PONSE SECT 89359 1% 43% 17
2 CASE CARDIOVASC 51788 1% 25% 17
3 EPIGENET CHROMATIN DYNAM 41794 1% 26% 13
4 TRANSLAT ANIM 37112 0% 100% 3
5 TRANSLAT EPIGENET REPROD 32986 0% 67% 4
6 VET PHYSIOL PHARMACOL 24971 2% 5% 43
7 B9 24741 0% 100% 2
8 CHICKEN GENET BREEDINGMINIST AGR 24741 0% 100% 2
9 EPIGENET TRANSLAT PROGRAM IN IDUALIZED MED 24741 0% 100% 2
10 HANG ZHOU HOSP TRADIT CHINESE MED 24741 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOGENE 4603 3% 0% 83
2 JOURNAL OF BIOLOGICAL CHEMISTRY 3899 9% 0% 226
3 MOLECULAR AND CELLULAR BIOLOGY 1715 2% 0% 57
4 CANCER RESEARCH 1044 2% 0% 60
5 MECHANISMS OF DEVELOPMENT 987 1% 1% 16
6 ONCOTARGET 916 1% 0% 31
7 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 786 3% 0% 70
8 TUMOR BIOLOGY 770 1% 0% 20
9 MOLECULAR CANCER THERAPEUTICS 749 1% 0% 16
10 NUCLEIC ACIDS RESEARCH 669 2% 0% 49

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 KLF4 654440 4% 53% 100 Search KLF4 Search KLF4
2 KRUPPEL LIKE FACTOR 528328 3% 69% 62 Search KRUPPEL+LIKE+FACTOR Search KRUPPEL+LIKE+FACTOR
3 GADD45 385568 3% 47% 67 Search GADD45 Search GADD45
4 KLF5 379338 2% 67% 46 Search KLF5 Search KLF5
5 KRUPPEL LIKE FACTOR 4 379338 2% 67% 46 Search KRUPPEL+LIKE+FACTOR+4 Search KRUPPEL+LIKE+FACTOR+4
6 KLF6 333991 1% 75% 36 Search KLF6 Search KLF6
7 MITHRAMYCIN 214334 1% 47% 37 Search MITHRAMYCIN Search MITHRAMYCIN
8 KRUPPEL LIKE FACTOR 6 200402 1% 90% 18 Search KRUPPEL+LIKE+FACTOR+6 Search KRUPPEL+LIKE+FACTOR+6
9 KLF10 182180 1% 82% 18 Search KLF10 Search KLF10
10 SP1 168789 5% 10% 131 Search SP1 Search SP1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MCCONNELL, BB , YANG, VW , (2010) MAMMALIAN KRUPPEL-LIKE FACTORS IN HEALTH AND DISEASES.PHYSIOLOGICAL REVIEWS. VOL. 90. ISSUE 4. P. 1337 -1381 322 65% 265
2 TETREAULT, MP , YANG, YZ , KATZ, JP , (2013) KRUPPEL-LIKE FACTORS IN CANCER.NATURE REVIEWS CANCER. VOL. 13. ISSUE 10. P. 701-713 147 78% 54
3 VIZCAINO, C , MANSILLA, S , PORTUGAL, J , (2015) SP1 TRANSCRIPTION FACTOR: A LONG-STANDING TARGET IN CANCER CHEMOTHERAPY.PHARMACOLOGY & THERAPEUTICS. VOL. 152. ISSUE . P. 111 -124 105 61% 17
4 HASHMI, S , WANG, Y , SUMAN, DS , PARHAR, RS , COLLISON, K , CONCA, W , AL-MOHANNA, F , GAUGLER, R , (2015) HUMAN CANCER: IS IT LINKED TO DYSFUNCTIONAL LIPID METABOLISM?.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. VOL. 1850. ISSUE 2. P. 352 -364 119 65% 3
5 BUREAU, C , HANOUN, N , TORRISANI, J , VINEL, JP , BUSCAIL, L , CORDELIER, P , (2009) EXPRESSION AND FUNCTION OF KRUPPEL LIKE-FACTORS (KLF) IN CARCINOGENESIS.CURRENT GENOMICS. VOL. 10. ISSUE 5. P. 353-360 97 87% 38
6 PARK, CS , SHEN, Y , LEWIS, A , LACORAZZA, HD , (2016) ROLE OF THE REPROGRAMMING FACTOR KLF4 IN BLOOD FORMATION.JOURNAL OF LEUKOCYTE BIOLOGY. VOL. 99. ISSUE 5. P. 673 -685 106 65% 2
7 DIAKIW, SM , D'ANDREA, RJ , BROWN, AL , (2013) THE DOUBLE LIFE OF KLF5: OPPOSING ROLES IN REGULATION OF GENE-EXPRESSION, CELLULAR FUNCTION, AND TRANSFORMATION.IUBMB LIFE. VOL. 65. ISSUE 12. P. 999 -1011 87 81% 8
8 DONG, JT , CHEN, CS , (2009) ESSENTIAL ROLE OF KLF5 TRANSCRIPTION FACTOR IN CELL PROLIFERATION AND DIFFERENTIATION AND ITS IMPLICATIONS FOR HUMAN DISEASES.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 66. ISSUE 16. P. 2691 -2706 90 67% 68
9 GAO, Y , DING, Y , CHEN, HY , CHEN, HJ , ZHOU, J , (2015) TARGETING KRUPPEL-LIKE FACTOR 5 (KLF5) FOR CANCER THERAPY.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 15. ISSUE 8. P. 699 -713 84 68% 3
10 EVANS, PM , LIU, CM , (2008) ROLES OF KRUPPEL-LIKE FACTOR 4 IN NORMAL HOMEOSTASIS, CANCER AND STEM CELLS.ACTA BIOCHIMICA ET BIOPHYSICA SINICA. VOL. 40. ISSUE 7. P. 554 -564 82 69% 85

Classes with closest relation at Level 2


Rank Class id link
1 3833 CITED2//BRANCHIO OCULO FACIAL SYNDROME//AP 2 ALPHA
2 1216 PU1//ETS 1//GATA 1
3 3893 PRL 3//ATF3//ATF5
4 2636 COILED COIL//KRAB DOMAIN//PROTEIN DESIGN
5 2641 EPITHELIAL MESENCHYMAL TRANSITION//EMT//SNAIL
6 3713 A20//LAPTM4B//WWP1
7 1709 C FOS//EGR 1//IMMEDIATE EARLY GENE
8 3263 CTCF//CONTROL GENET PROC//NF Y
9 3108 FOXM1//FOXO1//FOXO
10 936 P53//MDM2//P73

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