Class information for:
Level 2: COILED COIL//KRAB DOMAIN//PROTEIN DESIGN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2636 3515 44.1 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
219 3       PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS//PROTEIN FOLDING//PROTEIN STRUCTURE PREDICTION 50409
2636 2             COILED COIL//KRAB DOMAIN//PROTEIN DESIGN 3515
5549 1                   COILED COIL//PROTEIN DESIGN//DE NOVO DESIGN 1607
14197 1                   ARTIFICIAL TRANSCRIPTION FACTOR//ZINC FINGER//RECOGNITION CODE 785
14264 1                   KRAB DOMAIN//KRAB//SCAN DOMAIN 781
27495 1                   UM SYLVESTER BRAMAN FAMILY BREAST CANC//GCN4P//DNA PROMOTER ELEMENTS TRE AND CRE 228
34246 1                   E2A HLF//DRS GENE//HEPATIC LEUKEMIA FACTOR 114

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 COILED COIL authKW 347098 5% 23% 174
2 KRAB DOMAIN authKW 260559 1% 100% 30
3 PROTEIN DESIGN authKW 224532 4% 17% 151
4 ZINC FINGER authKW 216602 5% 15% 162
5 ARTIFICIAL TRANSCRIPTION FACTOR authKW 185460 1% 69% 31
6 KRAB authKW 172500 1% 83% 24
7 DE NOVO DESIGN authKW 163726 2% 29% 65
8 ZINC FINGER PROTEIN authKW 147872 2% 20% 86
9 FOUR HELIX BUNDLE authKW 123810 1% 39% 37
10 LEUCINE ZIPPER authKW 112726 2% 18% 71

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 17132 57% 0% 2016
2 Biophysics 3794 13% 0% 448
3 Cell Biology 2153 14% 0% 504
4 Chemistry, Multidisciplinary 1300 15% 0% 529
5 Genetics & Heredity 1273 9% 0% 324
6 Biotechnology & Applied Microbiology 369 6% 0% 205
7 Biochemical Research Methods 364 4% 0% 153
8 Developmental Biology 122 2% 0% 55
9 Chemistry, Organic 111 4% 0% 151
10 Chemistry, Medicinal 61 2% 0% 72

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEART DEV 76423 1% 35% 25
2 JOHNSON FDN 68872 2% 13% 62
3 BIOL BIOCHEM 2 65125 0% 50% 15
4 ONCOGENESE 38684 0% 64% 7
5 BIOMOL DESIGN DRUG DEV 32827 0% 34% 11
6 POINT RICHMOND TECH 30895 0% 32% 11
7 BCH DORIGNY 30011 0% 31% 11
8 FRONTIERS GENET PROGRAM 29302 0% 38% 9
9 INTERUNIV BIOACT PEPTIDES CIRPEB 27138 0% 63% 5
10 FRONTIERS IN GENET COMPETENCE 26056 0% 100% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROTEIN SCIENCE 9643 2% 1% 84
2 FOLDING & DESIGN 9592 0% 8% 14
3 BIOCHEMISTRY 6582 6% 0% 205
4 JOURNAL OF MOLECULAR BIOLOGY 4507 3% 0% 112
5 PROTEIN ENGINEERING 4126 1% 1% 33
6 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 4098 6% 0% 216
7 BIOPOLYMERS 3810 2% 1% 54
8 CURRENT OPINION IN STRUCTURAL BIOLOGY 3382 1% 1% 30
9 GENOMICS 2049 1% 1% 45
10 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 1798 1% 1% 37

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 COILED COIL 347098 5% 23% 174 Search COILED+COIL Search COILED+COIL
2 KRAB DOMAIN 260559 1% 100% 30 Search KRAB+DOMAIN Search KRAB+DOMAIN
3 PROTEIN DESIGN 224532 4% 17% 151 Search PROTEIN+DESIGN Search PROTEIN+DESIGN
4 ZINC FINGER 216602 5% 15% 162 Search ZINC+FINGER Search ZINC+FINGER
5 ARTIFICIAL TRANSCRIPTION FACTOR 185460 1% 69% 31 Search ARTIFICIAL+TRANSCRIPTION+FACTOR Search ARTIFICIAL+TRANSCRIPTION+FACTOR
6 KRAB 172500 1% 83% 24 Search KRAB Search KRAB
7 DE NOVO DESIGN 163726 2% 29% 65 Search DE+NOVO+DESIGN Search DE+NOVO+DESIGN
8 ZINC FINGER PROTEIN 147872 2% 20% 86 Search ZINC+FINGER+PROTEIN Search ZINC+FINGER+PROTEIN
9 FOUR HELIX BUNDLE 123810 1% 39% 37 Search FOUR+HELIX+BUNDLE Search FOUR+HELIX+BUNDLE
10 LEUCINE ZIPPER 112726 2% 18% 71 Search LEUCINE+ZIPPER Search LEUCINE+ZIPPER

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 YU, FT , CANGELOSI, VM , ZASTROW, ML , TEGONI, M , PLEGARIA, JS , TEBO, AG , MOCNY, CS , RUCKTHONG, L , QAYYUM, H , PECORARO, VL , (2014) PROTEIN DESIGN: TOWARD FUNCTIONAL METALLOENZYMES.CHEMICAL REVIEWS. VOL. 114. ISSUE 7. P. 3495 -3578 261 29% 97
2 WOOLFSON, DN , (2005) THE DESIGN OF COILED-COIL STRUCTURES AND ASSEMBLIES.FIBROUS PROTEINS: COILED-COILS, COLLAGEN AND ELASTOMERS. VOL. 70. ISSUE . P. 79 -+ 92 76% 291
3 ZASTROW, ML , PECORARO, VL , (2013) DESIGNING FUNCTIONAL METALLOPROTEINS: FROM STRUCTURAL TO CATALYTIC METAL SITES.COORDINATION CHEMISTRY REVIEWS. VOL. 257. ISSUE 17-18. P. 2565-2588 104 53% 35
4 PAPWORTH, M , KOLASINSKA, P , MINCZUK, M , (2006) DESIGNER ZINC-FINGER PROTEINS AND THEIR APPLICATIONS.GENE. VOL. 366. ISSUE 1. P. 27 -38 86 75% 73
5 APOSTOLOVIC, B , DANIAL, M , KLOK, HA , (2010) COILED COILS: ATTRACTIVE PROTEIN FOLDING MOTIFS FOR THE FABRICATION OF SELF-ASSEMBLED, RESPONSIVE AND BIOACTIVE MATERIALS.CHEMICAL SOCIETY REVIEWS. VOL. 39. ISSUE 9. P. 3541 -3575 99 51% 102
6 WOLFE, SA , NEKLUDOVA, L , PABO, CO , (2000) DNA RECOGNITION BY CYS(2)HIS(2) ZINC FINGER PROTEINS.ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE. VOL. 29. ISSUE . P. 183-212 78 66% 483
7 MASON, JM , ARNDT, KM , (2004) COILED COIL DOMAINS: STABILITY, SPECIFICITY, AND BIOLOGICAL IMPLICATIONS.CHEMBIOCHEM. VOL. 5. ISSUE 2. P. 170 -176 60 82% 331
8 TAKEI, T , TSUMOTO, K , YOSHINO, M , KOJIMA, S , YAZAKI, K , UEDA, T , TAKEI, T , ARISAKA, F , MIURA, K , (2014) ROLE OF POSITIONS E AND G IN THE FIBROUS ASSEMBLY FORMATION OF AN AMPHIPATHIC ALPHA-HELIX-FORMING POLYPEPTIDE.BIOPOLYMERS. VOL. 102. ISSUE 3. P. 260-272 60 87% 0
9 PABO, CO , PEISACH, E , GRANT, RA , (2001) DESIGN AND SELECTION OF NOVEL CYS(2)HIS(2) ZINC FINGER PROTEINS.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 70. ISSUE . P. 313-340 80 62% 372
10 LUPO, A , CESARO, E , MONTANO, G , ZURLO, D , IZZO, P , COSTANZO, P , (2013) KRAB-ZINC FINGER PROTEINS: A REPRESSOR FAMILY DISPLAYING MULTIPLE BIOLOGICAL FUNCTIONS.CURRENT GENOMICS. VOL. 14. ISSUE 4. P. 268 -278 60 71% 36

Classes with closest relation at Level 2


Rank Class id link
1 365 PROTEIN STRUCTURE PREDICTION//PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS//PSEUDO AMINO ACID COMPOSITION
2 3037 KLF4//KRUPPEL LIKE FACTOR//GADD45
3 1709 C FOS//EGR 1//IMMEDIATE EARLY GENE
4 260 PROTEIN FOLDING//JOURNAL OF CHEMICAL THEORY AND COMPUTATION//JOURNAL OF COMPUTATIONAL CHEMISTRY
5 1200 PEPTAIBOL//FOLDAMERS//PEPTOIDS
6 2423 CATALYTIC ANTIBODIES//ABZYME//DIRECTED EVOLUTION
7 1115 GENOME EDITING//CRISPR CAS9//CRISPR
8 3833 CITED2//BRANCHIO OCULO FACIAL SYNDROME//AP 2 ALPHA
9 2154 PHAGE DISPLAY//FILAMENTOUS BACTERIOPHAGE//MIMOTOPE
10 2754 MYC//MAX//C MYC

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