Class information for:
Level 2: FGF21//FIBROBLAST GROWTH FACTOR//FIBROBLAST GROWTH FACTOR 21

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1927 5824 41.3 85%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
1927 2             FGF21//FIBROBLAST GROWTH FACTOR//FIBROBLAST GROWTH FACTOR 21 5824
642 1                   FIBROBLAST GROWTH FACTOR//BASIC FIBROBLAST GROWTH FACTOR//FGF RECEPTOR 3216
10558 1                   FGFR//FIBROBLAST GROWTH FACTOR RECEPTOR 4//FGFR4 1054
14626 1                   FGF21//FIBROBLAST GROWTH FACTOR 21//FGF 21 759
18138 1                   SURAMIN//HT 29 D4 CELLS//SURAMIN ANALOGS 564
33389 1                   PENTOSAN POLYSULFATE//ELMIRON//LASER ANIMAL MODEL 125
37489 1                   CA 2 SPIKING//DAMAGED AORTA//LAW INTERDISCIPLINE 56
37725 1                   FGF BP//FGF BINDING PROTEIN//HBP17 FGFBP 1 50

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FGF21 authKW 483430 2% 75% 123
2 FIBROBLAST GROWTH FACTOR authKW 410686 6% 21% 373
3 FIBROBLAST GROWTH FACTOR 21 authKW 362804 2% 77% 90
4 FIBROBLAST GROWTH FACTOR RECEPTOR authKW 310418 3% 39% 153
5 SURAMIN authKW 289866 3% 29% 191
6 BASIC FIBROBLAST GROWTH FACTOR authKW 220414 4% 16% 262
7 FGF RECEPTOR authKW 179774 2% 38% 90
8 FGFR authKW 141426 1% 34% 80
9 FGFR4 authKW 137787 1% 56% 47
10 FIBROBLAST GROWTH FACTOR RECEPTOR 4 authKW 125926 0% 83% 29

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Cell Biology 10451 23% 0% 1332
2 Oncology 8138 21% 0% 1211
3 Biochemistry & Molecular Biology 5566 28% 0% 1658
4 Endocrinology & Metabolism 3383 10% 0% 604
5 Biophysics 1091 6% 0% 351
6 Neurosciences 1003 10% 0% 591
7 Developmental Biology 838 3% 0% 162
8 CYTOLOGY & HISTOLOGY 356 0% 0% 24
9 Pathology 349 3% 0% 169
10 Physiology 272 3% 0% 198

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL STRUCT NEUROBIOL GENE THER Y PROGRAM 53657 0% 64% 16
2 CANC BIOL NUTR 44913 0% 32% 27
3 IBT PROTE NANOTECHNOL 26206 0% 100% 5
4 UNIT GEN PATHOL IMMUNOL 17488 0% 18% 19
5 WESTERN NEW YORK STEM CELLS CULTURE ANAL 15723 0% 100% 3
6 SIGNALING MOL 15098 0% 41% 7
7 ALBERT B ALKEK BIOSCI TECHNOL 13458 0% 21% 12
8 ENGN GENE MED 11906 0% 45% 5
9 SYST BIOMED TECHNOL 11169 0% 27% 8
10 CRUK EXCELLENCE 10482 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GROWTH FACTORS 11018 1% 5% 41
2 JOURNAL OF CELLULAR PHYSIOLOGY 4950 2% 1% 99
3 ONCOGENE 4335 2% 1% 125
4 MOLECULAR METABOLISM 3058 0% 4% 14
5 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2565 3% 0% 192
6 CANCER RESEARCH 2553 2% 0% 144
7 CELL METABOLISM 2206 0% 2% 25
8 CELL GROWTH & DIFFERENTIATION 1927 0% 2% 23
9 JOURNAL OF BIOLOGICAL CHEMISTRY 1810 4% 0% 252
10 IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY 1355 0% 2% 16

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FGF21 483430 2% 75% 123 Search FGF21 Search FGF21
2 FIBROBLAST GROWTH FACTOR 410686 6% 21% 373 Search FIBROBLAST+GROWTH+FACTOR Search FIBROBLAST+GROWTH+FACTOR
3 FIBROBLAST GROWTH FACTOR 21 362804 2% 77% 90 Search FIBROBLAST+GROWTH+FACTOR+21 Search FIBROBLAST+GROWTH+FACTOR+21
4 FIBROBLAST GROWTH FACTOR RECEPTOR 310418 3% 39% 153 Search FIBROBLAST+GROWTH+FACTOR+RECEPTOR Search FIBROBLAST+GROWTH+FACTOR+RECEPTOR
5 SURAMIN 289866 3% 29% 191 Search SURAMIN Search SURAMIN
6 BASIC FIBROBLAST GROWTH FACTOR 220414 4% 16% 262 Search BASIC+FIBROBLAST+GROWTH+FACTOR Search BASIC+FIBROBLAST+GROWTH+FACTOR
7 FGF RECEPTOR 179774 2% 38% 90 Search FGF+RECEPTOR Search FGF+RECEPTOR
8 FGFR 141426 1% 34% 80 Search FGFR Search FGFR
9 FGFR4 137787 1% 56% 47 Search FGFR4 Search FGFR4
10 FIBROBLAST GROWTH FACTOR RECEPTOR 4 125926 0% 83% 29 Search FIBROBLAST+GROWTH+FACTOR+RECEPTOR+4 Search FIBROBLAST+GROWTH+FACTOR+RECEPTOR+4

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BASILICO, C , MOSCATELLI, D , (1992) THE FGF FAMILY OF GROWTH-FACTORS AND ONCOGENES.ADVANCES IN CANCER RESEARCH. VOL. 59. ISSUE . P. 115-165 205 83% 971
2 FISHER, FM , MARATOS-FLIER, E , (2016) UNDERSTANDING THE PHYSIOLOGY OF FGF21.ANNUAL REVIEW OF PHYSIOLOGY, VOL 78. VOL. 78. ISSUE . P. 223 -241 102 94% 11
3 DEGIROLAMO, C , SABBA, C , MOSCHETTA, A , (2016) THERAPEUTIC POTENTIAL OF THE ENDOCRINE FIBROBLAST GROWTH FACTORS FGF19, FGF21 AND FGF23.NATURE REVIEWS DRUG DISCOVERY. VOL. 15. ISSUE 1. P. 51 -69 138 60% 13
4 POWERS, CJ , MCLESKEY, SW , WELLSTEIN, A , (2000) FIBROBLAST GROWTH FACTORS, THEIR RECEPTORS AND SIGNALING.ENDOCRINE-RELATED CANCER. VOL. 7. ISSUE 3. P. 165 -197 166 63% 827
5 BURGESS, WH , MACIAG, T , (1989) THE HEPARIN-BINDING (FIBROBLAST) GROWTH-FACTOR FAMILY OF PROTEINS.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 58. ISSUE . P. 575 -606 153 66% 1780
6 ORNITZ, DM , ITOH, N , (2015) THE FIBROBLAST GROWTH FACTOR SIGNALING PATHWAY.WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY. VOL. 4. ISSUE 3. P. 215 -266 216 31% 57
7 NIES, VJM , SANCAR, G , LIU, WL , VAN ZUTPHEN, T , STRUIK, D , YU, RT , ATKINS, AR , EVANS, RM , JONKER, JW , DOWNES, MR , (2016) FIBROBLAST GROWTH FACTOR SIGNALING IN METABOLIC REGULATION.FRONTIERS IN ENDOCRINOLOGY. VOL. 6. ISSUE . P. - 115 81% 2
8 ZHANG, J , LI, Y , (2015) FIBROBLAST GROWTH FACTOR 21 ANALOGS FOR TREATING METABOLIC DISORDERS.FRONTIERS IN ENDOCRINOLOGY. VOL. 6. ISSUE . P. - 101 95% 4
9 SO, WY , LEUNG, PS , (2016) FIBROBLAST GROWTH FACTOR 21 AS AN EMERGING THERAPEUTIC TARGET FOR TYPE 2 DIABETES MELLITUS.MEDICINAL RESEARCH REVIEWS. VOL. 36. ISSUE 4. P. 672 -704 129 72% 1
10 LI, XK , WANG, C , XIAO, J , MCKEEHAN, WL , WANG, F , (2016) FIBROBLAST GROWTH FACTORS, OLD KIDS ON THE NEW BLOCK.SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. VOL. 53. ISSUE . P. 155 -167 125 58% 5

Classes with closest relation at Level 2


Rank Class id link
1 3948 SPROUTY//LRIG1//MIG 6
2 794 PROTEOGLYCAN//HEPARANASE//HEPARAN SULFATE
3 2658 ACHONDROPLASIA//SKELETAL DYSPLASIA//HYPOCHONDROPLASIA
4 361 ANGIOGENESIS//ENDOSTATIN//VEGF
5 1648 EPIDERMAL GROWTH FACTOR//HB EGF//TRANSFORMING GROWTH FACTOR ALPHA
6 2498 CRANIOSYNOSTOSIS//PLAGIOCEPHALY//APERT SYNDROME
7 1197 PULMONARY SURFACTANT//SURFACTANT PROTEIN A//SURFACTANT PROTEIN D
8 1452 CHRONIC MYELOID LEUKEMIA//IMATINIB//NILOTINIB
9 1804 ARTERIOGENESIS//COLLATERAL CIRCULATION//TRANSMYOCARDIAL LASER REVASCULARIZATION
10 2111 KLOTHO//FIBROBLAST GROWTH FACTOR 23//HYPOPHOSPHATEMIA

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