Class information for:
Level 2: SPROUTY//LRIG1//MIG 6

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3948 759 39.0 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
3948 2             SPROUTY//LRIG1//MIG 6 759
23744 1                   SPROUTY//SPROUTY2//SPRED 336
27430 1                   LRIG1//LRIG3//UROFACIAL SYNDROME 230
29090 1                   MIG 6//ACK1//RALT 193

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SPROUTY authKW 1393124 8% 56% 62
2 LRIG1 authKW 1290913 5% 84% 38
3 MIG 6 authKW 764363 3% 100% 19
4 ACK1 authKW 643666 3% 80% 20
5 SPROUTY2 authKW 473274 3% 59% 20
6 RALT authKW 325858 1% 90% 9
7 LRIG authKW 321837 1% 100% 8
8 LRIG3 authKW 321837 1% 100% 8
9 UROFACIAL SYNDROME authKW 296233 1% 82% 9
10 SPRED authKW 268191 1% 67% 10

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 2340 29% 0% 222
2 Oncology 1496 24% 0% 184
3 Biochemistry & Molecular Biology 1436 38% 0% 287
4 Developmental Biology 1199 8% 0% 63
5 Genetics & Heredity 620 13% 0% 99
6 Biophysics 234 7% 0% 56
7 Medicine, Research & Experimental 59 4% 0% 34
8 Anatomy & Morphology 31 1% 0% 8
9 Urology & Nephrology 26 3% 0% 19
10 Pathology 22 2% 0% 17

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEW DRUG DEV DISCOVERY 80459 0% 100% 2
2 SINO GERMAN NEUROONCOL MOL 80459 0% 100% 2
3 UNIV HOSP SAN VINCENTE DE PAUL 80459 0% 100% 2
4 COOPERAT PROGRAM MOL GENET CELL BIOL 72411 0% 60% 3
5 CELLULAR BIOL NEUROSCI PROF DR E DE ROBERT 53638 0% 67% 2
6 SINOGERMAN NEUROONCOL MOL 53638 0% 67% 2
7 MOL CELLULAR IMMUNOL 42006 2% 7% 16
8 AFFILIATED HOSP XIANG YA MED 3 40230 0% 100% 1
9 AFFILIATED LISHUI HOSPAFFILIATED HOSP 5CENT HOS 40230 0% 100% 1
10 AFFILIATED TUMOR HOSP XIANGYA MED 40230 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENE EXPRESSION PATTERNS 2572 1% 1% 8
2 ONCOGENE 2101 4% 0% 31
3 JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES 1563 1% 0% 8
4 MOLECULAR CANCER RESEARCH 1044 1% 0% 7
5 JOURNAL OF BIOLOGICAL CHEMISTRY 1007 8% 0% 64
6 NATO ADVANCED SCIENCE INSTITUTES SERIES, SERIES A, LIFE SCIENCES 1003 0% 1% 3
7 NATURE CELL BIOLOGY 943 1% 0% 8
8 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 492 4% 0% 30
9 MECHANISMS OF DEVELOPMENT 454 1% 0% 6
10 PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 403 1% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SPROUTY 1393124 8% 56% 62 Search SPROUTY Search SPROUTY
2 LRIG1 1290913 5% 84% 38 Search LRIG1 Search LRIG1
3 MIG 6 764363 3% 100% 19 Search MIG+6 Search MIG+6
4 ACK1 643666 3% 80% 20 Search ACK1 Search ACK1
5 SPROUTY2 473274 3% 59% 20 Search SPROUTY2 Search SPROUTY2
6 RALT 325858 1% 90% 9 Search RALT Search RALT
7 LRIG 321837 1% 100% 8 Search LRIG Search LRIG
8 LRIG3 321837 1% 100% 8 Search LRIG3 Search LRIG3
9 UROFACIAL SYNDROME 296233 1% 82% 9 Search UROFACIAL+SYNDROME Search UROFACIAL+SYNDROME
10 SPRED 268191 1% 67% 10 Search SPRED Search SPRED

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MASOUMI-MOGHADDAM, S , AMINI, A , MORRIS, DL , (2014) THE DEVELOPING STORY OF SPROUTY AND CANCER.CANCER AND METASTASIS REVIEWS. VOL. 33. ISSUE 2-3. P. 695 -720 112 65% 22
2 EDWIN, F , ANDERSON, K , YING, CY , PATEL, TB , (2009) INTERMOLECULAR INTERACTIONS OF SPROUTY PROTEINS AND THEIR IMPLICATIONS IN DEVELOPMENT AND DISEASE.MOLECULAR PHARMACOLOGY. VOL. 76. ISSUE 4. P. 679-691 82 60% 47
3 LINDQUIST, D , KVARNBRINK, S , HENRIKSSON, R , HEDMAN, H , (2014) LRIG AND CANCER PROGNOSIS.ACTA ONCOLOGICA. VOL. 53. ISSUE 9. P. 1135 -1142 50 79% 6
4 MASON, JM , MORRISON, DJ , BASSON, MA , LICHT, JD , (2006) SPROUTY PROTEINS: MULTIFACETED NEGATIVE-FEED BACK REGULATORS OF RECEPTOR TYROSINE KINASE SIGNALING.TRENDS IN CELL BIOLOGY. VOL. 16. ISSUE 1. P. 45 -54 47 70% 252
5 SIMION, C , CEDANO-PRIETO, ME , SWEENEY, C , (2014) THE LRIG FAMILY: ENIGMATIC REGULATORS OF GROWTH FACTOR RECEPTOR SIGNALING.ENDOCRINE-RELATED CANCER. VOL. 21. ISSUE 6. P. R431 -R443 50 65% 6
6 MASOUMI-MOGHADDAM, S , AMINI, A , WEI, AQ , ROBERTSON, G , MORRIS, DL , (2015) SPROUTY 2 PROTEIN, BUT NOT SPROUTY 4, IS AN INDEPENDENT PROGNOSTIC BIOMARKER FOR HUMAN EPITHELIAL OVARIAN CANCER.INTERNATIONAL JOURNAL OF CANCER. VOL. 137. ISSUE 3. P. 560 -570 39 75% 4
7 KRAL, R , DORIGUZZI, A , MAYER, CE , KRENBEK, D , SETINEK, U , SUTTERLUTY-FALL, H , (2016) DIFFERENTIAL EFFECTS OF VARIATIONS AT CODON 106 ON SPROUTY2 FUNCTIONS IN LUNG CANCER-DERIVED CELLS.JOURNAL OF CELLULAR BIOCHEMISTRY. VOL. 117. ISSUE 8. P. 1822 -1832 35 85% 0
8 RATHMANNER, N , HAIGL, B , VANAS, V , DORIGUZZI, A , GSUR, A , SUTTERLUTY-FALL, H , (2013) SPROUTY2 BUT NOT SPROUTY4 IS A POTENT INHIBITOR OF CELL PROLIFERATION AND MIGRATION OF OSTEOSARCOMA CELLS.FEBS LETTERS. VOL. 587. ISSUE 16. P. 2597-2605 35 83% 9
9 CABRITA, MA , CHRISTOFORI, G , (2008) SPROUTY PROTEINS, MASTERMINDS OF RECEPTOR TYROSINE KINASE SIGNALING.ANGIOGENESIS. VOL. 11. ISSUE 1. P. 53-62 50 53% 125
10 DORIGUZZI, A , SALHI, J , SUTTERLUTY-FALL, H , (2016) SPROUTY4 MRNA VARIANTS AND PROTEIN EXPRESSIONS IN BREAST AND LUNG-DERIVED CELLS.ONCOLOGY LETTERS. VOL. 12. ISSUE 5. P. 4161 -4166 32 84% 0

Classes with closest relation at Level 2


Rank Class id link
1 1927 FGF21//FIBROBLAST GROWTH FACTOR//FIBROBLAST GROWTH FACTOR 21
2 1648 EPIDERMAL GROWTH FACTOR//HB EGF//TRANSFORMING GROWTH FACTOR ALPHA
3 536 X LINKED AGAMMAGLOBULINEMIA//BTK//SH2 DOMAIN
4 3581 PHOSPHOENOLPYRUVATE CARBOXYKINASE//GLYCERONEOGENESIS//BROWN ADIPOSE TISSUE HEMIDENERVATION
5 1195 JNK//ERK5//MAP KINASE
6 3956 RKIP//RAF KINASE INHIBITOR PROTEIN//HIPPOCAMPAL CHOLINERGIC NEUROSTIMULATING PEPTIDE
7 349 DEVELOPMENTAL BIOLOGY//DEVELOPMENT//NEURAL CREST
8 1911 FARNESYLTRANSFERASE//RAS//RAL
9 3833 CITED2//BRANCHIO OCULO FACIAL SYNDROME//AP 2 ALPHA
10 4146 PIM KINASE//PIM 1//PIM 2

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