Class information for:
Level 1: SPROUTY//SPROUTY2//SPRED

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
23744 336 41.5 96%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
3948 2             SPROUTY//LRIG1//MIG 6 759
23744 1                   SPROUTY//SPROUTY2//SPRED 336

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SPROUTY authKW 3147123 18% 56% 62
2 SPROUTY2 authKW 1069142 6% 59% 20
3 SPRED authKW 605850 3% 67% 10
4 SPRED2 authKW 445300 2% 70% 7
5 SPROUTY4 authKW 445300 2% 70% 7
6 SPRY2 authKW 422922 3% 42% 11
7 SPRY4 authKW 408950 2% 75% 6
8 SEF authKW 312638 5% 20% 17
9 SPROUTY1 authKW 296862 2% 47% 7
10 HSEF authKW 272635 1% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 1651 36% 0% 122
2 Developmental Biology 1068 12% 0% 39
3 Biochemistry & Molecular Biology 732 40% 0% 135
4 Oncology 456 21% 0% 69
5 Genetics & Heredity 132 10% 0% 32
6 Biophysics 47 5% 0% 18
7 Medicine, Research & Experimental 36 5% 0% 17
8 Anatomy & Morphology 31 1% 0% 5
9 Cell & Tissue Engineering 26 1% 0% 3
10 Reproductive Biology 18 2% 0% 6

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 COOPERAT PROGRAM MOL GENET CELL BIOL 163579 1% 60% 3
2 CELLULAR BIOL NEUROSCI PROF DR E DE ROBERT 121170 1% 67% 2
3 MOL CELLULAR IMMUNOL 94929 5% 7% 16
4 AFFILIATED LISHUI HOSPAFFILIATED HOSP 5CENT HOS 90878 0% 100% 1
5 BIOL DEV DIFF NEUROMUSCL 90878 0% 100% 1
6 BIOMED BIOL SCI BIOTECHNOL 90878 0% 100% 1
7 CHILDRENS HOSP LOS ANGELES KECK MED 90878 0% 100% 1
8 CLEVELAND VA GRECC 90878 0% 100% 1
9 COOPERAT PROGAM 90878 0% 100% 1
10 EQUIPE MORPHOGENESIS CELLULAIRE TUMORALE 90878 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NATO ADVANCED SCIENCE INSTITUTES SERIES, SERIES A, LIFE SCIENCES 2272 1% 1% 3
2 ONCOGENE 1269 5% 0% 16
3 NATURE CELL BIOLOGY 1206 2% 0% 6
4 MECHANISMS OF DEVELOPMENT 1040 2% 0% 6
5 JOURNAL OF BIOLOGICAL CHEMISTRY 782 11% 0% 37
6 MOLECULAR CANCER RESEARCH 772 1% 0% 4
7 DEVELOPMENTAL CELL 559 1% 0% 4
8 MOLECULAR MEDICINE REPORTS 528 2% 0% 6
9 CELLULAR SIGNALLING 514 1% 0% 5
10 AMERICAN JOURNAL OF CANCER RESEARCH 457 1% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SPROUTY 3147123 18% 56% 62 Search SPROUTY Search SPROUTY
2 SPROUTY2 1069142 6% 59% 20 Search SPROUTY2 Search SPROUTY2
3 SPRED 605850 3% 67% 10 Search SPRED Search SPRED
4 SPRED2 445300 2% 70% 7 Search SPRED2 Search SPRED2
5 SPROUTY4 445300 2% 70% 7 Search SPROUTY4 Search SPROUTY4
6 SPRY2 422922 3% 42% 11 Search SPRY2 Search SPRY2
7 SPRY4 408950 2% 75% 6 Search SPRY4 Search SPRY4
8 SEF 312638 5% 20% 17 Search SEF Search SEF
9 SPROUTY1 296862 2% 47% 7 Search SPROUTY1 Search SPROUTY1
10 HSEF 272635 1% 100% 3 Search HSEF Search HSEF

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MASOUMI-MOGHADDAM, S , AMINI, A , MORRIS, DL , (2014) THE DEVELOPING STORY OF SPROUTY AND CANCER.CANCER AND METASTASIS REVIEWS. VOL. 33. ISSUE 2-3. P. 695 -720 112 65% 22
2 EDWIN, F , ANDERSON, K , YING, CY , PATEL, TB , (2009) INTERMOLECULAR INTERACTIONS OF SPROUTY PROTEINS AND THEIR IMPLICATIONS IN DEVELOPMENT AND DISEASE.MOLECULAR PHARMACOLOGY. VOL. 76. ISSUE 4. P. 679-691 82 60% 47
3 MASON, JM , MORRISON, DJ , BASSON, MA , LICHT, JD , (2006) SPROUTY PROTEINS: MULTIFACETED NEGATIVE-FEED BACK REGULATORS OF RECEPTOR TYROSINE KINASE SIGNALING.TRENDS IN CELL BIOLOGY. VOL. 16. ISSUE 1. P. 45 -54 47 70% 252
4 MASOUMI-MOGHADDAM, S , AMINI, A , WEI, AQ , ROBERTSON, G , MORRIS, DL , (2015) SPROUTY 2 PROTEIN, BUT NOT SPROUTY 4, IS AN INDEPENDENT PROGNOSTIC BIOMARKER FOR HUMAN EPITHELIAL OVARIAN CANCER.INTERNATIONAL JOURNAL OF CANCER. VOL. 137. ISSUE 3. P. 560 -570 39 75% 4
5 KRAL, R , DORIGUZZI, A , MAYER, CE , KRENBEK, D , SETINEK, U , SUTTERLUTY-FALL, H , (2016) DIFFERENTIAL EFFECTS OF VARIATIONS AT CODON 106 ON SPROUTY2 FUNCTIONS IN LUNG CANCER-DERIVED CELLS.JOURNAL OF CELLULAR BIOCHEMISTRY. VOL. 117. ISSUE 8. P. 1822 -1832 35 85% 0
6 RATHMANNER, N , HAIGL, B , VANAS, V , DORIGUZZI, A , GSUR, A , SUTTERLUTY-FALL, H , (2013) SPROUTY2 BUT NOT SPROUTY4 IS A POTENT INHIBITOR OF CELL PROLIFERATION AND MIGRATION OF OSTEOSARCOMA CELLS.FEBS LETTERS. VOL. 587. ISSUE 16. P. 2597-2605 35 83% 9
7 CABRITA, MA , CHRISTOFORI, G , (2008) SPROUTY PROTEINS, MASTERMINDS OF RECEPTOR TYROSINE KINASE SIGNALING.ANGIOGENESIS. VOL. 11. ISSUE 1. P. 53-62 50 53% 125
8 DORIGUZZI, A , SALHI, J , SUTTERLUTY-FALL, H , (2016) SPROUTY4 MRNA VARIANTS AND PROTEIN EXPRESSIONS IN BREAST AND LUNG-DERIVED CELLS.ONCOLOGY LETTERS. VOL. 12. ISSUE 5. P. 4161 -4166 32 84% 0
9 ANDERSON, K , NORDQUIST, KA , GAO, XL , HICKS, KC , ZHAI, B , GYGI, SP , PATEL, TB , (2011) REGULATION OF CELLULAR LEVELS OF SPROUTY2 PROTEIN BY PROLYL HYDROXYLASE DOMAIN AND VON HIPPEL-LINDAU PROTEINS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 286. ISSUE 49. P. 42027-42036 40 69% 22
10 EDWIN, F , ANDERSON, K , PATEL, TB , (2010) HECT DOMAIN-CONTAINING E3 UBIQUITIN LIGASE NEDD4 INTERACTS WITH AND UBIQUITINATES SPROUTY2.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 285. ISSUE 1. P. 255 -264 40 63% 16

Classes with closest relation at Level 1


Rank Class id link
1 10558 FGFR//FIBROBLAST GROWTH FACTOR RECEPTOR 4//FGFR4
2 14390 CBL//CBL B//C CBL
3 9717 LUNG DEVELOPMENT//LUNG MORPHOGENESIS//BRANCHING MORPHOGENESIS
4 29090 MIG 6//ACK1//RALT
5 21005 TRACHEAL SYSTEM//TRACHEALESS//BREATHLESS
6 23594 DYRK1A//DYRK2//MINIBRAIN
7 10562 RHOMBOID//SPITZ//RHOMBOID PROTEASE
8 11748 RAF//LEO JENKINS CANC//KSR1
9 9419 DUAL SPECIFICITY PHOSPHATASE//MKP 1//MAP KINASE PHOSPHATASE
10 8749 ISTHMIC ORGANIZER//PITX3//OTX2

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