Class information for:
Level 3: BETA LACTAMS//BETA LACTAMASE//INGN PROT

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
682 8575 29.5 58%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
682 3       BETA LACTAMS//BETA LACTAMASE//INGN PROT 8575
1556 2             BETA LACTAMS//BETA LACTAMASE//INGN PROT 7389
3653 2             BETA N ACETYL D GLUCOSAMINIDASE//RAPID EQUILIBRIUM//UNSTABLE PRODUCT 1186

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BETA LACTAMS authKW 302315 4% 24% 355
2 BETA LACTAMASE authKW 142652 3% 17% 241
3 INGN PROT address 137497 1% 33% 118
4 METALLO BETA LACTAMASE authKW 134938 2% 28% 135
5 2 AZETIDINONE authKW 125147 1% 64% 55
6 1 BETA METHYLCARBAPENEM authKW 124628 0% 85% 41
7 STAUDINGER REACTION authKW 113527 1% 38% 84
8 AZOMETHINE IMINES authKW 78419 0% 57% 39
9 AZETIDIN 2 ONES authKW 76672 0% 57% 38
10 AZETIDINONES authKW 75165 1% 35% 61

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Chemistry, Organic 45966 34% 1% 2875
2 Chemistry, Medicinal 6898 9% 0% 776
3 Chemistry, Multidisciplinary 5759 19% 0% 1633
4 Microbiology 4579 11% 0% 936
5 Biochemistry & Molecular Biology 3553 21% 0% 1769
6 Pharmacology & Pharmacy 3189 14% 0% 1164
7 Biotechnology & Applied Microbiology 453 5% 0% 396
8 Biophysics 417 4% 0% 315
9 Crystallography 383 2% 0% 212
10 Mathematical & Computational Biology 324 1% 0% 124

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INGN PROT 137497 1% 33% 118
2 CHIM B6 34055 0% 23% 42
3 STRUCT FUNCT PHYS CHEM 25307 0% 89% 8
4 GRP CRISTALLOG BIOL 23343 0% 41% 16
5 ELECT ENGN ELECT AUTOMAT COMMUN 21797 0% 88% 7
6 QUIM ORGAN 1 18933 1% 8% 69
7 GRP MODELIZAC BIOQUIM 16013 0% 75% 6
8 MOL ERS DRUG DESIGN DISCOVERY DELIVERY 13169 0% 37% 10
9 PHARMACOL MOL BIOL MICROBIOL 12450 0% 50% 7
10 NORWEGIAN STRUCT BIOL NORSTRUCT 11624 0% 30% 11

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF ANTIBIOTICS 55443 4% 5% 323
2 TETRAHEDRON LETTERS 18043 7% 1% 621
3 HETEROCYCLES 13466 3% 2% 226
4 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 12580 3% 1% 294
5 JOURNAL OF ORGANIC CHEMISTRY 7968 4% 1% 349
6 TETRAHEDRON 7882 3% 1% 294
7 BIOCHEMICAL JOURNAL 6599 3% 1% 239
8 JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 6030 2% 1% 141
9 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 5274 2% 1% 199
10 JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS 3536 2% 1% 134

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BETA LACTAMS 302315 4% 24% 355 Search BETA+LACTAMS Search BETA+LACTAMS
2 BETA LACTAMASE 142652 3% 17% 241 Search BETA+LACTAMASE Search BETA+LACTAMASE
3 METALLO BETA LACTAMASE 134938 2% 28% 135 Search METALLO+BETA+LACTAMASE Search METALLO+BETA+LACTAMASE
4 2 AZETIDINONE 125147 1% 64% 55 Search 2+AZETIDINONE Search 2+AZETIDINONE
5 1 BETA METHYLCARBAPENEM 124628 0% 85% 41 Search 1+BETA+METHYLCARBAPENEM Search 1+BETA+METHYLCARBAPENEM
6 STAUDINGER REACTION 113527 1% 38% 84 Search STAUDINGER+REACTION Search STAUDINGER+REACTION
7 AZOMETHINE IMINES 78419 0% 57% 39 Search AZOMETHINE+IMINES Search AZOMETHINE+IMINES
8 AZETIDIN 2 ONES 76672 0% 57% 38 Search AZETIDIN+2+ONES Search AZETIDIN+2+ONES
9 AZETIDINONES 75165 1% 35% 61 Search AZETIDINONES Search AZETIDINONES
10 PENICILLIN BINDING PROTEIN 69758 1% 25% 77 Search PENICILLIN+BINDING+PROTEIN Search PENICILLIN+BINDING+PROTEIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 DRAWZ, SM , BONOMO, RA , (2010) THREE DECADES OF BETA-LACTAMASE INHIBITORS.CLINICAL MICROBIOLOGY REVIEWS. VOL. 23. ISSUE 1. P. 160-+ 236 62% 374
2 FARINA, D , SPYRAKIS, F , VENTURELLI, A , CROSS, S , TONDI, D , COSTI, MP , (2014) THE INHIBITION OF EXTENDED SPECTRUM BETA-LACTAMASES: HITS AND LEADS.CURRENT MEDICINAL CHEMISTRY. VOL. 21. ISSUE 12. P. 1405 -1434 162 72% 5
3 KARSISIOTIS, AI , DAMBLON, CF , ROBERTS, GCK , (2014) A VARIETY OF ROLES FOR VERSATILE ZINC IN METALLO-BETA-LACTAMASES.METALLOMICS. VOL. 6. ISSUE 7. P. 1181 -1197 105 88% 20
4 ARANDA, MT , PEREZ-FAGINAS, P , GONZALEZ-MUNIZ, R , (2009) AN UPDATE ON THE SYNTHESIS OF BETA-LACTAMS.CURRENT ORGANIC SYNTHESIS. VOL. 6. ISSUE 3. P. 325-341 146 67% 42
5 FISHER, JF , MEROUEH, SO , MOBASHERY, S , (2005) BACTERIAL RESISTANCE TO BETA-LACTAM ANTIBIOTICS: COMPELLING OPPORTUNISM, COMPELLING OPPORTUNITY.CHEMICAL REVIEWS. VOL. 105. ISSUE 2. P. 395-424 163 45% 456
6 PALZKILL, T , (2013) METALLO-BETA-LACTAMASE STRUCTURE AND FUNCTION.ANTIMICROBIAL THERAPEUTICS REVIEWS: THE BACTERIAL CELL WALL AS AN ANTIMICROBIAL TARGET. VOL. 1277. ISSUE . P. 91-104 84 82% 62
7 XU, JX , (2012) SYNTHESIS OF BETA-LACTAMS WITH PI ELECTRON-WITHDRAWING SUBSTITUENTS.TETRAHEDRON. VOL. 68. ISSUE 52. P. 10696-10747 155 55% 19
8 PALOMO, C , AIZPURUA, JM , GANBOA, I , OIARBIDE, M , (1999) ASYMMETRIC SYNTHESIS OF BETA-LACTAMS BY STAUDINGER KETENE-IMINE CYCLOADDITION REACTION.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. VOL. . ISSUE 12. P. 3223 -3235 108 89% 248
9 BEBRONE, C , LASSAUX, P , VERCHEVAL, L , SOHIER, JS , JEHAES, A , SAUVAGE, E , GALLENI, M , (2010) CURRENT CHALLENGES IN ANTIMICROBIAL CHEMOTHERAPY FOCUS ON BETA-LACTAMASE INHIBITION.DRUGS. VOL. 70. ISSUE 6. P. 651 -679 117 67% 64
10 FAST, W , SUTTON, LD , (2013) METALLO-BETA-LACTAMASE: INHIBITORS AND REPORTER SUBSTRATES.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1834. ISSUE 8. P. 1648 -1659 85 83% 32

Classes with closest relation at Level 3


Rank Class id link
1 233 JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY//ANTIMICROBIAL AGENTS AND CHEMOTHERAPY//FLUOROQUINOLONES
2 654 POLYOXYMETHYLENE DIMETHYL ETHERS//CROSS INTERACTION CONSTANT//PSEUDOACID
3 534 PYRIMIDINOPHANES//SOLID PHASE SYNTHESIS//INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH
4 73 MICROBIOLOGY//INFECTIOUS DISEASES//STAPHYLOCOCCUS AUREUS
5 9 CHEMISTRY, ORGANIC//JOURNAL OF HETEROCYCLIC CHEMISTRY//KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII
6 1 CHEMISTRY, ORGANIC//TETRAHEDRON LETTERS//JOURNAL OF ORGANIC CHEMISTRY
7 239 LIPASE//JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC//BIOCATALYSIS
8 278 CORYNEBACTERIUM GLUTAMICUM//ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY//BIOCHEMISTRY & MOLECULAR BIOLOGY
9 673 SIDEROPHORE//COLICIN//UREASE
10 408 CHIM BIOINORGAN//POLO SCI//CARBONIC ANHYDRASE

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