Class information for:
Level 1: APE1//AP ENDONUCLEASE//APE1 REF 1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11880 947 45.7 85%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
142 3       DNA REPAIR//INTERNATIONAL JOURNAL OF RADIATION BIOLOGY//RADIATION RESEARCH 64602
1228 2             BASE EXCISION REPAIR//DNA GLYCOSYLASE//OXIDATIVE DNA DAMAGE 9086
11880 1                   APE1//AP ENDONUCLEASE//APE1 REF 1 947

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 APE1 authKW 1201480 8% 51% 73
2 AP ENDONUCLEASE authKW 720474 5% 43% 52
3 APE1 REF 1 authKW 681119 3% 81% 26
4 REF 1 authKW 665557 4% 61% 34
5 APURINIC APYRIMIDINIC ENDONUCLEASE authKW 403030 2% 83% 15
6 APE REF 1 authKW 305696 2% 59% 16
7 BASE EXCISION REPAIR authKW 262643 9% 10% 81
8 ENDONUCLEASE IV authKW 260086 1% 73% 11
9 PEDIATSECT HEMATOL ONCOL address 205326 1% 58% 11
10 APEX NUCLEASE authKW 193457 1% 100% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 3637 52% 0% 488
2 Toxicology 891 10% 0% 93
3 Genetics & Heredity 644 12% 0% 114
4 Oncology 641 15% 0% 144
5 Cell Biology 552 14% 0% 133
6 Biophysics 218 7% 0% 62
7 Biotechnology & Applied Microbiology 66 5% 0% 48
8 Endocrinology & Metabolism 36 4% 0% 35
9 Biology 30 2% 0% 22
10 Biochemical Research Methods 17 2% 0% 23

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEDIATSECT HEMATOL ONCOL 205326 1% 58% 11
2 GRP REPARAT ADN 118439 1% 28% 13
3 BIOCHEM BIOPHYS BIOL SCI 72545 0% 75% 3
4 GRP REPARAT ADNUMR 8200 72545 0% 75% 3
5 MOL GERONTOL 71748 4% 6% 35
6 BIOTECHNOL BIOMED LEIPZIG 64486 0% 100% 2
7 HERMAN B WELLS PEDIAT 61559 4% 5% 40
8 EMERGING LIFE SCI TECHNOL 58035 0% 60% 3
9 SECT HEMATOL ONCOLHERMAN B WELLS PEDIAT 58035 0% 60% 3
10 SEALY MOL SCI 47468 2% 6% 23

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DNA REPAIR 19379 4% 2% 35
2 MUTATION RESEARCH-DNA REPAIR 14868 2% 3% 15
3 NUCLEIC ACIDS RESEARCH 5546 9% 0% 83
4 ANTIOXIDANTS & REDOX SIGNALING 2999 2% 1% 17
5 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 982 1% 0% 11
6 JOURNAL OF BIOLOGICAL CHEMISTRY 757 7% 0% 63
7 MOLECULAR AND CELLULAR BIOLOGY 730 2% 0% 23
8 BIOCHEMISTRY 688 4% 0% 35
9 ENVIRONMENTAL CARCINOGENESIS REVIEWS-PART C OF JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH 618 0% 2% 1
10 JOURNAL OF MOLECULAR BIOLOGY 468 2% 0% 19

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 APE1 1201480 8% 51% 73 Search APE1 Search APE1
2 AP ENDONUCLEASE 720474 5% 43% 52 Search AP+ENDONUCLEASE Search AP+ENDONUCLEASE
3 APE1 REF 1 681119 3% 81% 26 Search APE1+REF+1 Search APE1+REF+1
4 REF 1 665557 4% 61% 34 Search REF+1 Search REF+1
5 APURINIC APYRIMIDINIC ENDONUCLEASE 403030 2% 83% 15 Search APURINIC+APYRIMIDINIC+ENDONUCLEASE Search APURINIC+APYRIMIDINIC+ENDONUCLEASE
6 APE REF 1 305696 2% 59% 16 Search APE+REF+1 Search APE+REF+1
7 BASE EXCISION REPAIR 262643 9% 10% 81 Search BASE+EXCISION+REPAIR Search BASE+EXCISION+REPAIR
8 ENDONUCLEASE IV 260086 1% 73% 11 Search ENDONUCLEASE+IV Search ENDONUCLEASE+IV
9 APEX NUCLEASE 193457 1% 100% 6 Search APEX+NUCLEASE Search APEX+NUCLEASE
10 APURINIC APYRIMIDINIC ENDONUCLEASE1 REDOX FACTOR 1 193457 1% 100% 6 Search APURINIC+APYRIMIDINIC+ENDONUCLEASE1+REDOX+FACTOR+1 Search APURINIC+APYRIMIDINIC+ENDONUCLEASE1+REDOX+FACTOR+1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LI, MX , WILSON, DM , (2014) HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE 1.ANTIOXIDANTS & REDOX SIGNALING. VOL. 20. ISSUE 4. P. 678 -707 163 72% 36
2 KAUR, G , CHOLIA, RP , MANTHA, AK , KUMAR, R , (2014) DNA REPAIR AND REDOX ACTIVITIES AND INHIBITORS OF APURINIC/APYRIMIDINIC ENDONUCLEASE 1/REDOX EFFECTOR FACTOR 1 (APE1/REF-1): A COMPARATIVE ANALYSIS AND THEIR SCOPE AND LIMITATIONS TOWARD ANTICANCER DRUG DEVELOPMENT.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 57. ISSUE 24. P. 10241 -10256 108 79% 8
3 BHAKAT, KK , MANTHA, AK , MITRA, S , (2009) TRANSCRIPTIONAL REGULATORY FUNCTIONS OF MAMMALIAN AP-ENDONUCLEASE (APE1/REF-1), AN ESSENTIAL MULTIFUNCTIONAL PROTEIN.ANTIOXIDANTS & REDOX SIGNALING. VOL. 11. ISSUE 3. P. 621 -637 98 63% 90
4 TELL, G , QUADRIFOGLIO, F , TIRIBELLI, C , KELLEY, MR , (2009) THE MANY FUNCTIONS OF APE1/REF-1: NOT ONLY A DNA REPAIR ENZYME.ANTIOXIDANTS & REDOX SIGNALING. VOL. 11. ISSUE 3. P. 601 -619 91 61% 148
5 TELL, G , DAMANTE, G , CALDWELL, D , KELLEY, MR , (2005) THE INTRACELLULAR LOCALIZATION OF APE1/REF-1: MORE THAN A PASSIVE PHENOMENON?.ANTIOXIDANTS & REDOX SIGNALING. VOL. 7. ISSUE 3-4. P. 367 -384 90 63% 229
6 EVANS, AR , LIMP-FOSTER, M , KELLEY, MR , (2000) GOING APE OVER REF-1.MUTATION RESEARCH-DNA REPAIR. VOL. 461. ISSUE 2. P. 83-108 93 62% 392
7 ABBOTTS, R , MADHUSUDAN, S , (2010) HUMAN AP ENDONUCLEASE 1 (APE1): FROM MECHANISTIC INSIGHTS TO DRUGGABLE TARGET IN CANCER.CANCER TREATMENT REVIEWS. VOL. 36. ISSUE 5. P. 425 -435 87 62% 68
8 BAPAT, A , FISHEL, ML , KELLEY, MR , (2009) GOING APE AS AN APPROACH TO CANCER THERAPEUTICS.ANTIOXIDANTS & REDOX SIGNALING. VOL. 11. ISSUE 3. P. 651 -667 90 66% 36
9 TELL, G , FANTINI, D , QUADRIFOGLIO, F , (2010) UNDERSTANDING DIFFERENT FUNCTIONS OF MAMMALIAN AP ENDONUCLEASE (APE1) AS A PROMISING TOOL FOR CANCER TREATMENT.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 67. ISSUE 21. P. 3589 -3608 85 64% 39
10 THAKUR, S , SARKAR, B , CHOLIA, RP , GAUTAM, N , DHIMAN, M , MANTHA, AK , (2014) APE1/REF-1 AS AN EMERGING THERAPEUTIC TARGET FOR VARIOUS HUMAN DISEASES: PHYTOCHEMICAL MODULATION OF ITS FUNCTIONS.EXPERIMENTAL AND MOLECULAR MEDICINE. VOL. 46. ISSUE . P. - 102 45% 21

Classes with closest relation at Level 1


Rank Class id link
1 1886 DNA GLYCOSYLASE//BASE EXCISION REPAIR//8 OXOGUANINE
2 23453 ABASIC SITE//REGULATORY BIOORGAN CHEM//CHIM BIOORGANLEDSS
3 10667 URACIL DNA GLYCOSYLASE//DUTPASE//MBD4
4 21108 FEN1//BRAUN S//CREAT INITIAT CELL CYCLE CONTROL
5 5439 DNA POLYMERASE BETA//DNA POLYMERASE//DNA POLYMERASE LAMBDA
6 2272 XRCC1//XRCC3//XPD
7 25015 ADV AGING BRAIN//AMALAKI RASAYANA//DNA GAP REPAIR
8 19766 TRNA SPLICING//POLYNUCLEOTIDE KINASE//SPLICING ENDONUCLEASE
9 11475 LES ACIDES NUCL//SPIROIMINODIHYDANTOIN//CHEM 027
10 1097 MGMT//O 6 METHYLGUANINE DNA METHYLTRANSFERASE//O 6 ALKYLGUANINE DNA ALKYLTRANSFERASE

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