Class information for:
Level 1: CHEK2//PALB2//CHK2

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15199 726 40.3 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
512 3       BRCA1//BRCA2//FANCONI ANEMIA 21435
900 2             BRCA1//BRCA2//FANCONI ANEMIA 11301
15199 1                   CHEK2//PALB2//CHK2 726

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHEK2 authKW 2594459 11% 75% 82
2 PALB2 authKW 1861609 8% 76% 58
3 CHK2 authKW 911788 10% 31% 70
4 CHEK2 1100DELC authKW 336467 1% 100% 8
5 RAD51C authKW 319846 2% 45% 17
6 CHEK2 GENE authKW 309699 1% 82% 9
7 CHECKPOINT KINASE 2 authKW 309026 2% 57% 13
8 BRIP1 authKW 221252 2% 48% 11
9 CHK2 GENE authKW 210292 1% 100% 5
10 1100DELC authKW 168233 1% 100% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 7696 53% 0% 385
2 Genetics & Heredity 2987 27% 0% 198
3 Cell Biology 575 16% 0% 116
4 Biochemistry & Molecular Biology 435 24% 0% 172
5 Biophysics 29 3% 0% 25
6 Chemistry, Medicinal 10 2% 0% 14
7 Obstetrics & Gynecology 5 2% 0% 12
8 Medicine, Research & Experimental 5 2% 0% 16
9 Developmental Biology 3 1% 0% 6
10 Hematology 2 1% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INT HEREDITARY CANC 138659 4% 11% 29
2 MARY BAAB RANDOLPH CANC 84117 0% 100% 2
3 N SCOTLAND CLIN GENET SERV 84117 0% 100% 2
4 PROGRAM CANC GENET 76605 3% 9% 21
5 ABT GYN TUMORGENET 56076 0% 67% 2
6 CANGENETEST CONSORTIUM GENET SERV 56076 0% 67% 2
7 KATHLEEN CUNNINGHAM FDN CONSORTIUM FAMILIAL B 56076 0% 67% 2
8 PENINSULA REG GENET SERV 56076 0% 67% 2
9 CANC GENET TUMOR BIOL 48053 1% 14% 8
10 BIOCHEM EXPT ONCOL 46200 1% 11% 10

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FAMILIAL CANCER 27671 3% 3% 24
2 HEREDITARY CANCER IN CLINICAL PRACTICE 23090 1% 5% 10
3 BREAST CANCER RESEARCH AND TREATMENT 18858 8% 1% 57
4 BREAST CANCER RESEARCH 6250 2% 1% 18
5 JOURNAL OF GENETIC COUNSELING 2272 1% 1% 6
6 BALKAN JOURNAL OF MEDICAL GENETICS 1747 0% 1% 3
7 GENETICS IN MEDICINE 1656 1% 0% 8
8 CANCER GENETICS 1621 1% 1% 4
9 MEDIZINISCHE GENETIK 1619 0% 1% 3
10 JOURNAL OF MEDICAL GENETICS 1403 2% 0% 14

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CHEK2 2594459 11% 75% 82 Search CHEK2 Search CHEK2
2 PALB2 1861609 8% 76% 58 Search PALB2 Search PALB2
3 CHK2 911788 10% 31% 70 Search CHK2 Search CHK2
4 CHEK2 1100DELC 336467 1% 100% 8 Search CHEK2+1100DELC Search CHEK2+1100DELC
5 RAD51C 319846 2% 45% 17 Search RAD51C Search RAD51C
6 CHEK2 GENE 309699 1% 82% 9 Search CHEK2+GENE Search CHEK2+GENE
7 CHECKPOINT KINASE 2 309026 2% 57% 13 Search CHECKPOINT+KINASE+2 Search CHECKPOINT+KINASE+2
8 BRIP1 221252 2% 48% 11 Search BRIP1 Search BRIP1
9 CHK2 GENE 210292 1% 100% 5 Search CHK2+GENE Search CHK2+GENE
10 1100DELC 168233 1% 100% 4 Search 1100DELC Search 1100DELC

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 ANTONI, L , SODHA, N , COLLINS, I , GARRETT, MD , (2007) CHK2 KINASE: CANCER SUSCEPTIBILITY AND CANCER THERAPY - TWO SIDES OF THE SAME COIN?.NATURE REVIEWS CANCER. VOL. 7. ISSUE 12. P. 925 -936 84 65% 153
2 NEVANLINNA, H , BARTEK, J , (2006) THE CHEK2 GENE AND INHERITED BREAST CANCER SUSCEPTIBILITY.ONCOGENE. VOL. 25. ISSUE 43. P. 5912 -5919 58 82% 92
3 DESRICHARD, A , BIDET, Y , UHRHAMMER, N , BIGNON, YJ , (2011) CHEK2 CONTRIBUTION TO HEREDITARY BREAST CANCER IN NON-BRCA FAMILIES.BREAST CANCER RESEARCH. VOL. 13. ISSUE 6. P. - 46 75% 18
4 NAROD, SA , (2010) TESTING FOR CHEK2 IN THE CANCER GENETICS CLINIC: READY FOR PRIME TIME?.CLINICAL GENETICS. VOL. 78. ISSUE 1. P. 1 -7 43 80% 29
5 ANGELOVA, SG , KRASTEVA, ME , GOSPODINOVA, ZI , GEORGIEVA, EI , (2012) CHEK2 GENE ALTERATIONS INDEPENDENTLY INCREASE THE RISK OF DEATH FROM BREAST CANCER IN BULGARIAN PATIENTS.NEOPLASMA. VOL. 59. ISSUE 6. P. 622-630 44 77% 3
6 RASHID, MU , MUHAMMAD, N , FAISAL, S , AMIN, A , HAMANN, U , (2013) CONSTITUTIONAL CHEK2 MUTATIONS ARE INFREQUENT IN EARLY-ONSET AND FAMILIAL BREAST/OVARIAN CANCER PATIENTS FROM PAKISTAN.BMC CANCER. VOL. 13. ISSUE . P. - 38 84% 5
7 MOHAMAD, S , LSA, NM , MUHAMMAD, R , EMRAN, NA , KITAN, NM , KANG, P , KANG, IN , TAID, NAM , TEO, SH , AKMAL, SN , (2015) LOW PREVALENCE OF CHEK2 GENE MUTATIONS IN MULTIETHNIC COHORTS OF BREAST CANCER PATIENTS IN MALAYSIA.PLOS ONE. VOL. 10. ISSUE 1. P. - 33 94% 0
8 CECENER, G , ESKILER, GG , EGELI, U , TUNCA, B , ALEMDAR, A , GOKGOZ, S , TASDELEN, I , (2016) ASSOCIATION OF PALB2 SEQUENCE VARIANTS WITH THE RISK OF EARLY-ONSET BREAST CANCER IN PATIENTS FROM TURKEY.MOLECULAR BIOLOGY REPORTS. VOL. 43. ISSUE 11. P. 1273 -1284 34 85% 0
9 CATUCCI, I , MILGROM, R , KUSHNIR, A , LAITMAN, Y , PALUCH-SHIMON, S , VOLORIO, S , FICARAZZI, F , BERNARD, L , RADICE, P , FRIEDMAN, E , ET AL (2012) GERMLINE MUTATIONS IN BRIP1 AND PALB2 IN JEWISH HIGH CANCER RISK FAMILIES.FAMILIAL CANCER. VOL. 11. ISSUE 3. P. 483 -491 36 82% 15
10 WEISCHER, M , BOJESEN, SE , ELLERVIK, C , TYBJAERG-HANSEN, A , NORDESTGAARD, BG , (2008) CHEK2* 1100DELC GENOTYPING FOR CLINICAL ASSESSMENT OF BREAST CANCER RISK: META-ANALYSES OF 26,000 PATIENT CASES AND 27,000 CONTROLS.JOURNAL OF CLINICAL ONCOLOGY. VOL. 26. ISSUE 4. P. 542-548 31 91% 98

Classes with closest relation at Level 1


Rank Class id link
1 17719 CANC GENET EPIDEMIOL//SERV CIRUGIA GEN ESPECIALIDADES//UNIT MOL BASES GENET RISK GENET TESTING
2 471 BRCA2//BRCA1//HEREDITARY BREAST CANCER
3 2448 CHK1//CHECKPOINT//RAD9
4 19114 LI FRAUMENI SYNDROME//LI FRAUMENI//GERMLINE TP53 MUTATION
5 5107 BRCA1//BARD1//BRCA2
6 3535 NIJMEGEN BREAKAGE SYNDROME//NBS1//MRE11
7 3284 FANCONI ANEMIA//FANCONI ANAEMIA//FANCD2
8 5917 ATAXIA TELANGIECTASIA//ATM//ATM GENE
9 23203 HEREDITARY DIFFUSE GASTRIC CANCER//PROPHYLACTIC GASTRECTOMY//HDGC
10 23185 WIP1//PPM1D//CELL CYCLE CONTROL TUMORIGENESIS GRP

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