Class information for:
Level 2: BRCA1//BRCA2//FANCONI ANEMIA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
900 11301 40.8 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
512 3       BRCA1//BRCA2//FANCONI ANEMIA 21435
900 2             BRCA1//BRCA2//FANCONI ANEMIA 11301
471 1                   BRCA2//BRCA1//HEREDITARY BREAST CANCER 3398
3284 1                   FANCONI ANEMIA//FANCONI ANAEMIA//FANCD2 2020
5107 1                   BRCA1//BARD1//BRCA2 1672
8040 1                   HEREDITARY PROSTATE CANCER//RNASEL//8Q24 1300
10345 1                   PARP INHIBITORS//OLAPARIB//SYNTHETIC LETHALITY 1071
15199 1                   CHEK2//PALB2//CHK2 726
17719 1                   CANC GENET EPIDEMIOL//SERV CIRUGIA GEN ESPECIALIDADES//UNIT MOL BASES GENET RISK GENET TESTING 586
18965 1                   CONTRALATERAL PROPHYLACTIC MASTECTOMY//BILATERAL BREAST CANCER//CONTRALATERAL BREAST CANCER 528

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 BRCA1 authKW 2801530 14% 64% 1633
2 BRCA2 authKW 2081644 9% 72% 1064
3 FANCONI ANEMIA authKW 1084594 5% 77% 525
4 PARP INHIBITORS authKW 284628 2% 57% 186
5 HEREDITARY BREAST CANCER authKW 278601 1% 65% 160
6 BRCA authKW 259297 2% 45% 213
7 CANC GENET EPIDEMIOL address 239483 1% 53% 168
8 CHEK2 authKW 218851 1% 86% 94
9 FANCONI ANAEMIA authKW 190048 1% 80% 88
10 OLAPARIB authKW 178119 1% 82% 80

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 96769 48% 1% 5414
2 Genetics & Heredity 33601 23% 1% 2647
3 Cell Biology 4194 12% 0% 1320
4 Biochemistry & Molecular Biology 2031 15% 0% 1748
5 Hematology 1968 5% 0% 545
6 Obstetrics & Gynecology 1371 4% 0% 467
7 Urology & Nephrology 519 3% 0% 311
8 Medicine, Research & Experimental 324 3% 0% 366
9 Pathology 243 2% 0% 231
10 Public, Environmental & Occupational Health 223 3% 0% 373

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANC GENET EPIDEMIOL 239483 1% 53% 168
2 FAMILY CANC CLIN 169823 1% 53% 119
3 INT HEREDITARY CANC 160065 1% 48% 123
4 UNIT MOL BASES GENET RISK GENET TESTING 140452 1% 68% 76
5 PROGRAM CANC GENET 109235 1% 41% 99
6 FAMILIAL BREAST OVARIAN CANC 90129 0% 70% 48
7 CANC GENET TUMOR BIOL 81028 0% 73% 41
8 ONTARIO CANC GENET NETWORK 80437 0% 65% 46
9 UNIT MED GENET 79329 1% 27% 110
10 CLIN CANC GENET 78277 1% 37% 79

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FAMILIAL CANCER 94330 2% 20% 175
2 BREAST CANCER RESEARCH AND TREATMENT 73730 4% 6% 446
3 HEREDITARY CANCER IN CLINICAL PRACTICE 51562 1% 32% 59
4 BREAST CANCER RESEARCH 24848 1% 7% 142
5 CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 17200 2% 3% 202
6 HUMAN MUTATION 11635 1% 3% 132
7 NATURE GENETICS 8864 1% 3% 129
8 JOURNAL OF MEDICAL GENETICS 8530 1% 2% 137
9 PROSTATE 7004 1% 2% 110
10 HUMAN MOLECULAR GENETICS 6907 1% 2% 161

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 BRCA1 2801530 14% 64% 1633 Search BRCA1 Search BRCA1
2 BRCA2 2081644 9% 72% 1064 Search BRCA2 Search BRCA2
3 FANCONI ANEMIA 1084594 5% 77% 525 Search FANCONI+ANEMIA Search FANCONI+ANEMIA
4 PARP INHIBITORS 284628 2% 57% 186 Search PARP+INHIBITORS Search PARP+INHIBITORS
5 HEREDITARY BREAST CANCER 278601 1% 65% 160 Search HEREDITARY+BREAST+CANCER Search HEREDITARY+BREAST+CANCER
6 BRCA 259297 2% 45% 213 Search BRCA Search BRCA
7 CHEK2 218851 1% 86% 94 Search CHEK2 Search CHEK2
8 FANCONI ANAEMIA 190048 1% 80% 88 Search FANCONI+ANAEMIA Search FANCONI+ANAEMIA
9 OLAPARIB 178119 1% 82% 80 Search OLAPARIB Search OLAPARIB
10 PROPHYLACTIC MASTECTOMY 168126 1% 73% 85 Search PROPHYLACTIC+MASTECTOMY Search PROPHYLACTIC+MASTECTOMY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KARAMI, F , MEHDIPOUR, P , (2013) A COMPREHENSIVE FOCUS ON GLOBAL SPECTRUM OF BRCA1 AND BRCA2 MUTATIONS IN BREAST CANCER.BIOMED RESEARCH INTERNATIONAL. VOL. . ISSUE . P. - 166 94% 14
2 MOLDOVAN, GL , D'ANDREA, AD , (2009) HOW THE FANCONI ANEMIA PATHWAY GUARDS THE GENOME.ANNUAL REVIEW OF GENETICS. VOL. 43. ISSUE . P. 223-249 128 83% 272
3 THOMPSON, LH , HINZ, JM , (2009) CELLULAR AND MOLECULAR CONSEQUENCES OF DEFECTIVE FANCONI ANEMIA PROTEINS IN REPLICATION-COUPLED DNA REPAIR: MECHANISTIC INSIGHTS.MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. VOL. 668. ISSUE 1-2. P. 54 -72 186 72% 94
4 PAUL, A , PAUL, S , (2014) THE BREAST CANCER SUSCEPTIBILITY GENES (BRCA) IN BREAST AND OVARIAN CANCERS.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 19. ISSUE . P. 605-618 153 83% 15
5 PRAKASH, R , ZHANG, Y , FENG, WR , JASIN, M , (2015) HOMOLOGOUS RECOMBINATION AND HUMAN HEALTH: THE ROLES OF BRCA1, BRCA2, AND ASSOCIATED PROTEINS.COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. VOL. 7. ISSUE 4. P. - 143 53% 53
6 NAROD, SA , FOULKES, WD , (2004) BRCA1 AND BRCA2: 1994 AND BEYOND.NATURE REVIEWS CANCER. VOL. 4. ISSUE 9. P. 665-676 130 80% 455
7 CECCALDI, R , SARANGI, P , D'ANDREA, AD , (2016) THE FANCONI ANAEMIA PATHWAY: NEWYPLAYERS AND NEW FUNCTIONS.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 17. ISSUE 6. P. 337 -349 99 73% 11
8 YUAN, FH , SONG, LM , QIAN, LY , HU, JJ , ZHANG, YB , (2010) ASSEMBLING AN ORCHESTRA: FANCONI ANEMIA PATHWAY OF DNA REPAIR.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 15. ISSUE . P. 1131-1149 172 79% 3
9 LYNCH, HT , KOSOKO-LASAKI, O , LESLIE, SW , RENDELL, M , SHAW, T , SNYDER, C , D'AMICO, AV , BUXBAUM, S , ISAACS, WB , LOEB, S , ET AL (2016) SCREENING FOR FAMILIAL AND HEREDITARY PROSTATE CANCER.INTERNATIONAL JOURNAL OF CANCER. VOL. 138. ISSUE 11. P. 2579 -2591 115 85% 3
10 GUIDUGLI, L , CARREIRA, A , CAPUTO, SM , EHLEN, A , GALLI, A , MONTEIRO, ANA , NEUHAUSEN, SL , HANSEN, TVO , COUCH, FJ , VREESWIJK, MPG , (2014) FUNCTIONAL ASSAYS FOR ANALYSIS OF VARIANTS OF UNCERTAIN SIGNIFICANCE IN BRCA2.HUMAN MUTATION. VOL. 35. ISSUE 2. P. 151 -164 118 92% 12

Classes with closest relation at Level 2


Rank Class id link
1 1039 GENETIC TESTING//BIOBANK//JOURNAL OF GENETIC COUNSELING
2 2606 FHIT//WWOX//FRAGILE SITES
3 271 INTERNATIONAL JOURNAL OF RADIATION BIOLOGY//RADIATION RESEARCH//ATAXIA TELANGIECTASIA
4 1071 LYNCH SYNDROME//MICROSATELLITE INSTABILITY//HNPCC
5 700 TELOMERASE//TELOMERE//TELOMERE LENGTH
6 827 MAMMOGRAPHIC DENSITY//BREAST DENSITY//METFORMIN
7 1422 XRCC1//GEMCITABINE//ERCC1
8 160 WERNER SYNDROME//DNA POLYMERASE//DNA REPAIR
9 936 P53//MDM2//P73
10 652 HER2//TRASTUZUMAB//HER 2 NEU

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