Class information for:
Level 1: CHK1//CHECKPOINT//RAD9

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2448 2241 51.5 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
142 3       DNA REPAIR//INTERNATIONAL JOURNAL OF RADIATION BIOLOGY//RADIATION RESEARCH 64602
271 2             INTERNATIONAL JOURNAL OF RADIATION BIOLOGY//RADIATION RESEARCH//ATAXIA TELANGIECTASIA 19288
2448 1                   CHK1//CHECKPOINT//RAD9 2241

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHK1 authKW 1874342 11% 55% 248
2 CHECKPOINT authKW 760394 10% 24% 235
3 RAD9 authKW 442550 2% 69% 47
4 ATR authKW 357442 7% 18% 150
5 CLASPIN authKW 331383 1% 81% 30
6 TOPBP1 authKW 272742 1% 65% 31
7 CHECKPOINT KINASE 1 authKW 267174 1% 63% 31
8 DNA DAMAGE CHECKPOINT authKW 236241 2% 38% 46
9 CELL CYCLE CHECKPOINT authKW 227899 4% 21% 81
10 MEC1 authKW 224984 1% 52% 32

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Cell Biology 19716 48% 0% 1071
2 Biochemistry & Molecular Biology 5368 42% 0% 938
3 Genetics & Heredity 4372 19% 0% 432
4 Oncology 3687 22% 0% 501
5 Developmental Biology 604 4% 0% 82
6 Toxicology 350 5% 0% 101
7 Chemistry, Medicinal 145 3% 0% 71
8 Biophysics 54 3% 0% 66
9 Biology 28 2% 0% 39
10 Mycology 11 0% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENOM ABIL GRP 78800 1% 32% 18
2 GENOME DAMAGE STABIL 30693 2% 6% 36
3 47S 9A 27248 0% 100% 2
4 4MD 10 27248 0% 100% 2
5 4N6 9 27248 0% 100% 2
6 MBL INA 27248 0% 100% 2
7 GENOME DYNAM PROJECT 27232 0% 20% 10
8 ENVIRONM HLTH SUSCEPTIBIL 26491 1% 16% 12
9 CELL CYCLE CANC 26410 0% 24% 8
10 CELL MUTAT UNIT 22116 1% 13% 13

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 37088 5% 2% 116
2 DNA REPAIR 30887 3% 3% 68
3 MOLECULAR AND CELLULAR BIOLOGY 7274 5% 0% 110
4 GENES & DEVELOPMENT 6951 3% 1% 62
5 MOLECULAR CELL 6937 2% 1% 53
6 MOLECULAR CANCER THERAPEUTICS 6418 2% 1% 44
7 CELL CYCLE 5960 1% 3% 17
8 MOLECULAR BIOLOGY OF THE CELL 4692 2% 1% 54
9 CELL DIVISION 4217 0% 4% 8
10 ONCOGENE 3389 3% 0% 68

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CHK1 1874342 11% 55% 248 Search CHK1 Search CHK1
2 CHECKPOINT 760394 10% 24% 235 Search CHECKPOINT Search CHECKPOINT
3 RAD9 442550 2% 69% 47 Search RAD9 Search RAD9
4 ATR 357442 7% 18% 150 Search ATR Search ATR
5 CLASPIN 331383 1% 81% 30 Search CLASPIN Search CLASPIN
6 TOPBP1 272742 1% 65% 31 Search TOPBP1 Search TOPBP1
7 CHECKPOINT KINASE 1 267174 1% 63% 31 Search CHECKPOINT+KINASE+1 Search CHECKPOINT+KINASE+1
8 DNA DAMAGE CHECKPOINT 236241 2% 38% 46 Search DNA+DAMAGE+CHECKPOINT Search DNA+DAMAGE+CHECKPOINT
9 CELL CYCLE CHECKPOINT 227899 4% 21% 81 Search CELL+CYCLE+CHECKPOINT Search CELL+CYCLE+CHECKPOINT
10 MEC1 224984 1% 52% 32 Search MEC1 Search MEC1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ZHANG, YW , HUNTER, T , (2014) ROLES OF CHK1 IN CELL BIOLOGY AND CANCER THERAPY.INTERNATIONAL JOURNAL OF CANCER. VOL. 134. ISSUE 5. P. 1013 -1023 126 66% 42
2 HUSTEDT, N , GASSER, SM , SHIMADA, K , (2013) REPLICATION CHECKPOINT: TUNING AND COORDINATION OF REPLICATION FORKS IN S PHASE.GENES. VOL. 4. ISSUE 3. P. 388-434 185 56% 12
3 CIMPRICH, KA , CORTEZ, D , (2008) ATR: AN ESSENTIAL REGULATOR OF GENOME INTEGRITY.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 9. ISSUE 8. P. 616 -627 97 54% 762
4 BESTEIRO, MAG , GOTTIFREDI, V , (2015) THE FORK AND THE KINASE: A DNA REPLICATION TALE FROM A CHK1 PERSPECTIVE.MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH. VOL. 763. ISSUE . P. 168 -180 99 66% 13
5 MCNEELY, S , BECKMANN, R , LIN, AKB , (2014) CHEK AGAIN: REVISITING THE DEVELOPMENT OF CHK1 INHIBITORS FOR CANCER THERAPY.PHARMACOLOGY & THERAPEUTICS. VOL. 142. ISSUE 1. P. 1 -10 72 76% 39
6 FINN, K , LOWNDES, NF , GRENON, M , (2012) EUKARYOTIC DNA DAMAGE CHECKPOINT ACTIVATION IN RESPONSE TO DOUBLE-STRAND BREAKS.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 69. ISSUE 9. P. 1447 -1473 158 41% 31
7 THO, LM , XU, NH , GILLESPIE, DA , SMITH, J , (2010) THE ATM-CHK2 AND ATR-CHK1 PATHWAYS IN DNA DAMAGE SIGNALING AND CANCER.ADVANCES IN CANCER RESEARCH, VOL 108. VOL. 108. ISSUE . P. 73 -112 91 47% 339
8 SORENSEN, CS , SYLJUASEN, RG , (2012) SAFEGUARDING GENOME INTEGRITY: THE CHECKPOINT KINASES ATR, CHK1 AND WEE1 RESTRAIN CDK ACTIVITY DURING NORMAL DNA REPLICATION.NUCLEIC ACIDS RESEARCH. VOL. 40. ISSUE 2. P. 477 -486 80 66% 84
9 PATIL, M , PABLA, N , DONG, Z , (2013) CHECKPOINT KINASE 1 IN DNA DAMAGE RESPONSE AND CELL CYCLE REGULATION.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 70. ISSUE 21. P. 4009 -4021 75 80% 27
10 SMITS, VAJ , WARMERDAM, DO , MARTIN, Y , FREIRE, R , (2010) MECHANISMS OF ATR-MEDIATED CHECKPOINT SIGNALLING.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 15. ISSUE . P. 840-853 91 74% 30

Classes with closest relation at Level 1


Rank Class id link
1 15199 CHEK2//PALB2//CHK2
2 3535 NIJMEGEN BREAKAGE SYNDROME//NBS1//MRE11
3 25613 UCN 01//7 HYDROXYSTAUROSPORINE//CGP41251
4 577 DNA REPLICATION//GEMININ//CDC6
5 13708 REPLICATION PROTEIN A//SINGLE STRANDED DNA BINDING PROTEIN//SSB
6 15937 CDC25B//CDC25 PHOSPHATASE//CDC25A
7 16864 G2 REPAIR//G2 DELAY//G2 M BLOCK ABROGATION
8 13797 GAMMA H2AX//GAMMA H2AX FOCI//H2AX
9 19522 REPLICATION FORK BARRIER//FORK ARREST//REPLICATION TERMINATOR PROTEIN
10 4671 RAD51//RAD52//HOMOLOGOUS RECOMBINATION

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