Class information for:
Level 1: CDC25B//CDC25 PHOSPHATASE//CDC25A

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15937 683 39.1 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
304 3       P53//RETINOBLASTOMA//MDM2 40663
483 2             CYCLIN DEPENDENT KINASE//CELL CYCLE//CDK5 15640
15937 1                   CDC25B//CDC25 PHOSPHATASE//CDC25A 683

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CDC25B authKW 1497386 8% 59% 57
2 CDC25 PHOSPHATASE authKW 914430 4% 68% 30
3 CDC25A authKW 606574 6% 32% 42
4 CDC25 INHIBITORS authKW 584162 2% 93% 14
5 VITAMIN K2 authKW 390134 4% 36% 24
6 CDC25 authKW 310615 5% 19% 37
7 P423 authKW 238429 1% 67% 8
8 LBCMCP address 196673 3% 20% 22
9 CDC25B PHOSPHATASE authKW 182545 1% 58% 7
10 LBCMCP UMR5088 address 156465 1% 50% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 2245 31% 0% 209
2 Cell Biology 1170 22% 0% 153
3 Chemistry, Medicinal 1016 12% 0% 82
4 Biochemistry & Molecular Biology 708 29% 0% 201
5 Chemistry, Organic 190 9% 0% 62
6 Genetics & Heredity 132 7% 0% 49
7 Pharmacology & Pharmacy 124 10% 0% 71
8 Gastroenterology & Hepatology 61 4% 0% 25
9 Medicine, Research & Experimental 33 4% 0% 26
10 Biophysics 29 4% 0% 24

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LBCMCP 196673 3% 20% 22
2 LBCMCP UMR5088 156465 1% 50% 7
3 BIOL CHEM FUNDAMENTAL MED 102183 1% 57% 4
4 UMR5088 91266 1% 29% 7
5 IFR109 EXPLORAT FONCT GENOMES 89413 0% 100% 2
6 DRUGS SCREENING 80469 0% 60% 3
7 STARZL TRANSPLANTAT 65858 2% 11% 14
8 LIVER CANC SURG 59607 0% 67% 2
9 UA4124 59607 0% 67% 2
10 IPSEN 46597 1% 15% 7

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY 5062 2% 1% 11
2 ONCOGENE 2045 4% 0% 29
3 INTERNATIONAL JOURNAL OF ONCOLOGY 1495 3% 0% 18
4 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 1287 2% 0% 12
5 VITAMINS AND HORMONES-ADVANCES IN RESEARCH AND APPLICATIONS 1079 0% 1% 3
6 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 987 4% 0% 24
7 SELECTIVE CANCER THERAPEUTICS 731 0% 2% 1
8 MOLECULAR CANCER THERAPEUTICS 526 1% 0% 7
9 JOURNAL OF CELLULAR PHYSIOLOGY 520 2% 0% 11
10 CANCER RESEARCH 473 3% 0% 21

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CDC25B 1497386 8% 59% 57 Search CDC25B Search CDC25B
2 CDC25 PHOSPHATASE 914430 4% 68% 30 Search CDC25+PHOSPHATASE Search CDC25+PHOSPHATASE
3 CDC25A 606574 6% 32% 42 Search CDC25A Search CDC25A
4 CDC25 INHIBITORS 584162 2% 93% 14 Search CDC25+INHIBITORS Search CDC25+INHIBITORS
5 VITAMIN K2 390134 4% 36% 24 Search VITAMIN+K2 Search VITAMIN+K2
6 CDC25 310615 5% 19% 37 Search CDC25 Search CDC25
7 P423 238429 1% 67% 8 Search P423 Search P423
8 CDC25B PHOSPHATASE 182545 1% 58% 7 Search CDC25B+PHOSPHATASE Search CDC25B+PHOSPHATASE
9 CDC25B INHIBITOR 143059 1% 80% 4 Search CDC25B+INHIBITOR Search CDC25B+INHIBITOR
10 MENADIONE 134364 5% 8% 36 Search MENADIONE Search MENADIONE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 BOUTROS, R , LOBJOIS, V , DUCOMMUN, B , (2007) CDC25 PHOSPHATASES IN CANCER CELLS: KEY PLAYERS? GOOD TARGETS?.NATURE REVIEWS CANCER. VOL. 7. ISSUE 7. P. 495-507 84 57% 313
2 LAVECCHIA, A , DI GIOVANNI, C , NOVELLINO, E , (2012) CDC25 PHOSPHATASE INHIBITORS: AN UPDATE.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 12. ISSUE 1. P. 62 -73 53 79% 34
3 GARUTI, L , ROBERTI, M , PIZZIRANI, D , (2008) SYNTHETIC SMALL MOLECULE CDC25 PHOSPHATASES INHIBITORS.CURRENT MEDICINAL CHEMISTRY. VOL. 15. ISSUE 6. P. 573-580 47 89% 7
4 LAVECCHIA, A , DI GIOVANNI, C , NOVELLINO, E , (2009) CDC25A AND B DUAL-SPECIFICITY PHOSPHATASE INHIBITORS: POTENTIAL AGENTS FOR CANCER THERAPY.CURRENT MEDICINAL CHEMISTRY. VOL. 16. ISSUE 15. P. 1831-1849 62 58% 19
5 SUR, S , AGRAWAL, DK , (2016) PHOSPHATASES AND KINASES REGULATING CDC25 ACTIVITY IN THE CELL CYCLE: CLINICAL IMPLICATIONS OF CDC25 OVEREXPRESSION AND POTENTIAL TREATMENT STRATEGIES.MOLECULAR AND CELLULAR BIOCHEMISTRY. VOL. 416. ISSUE 1-2. P. 33 -46 50 57% 1
6 KRISTJANSDOTTIR, K , RUDOLPH, J , (2004) CDC25 PHOSPHATASES AND CANCER.CHEMISTRY & BIOLOGY. VOL. 11. ISSUE 8. P. 1043-1051 42 74% 193
7 LAVECCHIA, A , DI GIOVANNI, C , NOVELLINO, E , (2010) INHIBITORS OF CDC25 PHOSPHATASES AS ANTICANCER AGENTS: A PATENT REVIEW.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 20. ISSUE 3. P. 405-425 48 59% 33
8 LAVECCHIA, A , COLUCCIA, A , DI GIOVANNI, C , NOVELLINO, E , (2008) CDC25B PHOSPHATASE INHIBITORS IN CANCER THERAPY: LATEST DEVELOPMENTS, TRENDS AND MEDICINAL CHEMISTRY PERSPECTIVE.ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. VOL. 8. ISSUE 8. P. 843-856 56 57% 8
9 BOUTROS, R , DOZIER, C , DUCOMMUN, B , (2006) THE WHEN AND WHERES OF CDC25 PHOSPHATASES.CURRENT OPINION IN CELL BIOLOGY. VOL. 18. ISSUE 2. P. 185-191 40 59% 268
10 LYON, MA , DUCRUET, AP , WIPF, P , LAZO, JS , (2002) DUAL-SPECIFICITY PHOSPHATASES AS TARGETS FOR ANTINEOPLASTIC AGENTS.NATURE REVIEWS DRUG DISCOVERY. VOL. 1. ISSUE 12. P. 961 -976 61 51% 100

Classes with closest relation at Level 1


Rank Class id link
1 2551 MPF//CDC2//GREATWALL
2 2448 CHK1//CHECKPOINT//RAD9
3 9419 DUAL SPECIFICITY PHOSPHATASE//MKP 1//MAP KINASE PHOSPHATASE
4 15554 NUTRIENT MIXTURE//AUTOSCHIZIS//MATRIGEL INVASION
5 1580 PROTEIN TYROSINE PHOSPHATASE//PTP1B//PROTEIN TYROSINE PHOSPHATASE 1B
6 5347 VITAMIN K//PHYLLOQUINONE//VITAMIN K 2
7 17875 LAVENDAMYCIN//ETNOFARMACOL IDE//QUINOLINE 5 8 DIONES
8 11497 POLO LIKE KINASE 1//PLK1//POLO LIKE KINASE
9 26359 VITAMIN K 3//MENADIONE SODIUM BISULFITE//MODERN METALS
10 23606 CAK//SPY1//CDK ACTIVATING KINASE

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