Class information for:
Level 1: TAXOL//PACLITAXEL//BCL 2 PHOSPHORYLATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15859 688 41.5 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
216 3       NON SMALL CELL LUNG CANCER//LUNG CANCER//THORAC SURG 51214
1102 2             PACLITAXEL//TAXANES//EPOTHILONES 9807
15859 1                   TAXOL//PACLITAXEL//BCL 2 PHOSPHORYLATION 688

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TAXOL authKW 280027 13% 7% 90
2 PACLITAXEL authKW 136401 20% 2% 137
3 BCL 2 PHOSPHORYLATION authKW 118340 1% 33% 8
4 TAXANE SB T 1216 authKW 88763 0% 100% 2
5 MITOTIC ARREST authKW 59769 2% 8% 16
6 HEMATOL ONCOLWINSHIP CANC address 59174 0% 67% 2
7 MICROTUBULE ACTIVE DRUGS authKW 59174 0% 67% 2
8 PHARMACOLRAMMELKAMP EDUC address 59174 0% 67% 2
9 RECH ONCOL BIOL ONCOPHARMACOL PHARM address 59174 0% 67% 2
10 10 DEACETYLBACCATINIII authKW 44381 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 5499 46% 0% 319
2 Cell Biology 1028 21% 0% 145
3 Pharmacology & Pharmacy 431 17% 0% 115
4 Biochemistry & Molecular Biology 302 21% 0% 145
5 Immunology 78 7% 0% 48
6 Hematology 65 4% 0% 26
7 Biophysics 36 4% 0% 26
8 Toxicology 29 3% 0% 19
9 Medicine, Research & Experimental 22 3% 0% 23
10 Genetics & Heredity 20 4% 0% 26

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEMATOL ONCOLWINSHIP CANC 59174 0% 67% 2
2 PHARMACOLRAMMELKAMP EDUC 59174 0% 67% 2
3 RECH ONCOL BIOL ONCOPHARMACOL PHARM 59174 0% 67% 2
4 AFFILIATED FIRST PEOPLE HOSP 44381 0% 100% 1
5 AGR BIOL SCINAKA KU 44381 0% 100% 1
6 ANTI NEOPLAST PHARMACOL 44381 0% 100% 1
7 BCMB 44381 0% 100% 1
8 BIOENERGET PROT ENGN 44381 0% 100% 1
9 BIOL WSPEC BIOINFORMAT 44381 0% 100% 1
10 BIOMOL DRUG DISCOVERY 44381 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF INFLAMMATION 2243 0% 3% 2
2 ANTI-CANCER DRUGS 1628 2% 0% 11
3 INTERNATIONAL JOURNAL OF ONCOLOGY 1484 3% 0% 18
4 CANCER RESEARCH 1428 5% 0% 36
5 PEZCOLLER FOUNDATION SYMPOSIA 1394 1% 0% 8
6 CANCER CHEMOTHERAPY AND PHARMACOLOGY 1338 2% 0% 15
7 CLINICAL CANCER RESEARCH 1289 3% 0% 21
8 ANTICANCER RESEARCH 1197 3% 0% 23
9 ONCOGENE 953 3% 0% 20
10 CANCER CELL INTERNATIONAL 919 1% 1% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TAXOL 280027 13% 7% 90 Search TAXOL Search TAXOL
2 PACLITAXEL 136401 20% 2% 137 Search PACLITAXEL Search PACLITAXEL
3 BCL 2 PHOSPHORYLATION 118340 1% 33% 8 Search BCL+2+PHOSPHORYLATION Search BCL+2+PHOSPHORYLATION
4 TAXANE SB T 1216 88763 0% 100% 2 Search TAXANE+SB+T+1216 Search TAXANE+SB+T+1216
5 MITOTIC ARREST 59769 2% 8% 16 Search MITOTIC+ARREST Search MITOTIC+ARREST
6 MICROTUBULE ACTIVE DRUGS 59174 0% 67% 2 Search MICROTUBULE+ACTIVE+DRUGS Search MICROTUBULE+ACTIVE+DRUGS
7 10 DEACETYLBACCATINIII 44381 0% 100% 1 Search 10+DEACETYLBACCATINIII Search 10+DEACETYLBACCATINIII
8 2 3 METHOXYPHENYL 6 7 METHYLENEDIOXOQUINOLIN 4 ONE 44381 0% 100% 1 Search 2+3+METHOXYPHENYL+6+7+METHYLENEDIOXOQUINOLIN+4+ONE Search 2+3+METHOXYPHENYL+6+7+METHYLENEDIOXOQUINOLIN+4+ONE
9 2 ARYL 6 SUBSTITUTED QUINAZOLINONES 44381 0% 100% 1 Search 2+ARYL+6+SUBSTITUTED+QUINAZOLINONES Search 2+ARYL+6+SUBSTITUTED+QUINAZOLINONES
10 5 FLUOROURACIL AND CISPLATIN THERAPY 44381 0% 100% 1 Search 5+FLUOROURACIL+AND+CISPLATIN+THERAPY Search 5+FLUOROURACIL+AND+CISPLATIN+THERAPY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 WANG, TH , WANG, HS , SOONG, YK , (2000) PACLITAXEL-INDUCED CELL DEATH - WHERE THE CELL CYCLE AND APOPTOSIS COME TOGETHER.CANCER. VOL. 88. ISSUE 11. P. 2619-2628 56 46% 348
2 BLAGOSKLONNY, MV , FOJO, T , (1999) MOLECULAR EFFECTS OF PACLITAXEL: MYTHS AND REALITY (A CRITICAL REVIEW).INTERNATIONAL JOURNAL OF CANCER. VOL. 83. ISSUE 2. P. 151 -156 47 51% 269
3 ESTEVE, MA , CARRE, M , BRAGUER, D , (2007) MICROTUBULES IN APOPTOSIS INDUCTION: ARE THEY NECESSARY?.CURRENT CANCER DRUG TARGETS. VOL. 7. ISSUE 8. P. 713-729 76 28% 35
4 ABAL, M , ANDREU, JM , BARASOAIN, I , (2003) TAXANES: MICROTUBULE AND CENTROSOME TARGETS, AND CELL CYCLE DEPENDENT MECHANISMS OF ACTION.CURRENT CANCER DRUG TARGETS. VOL. 3. ISSUE 3. P. 193-203 50 35% 166
5 SEIDMAN, R , GITELMAN, I , SAGI, O , HORWITZ, SB , WOLFSON, M , (2001) THE ROLE OF ERK 1/2 AND P38 MAP-KINASE PATHWAYS IN TAXOL-INDUCED APOPTOSIS IN HUMAN OVARIAN CARCINOMA CELLS.EXPERIMENTAL CELL RESEARCH. VOL. 268. ISSUE 1. P. 84 -92 29 63% 78
6 ZHAO, JS , KIM, JE , REED, E , LI, QQ , (2005) MOLECULAR MECHANISM OF ANTITUMOR ACTIVITY OF TAXANES IN LUNG CANCER (REVIEW).INTERNATIONAL JOURNAL OF ONCOLOGY. VOL. 27. ISSUE 1. P. 247-256 45 37% 42
7 FITZPATRICK, FA , WHEELER, R , (2003) THE IMMUNOPHANNACOLOGY OF PACLITAXEL (TAXOL (R)) DOCETAXEL (TAXOTERE (R)), AND RELATED AGENTS.INTERNATIONAL IMMUNOPHARMACOLOGY. VOL. 3. ISSUE 13-14. P. 1699-1714 38 42% 60
8 JAVEED, A , ASHRAF, M , RIAZ, A , GHAFOOR, A , AFZAL, S , MUKHTAR, MM , (2009) PACLITAXEL AND IMMUNE SYSTEM.EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. VOL. 38. ISSUE 4. P. 283-290 35 37% 45
9 BLAGOSKLONNY, MV , (2001) UNWINDING THE LOOP OF BCL-2 PHOSPHORYLATION.LEUKEMIA. VOL. 15. ISSUE 6. P. 869 -874 34 41% 101
10 FAN, WM , (1999) POSSIBLE MECHANISMS OF PACLITAXEL-INDUCED APOPTOSIS.BIOCHEMICAL PHARMACOLOGY. VOL. 57. ISSUE 11. P. 1215 -1221 24 59% 103

Classes with closest relation at Level 1


Rank Class id link
1 7277 PACLITAXEL//CREMOPHOR EL//DOCETAXEL
2 10628 EPOTHILONES//IXABEPILONE//PATUPILONE
3 33929 TUBULYSIN//PYRROLO 1 5 BENZOXAZEPINES//PBOX
4 31094 CHICK EMBRYO SKIN FIBROBLAST//80 K PHOSPHORYLATION//ANEMIZED RATS
5 33210 PARAPTOSIS//BAP31//AIP1 ALIX
6 19375 OBLIMERSEN//G3139//ANTISENSE BCL 2
7 37421 BCL2L12//BCL2L12A//BRAIN TUMOR GENET MED
8 5476 COMBRETASTATIN//COMBRETASTATIN A 4//VASCULAR DISRUPTING AGENTS
9 2951 TAXACEAE//TAXOIDS//TAXUS CUSPIDATA
10 640 MCL 1//BCL 2 FAMILY//BH3 MIMETIC

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