Class information for:
Level 1: TRIOSEPHOSPHATE ISOMERASE//TRIOSEPHOSPHATE ISOMERASE DEFICIENCY//BIOQUIM BIOL ESTRUCT

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
17636 589 40.7 65%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
278 3       CORYNEBACTERIUM GLUTAMICUM//ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY//BIOCHEMISTRY & MOLECULAR BIOLOGY 43163
2622 2             TRIOSEPHOSPHATE ISOMERASE//HISTIDINE BIOSYNTHESIS//KETOSTEROID ISOMERASE 3550
17636 1                   TRIOSEPHOSPHATE ISOMERASE//TRIOSEPHOSPHATE ISOMERASE DEFICIENCY//BIOQUIM BIOL ESTRUCT 589

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TRIOSEPHOSPHATE ISOMERASE authKW 3434821 22% 51% 131
2 TRIOSEPHOSPHATE ISOMERASE DEFICIENCY authKW 368649 1% 89% 8
3 BIOQUIM BIOL ESTRUCT address 247809 2% 34% 14
4 SPECIES SPECIFIC INHIBITION authKW 155525 1% 100% 3
5 BIOQUIM GENET address 152332 2% 24% 12
6 TIM authKW 150785 3% 18% 16
7 TRIOSEPHOSPHATE ISOMERASE TIM authKW 116642 1% 75% 3
8 GLYCOLYTIC ENZYMOPATHY authKW 103683 0% 100% 2
9 MONOMERIC TIM authKW 103683 0% 100% 2
10 MONOTIM authKW 103683 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 3243 61% 0% 357
2 Biophysics 672 13% 0% 77
3 Genetics & Heredity 428 12% 0% 73
4 Biochemical Research Methods 134 6% 0% 35
5 Biology 93 4% 0% 25
6 Parasitiology 67 2% 0% 14
7 Hematology 42 3% 0% 20
8 MEDICINE, MISCELLANEOUS 31 0% 0% 1
9 Chemistry, Medicinal 29 3% 0% 17
10 Crystallography 29 3% 0% 15

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOQUIM BIOL ESTRUCT 247809 2% 34% 14
2 BIOQUIM GENET 152332 2% 24% 12
3 POST BIOMED MOL 103683 0% 100% 2
4 UNIV ESTRUCT PROT 103683 0% 100% 2
5 FISICOQUIM INGN PROT 88863 1% 29% 6
6 AREA BIOFIS QUIM 82942 1% 40% 4
7 INVEST ALIMENTOS NUTR 66650 1% 43% 3
8 AREA RADIOFARM 58318 1% 38% 3
9 FISIOL CELULAR 56837 7% 3% 43
10 MOL BIOL GENET UNIT 52786 3% 6% 18

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEMISTRY 6508 14% 0% 82
2 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 2606 3% 0% 18
3 PROTEINS-STRUCTURE FUNCTION AND GENETICS 1860 1% 1% 4
4 PROTEIN ENGINEERING 1843 2% 0% 9
5 JOURNAL OF MOLECULAR BIOLOGY 1586 5% 0% 27
6 ISOZYMES-CURRENT TOPICS IN BIOLOGICAL AND MEDICAL RESEARCH 1456 0% 1% 2
7 PROTEIN ENGINEERING DESIGN & SELECTION 1239 1% 0% 5
8 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 940 2% 0% 9
9 PROTEIN SCIENCE 810 2% 0% 10
10 UKRAINSKII BIOKHIMICHESKII ZHURNAL 711 1% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TRIOSEPHOSPHATE ISOMERASE 3434821 22% 51% 131 Search TRIOSEPHOSPHATE+ISOMERASE Search TRIOSEPHOSPHATE+ISOMERASE
2 TRIOSEPHOSPHATE ISOMERASE DEFICIENCY 368649 1% 89% 8 Search TRIOSEPHOSPHATE+ISOMERASE+DEFICIENCY Search TRIOSEPHOSPHATE+ISOMERASE+DEFICIENCY
3 SPECIES SPECIFIC INHIBITION 155525 1% 100% 3 Search SPECIES+SPECIFIC+INHIBITION Search SPECIES+SPECIFIC+INHIBITION
4 TIM 150785 3% 18% 16 Search TIM Search TIM
5 TRIOSEPHOSPHATE ISOMERASE TIM 116642 1% 75% 3 Search TRIOSEPHOSPHATE+ISOMERASE+TIM Search TRIOSEPHOSPHATE+ISOMERASE+TIM
6 GLYCOLYTIC ENZYMOPATHY 103683 0% 100% 2 Search GLYCOLYTIC+ENZYMOPATHY Search GLYCOLYTIC+ENZYMOPATHY
7 MONOMERIC TIM 103683 0% 100% 2 Search MONOMERIC+TIM Search MONOMERIC+TIM
8 MONOTIM 103683 0% 100% 2 Search MONOTIM Search MONOTIM
9 PGK TIM FUSION PROTEIN 103683 0% 100% 2 Search PGK+TIM+FUSION+PROTEIN Search PGK+TIM+FUSION+PROTEIN
10 PLASMODIUM FALCIPARUM TRIOSEPHOSPHATE ISOMERASE 103683 0% 100% 2 Search PLASMODIUM+FALCIPARUM+TRIOSEPHOSPHATE+ISOMERASE Search PLASMODIUM+FALCIPARUM+TRIOSEPHOSPHATE+ISOMERASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 WIERENGA, RK , KAPETANIOU, EG , VENKATESAN, R , (2010) TRIOSEPHOSPHATE ISOMERASE: A HIGHLY EVOLVED BIOCATALYST.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 67. ISSUE 23. P. 3961 -3982 72 69% 74
2 ROLAND, BP , AMRICH, CG , KAMMERER, CJ , STUCHUL, KA , LARSEN, SB , RODE, S , ASLAM, AA , HEROUX, A , WETZEL, R , VANDEMARK, AP , ET AL (2015) TRIOSEPHOSPHATE ISOMERASE I170V ALTERS CATALYTIC SITE, ENHANCES STABILITY AND INDUCES PATHOLOGY IN A DROSOPHILA MODEL OF TPI DEFICIENCY.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. VOL. 1852. ISSUE 1. P. 61 -69 51 78% 3
3 MALABANAN, MM , KOUDELKA, AP , AMYES, TL , RICHARD, JP , (2012) MECHANISM FOR ACTIVATION OF TRIOSEPHOSPHATE ISOMERASE BY PHOSPHITE DIANION: THE ROLE OF A HYDROPHOBIC CLAMP.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. VOL. 134. ISSUE 24. P. 10286-10298 43 93% 3
4 RICHARD, JP , AMYES, TL , MALABANAN, MM , ZHAI, X , KIM, KJ , REINHARDT, CJ , WIERENGA, RK , DRAKE, EJ , GULICK, AM , (2016) STRUCTURE-FUNCTION STUDIES OF HYDROPHOBIC RESIDUES THAT CLAMP A BASIC GLUTAMATE SIDE CHAIN DURING CATALYSIS BY TRIOSEPHOSPHATE ISOMERASE.BIOCHEMISTRY. VOL. 55. ISSUE 21. P. 3036 -3047 39 78% 2
5 RICHARD, JP , ZHAI, X , MALABANAN, MM , (2014) REFLECTIONS ON THE CATALYTIC POWER OF A TIM-BARREL.BIOORGANIC CHEMISTRY. VOL. 57. ISSUE . P. 206 -212 50 69% 4
6 ZHAI, X , GO, MK , O'DONOGHUE, AC , AMYES, TL , PEGAN, SD , WANG, Y , LORIA, JP , MESECAR, AD , RICHARD, JP , (2014) ENZYME ARCHITECTURE: THE EFFECT OF REPLACEMENT AND DELETION MUTATIONS OF LOOP 6 ON CATALYSIS BY TRIOSEPHOSPHATE ISOMERASE.BIOCHEMISTRY. VOL. 53. ISSUE 21. P. 3486-3501 50 69% 3
7 SCHNEIDER, AS , (2000) TRIOSEPHOSPHATE ISOMERASE DEFICIENCY: HISTORICAL PERSPECTIVES AND MOLECULAR ASPECTS.BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY. VOL. 13. ISSUE 1. P. 119 -140 50 89% 67
8 ZARATE-PEREZ, F , CHANEZ-CARDENAS, ME , VAZQUEZ-CONTRERAS, E , (2008) THE FOLDING PATHWAY OF TRIOSEPHOSPHATE ISOMERASE.MOLECULAR BIOLOGY OF PROTEIN FOLDING, PT B. VOL. 84. ISSUE . P. 251 -267 42 84% 4
9 ZHAI, X , AMYES, TL , RICHARD, JP , (2015) ROLE OF LOOP-CLAMPING SIDE CHAINS IN CATALYSIS BY TRIOSEPHOSPHATE ISOMERASE.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. VOL. 137. ISSUE 48. P. 15185 -15197 50 59% 1
10 MALABANAN, MM , AMYES, TL , RICHARD, JP , (2010) A ROLE FOR FLEXIBLE LOOPS IN ENZYME CATALYSIS.CURRENT OPINION IN STRUCTURAL BIOLOGY. VOL. 20. ISSUE 6. P. 702 -710 39 72% 44

Classes with closest relation at Level 1


Rank Class id link
1 24160 ODCASE//OROTIDINE 5 MONOPHOSPHATE DECARBOXYLASE//MOL DESIGN PREFORMULAT
2 36450 CORRELATION SIGNS//DETERIORATION ZONES//FEMALE GENERATIVE SYSTEM
3 22175 HISTIDINE BIOSYNTHESIS//BETA ALPHA8 BARREL//INDOLE 3 GLYCEROL PHOSPHATE SYNTHASE
4 19833 AUTOCRINE MOTILITY FACTOR//AUTOCRINE MOTILITY FACTOR RECEPTOR//PHOSPHOGLUCOSE ISOMERASE
5 20583 PHOSPHOGLYCERATE KINASE//PHOSPHOGLYCERATE KINASE DEFICIENCY//PGK1
6 14403 KETOSTEROID ISOMERASE//LOW BARRIER HYDROGEN BOND//JULIUS SPOKOJNY BIOORGAN CHEM
7 24744 MANDELATE RACEMASE//MANDELATE RACEMASE EC 5122//ENOLASE SUPERFAMILY
8 17105 HYDROGEN TUNNELLING//PROMOTING VIBRATION//HYDROGEN TUNNELING
9 12643 PSYCHROPHILE//COLD ADAPTATION//THERMOPHILIC PROTEIN
10 14878 FRUCTOSE 1 6 BISPHOSPHATE ALDOLASE//HEREDITARY FRUCTOSE INTOLERANCE//ALDOLASE

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