Class information for:
Level 1: CYTOCHROME P450//S BIOCHEM//ONE DAY TREATMENT

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1927 2419 38.2 60%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
230 3       P GLYCOPROTEIN//FMO3//TRIMETHYLAMINURIA 49374
415 2             CYTOCHROME P450//CYP2D6//PREGNANE X RECEPTOR 16559
1927 1                   CYTOCHROME P450//S BIOCHEM//ONE DAY TREATMENT 2419

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYTOCHROME P450 authKW 85804 10% 3% 239
2 S BIOCHEM address 85542 1% 34% 20
3 ONE DAY TREATMENT authKW 64908 0% 86% 6
4 CYP2C11 authKW 52567 1% 28% 15
5 CYP2C12 authKW 45073 0% 71% 5
6 BIOCHEMICAL PHARMACOLOGY journal 41267 10% 1% 246
7 AROCHLOR 1254 authKW 40387 0% 80% 4
8 CYP3A9 authKW 37864 0% 100% 3
9 DRUG METABOLISM MURINE authKW 37864 0% 100% 3
10 RAT LIVER CYTOCHROME P450 authKW 37864 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pharmacology & Pharmacy 10424 39% 0% 943
2 Biochemistry & Molecular Biology 6108 43% 0% 1036
3 Toxicology 5028 14% 0% 343
4 Biophysics 2854 13% 0% 321
5 Endocrinology & Metabolism 148 4% 0% 104
6 Biochemical Research Methods 39 2% 0% 57
7 Medicine, Research & Experimental 19 2% 0% 56
8 Biology 18 2% 0% 37
9 Genetics & Heredity 15 3% 0% 63
10 Oncology 13 4% 0% 86

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 S BIOCHEM 85542 1% 34% 20
2 MOL PATHOL ECOL BIOCHEM 13457 0% 27% 4
3 1500 SPRING GARDEN ST 12621 0% 100% 1
4 CLIN PHARMACOL DU CANE RD 12621 0% 100% 1
5 COE PROGRAM CENTURY 21 CENTURY 12621 0% 100% 1
6 CYCLOOXYGENASE TECHNOL 2 12621 0% 100% 1
7 DIPARTIMENTP SANITA PUBBL PATOL COMPARATA IGIEN 12621 0% 100% 1
8 H MED PHARMACEUT SCI 12621 0% 100% 1
9 HATANO CELLULAR TOXICOL 12621 0% 100% 1
10 HLTH SCI MED MED TOXICOL SECT 12621 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEMICAL PHARMACOLOGY 41267 10% 1% 246
2 XENOBIOTICA 22907 3% 2% 84
3 DRUG METABOLISM AND DISPOSITION 22119 5% 2% 115
4 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 18873 7% 1% 160
5 JOURNAL OF BIOCHEMICAL TOXICOLOGY 9599 1% 5% 14
6 MOLECULAR PHARMACOLOGY 8804 3% 1% 83
7 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 7466 1% 4% 16
8 JOURNAL OF BIOCHEMISTRY 3474 2% 1% 55
9 DRUG METABOLISM REVIEWS 3219 1% 2% 16
10 BIOCHEMISTRY-MOSCOW 2589 2% 1% 39

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CYTOCHROME P450 85804 10% 3% 239 Search CYTOCHROME+P450 Search CYTOCHROME+P450
2 ONE DAY TREATMENT 64908 0% 86% 6 Search ONE+DAY+TREATMENT Search ONE+DAY+TREATMENT
3 CYP2C11 52567 1% 28% 15 Search CYP2C11 Search CYP2C11
4 CYP2C12 45073 0% 71% 5 Search CYP2C12 Search CYP2C12
5 AROCHLOR 1254 40387 0% 80% 4 Search AROCHLOR+1254 Search AROCHLOR+1254
6 CYP3A9 37864 0% 100% 3 Search CYP3A9 Search CYP3A9
7 DRUG METABOLISM MURINE 37864 0% 100% 3 Search DRUG+METABOLISM+MURINE Search DRUG+METABOLISM+MURINE
8 RAT LIVER CYTOCHROME P450 37864 0% 100% 3 Search RAT+LIVER+CYTOCHROME+P450 Search RAT+LIVER+CYTOCHROME+P450
9 TESTOSTERONE 6 BETA HYDROXYLASE 33654 0% 67% 4 Search TESTOSTERONE+6+BETA+HYDROXYLASE Search TESTOSTERONE+6+BETA+HYDROXYLASE
10 LIVER CYTOCHROME P450 28845 0% 57% 4 Search LIVER+CYTOCHROME+P450 Search LIVER+CYTOCHROME+P450

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 NELSON, DR , KAMATAKI, T , WAXMAN, DJ , GUENGERICH, FP , ESTABROOK, RW , FEYEREISEN, R , GONZALEZ, FJ , COON, MJ , GUNSALUS, IC , GOTOH, O , ET AL (1993) THE P450 SUPERFAMILY - UPDATE ON NEW SEQUENCES, GENE-MAPPING, ACCESSION NUMBERS, EARLY TRIVIAL NAMES OF ENZYMES, AND NOMENCLATURE.DNA AND CELL BIOLOGY. VOL. 12. ISSUE 1. P. 1-51 229 42% 1415
2 RYAN, DE , LEVIN, W , (1990) PURIFICATION AND CHARACTERIZATION OF HEPATIC-MICROSOMAL CYTOCHROME-P-450.PHARMACOLOGY & THERAPEUTICS. VOL. 45. ISSUE 2. P. 153 -239 239 62% 419
3 GONZALEZ, FJ , (1988) THE MOLECULAR-BIOLOGY OF CYTOCHROME P450S.PHARMACOLOGICAL REVIEWS. VOL. 40. ISSUE 4. P. 243-288 184 45% 306
4 GONZALEZ, FJ , (1990) MOLECULAR-GENETICS OF THE P-450 SUPERFAMILY.PHARMACOLOGY & THERAPEUTICS. VOL. 45. ISSUE 1. P. 1-38 130 43% 482
5 WAXMAN, DJ , AZAROFF, L , (1992) PHENOBARBITAL INDUCTION OF CYTOCHROME-P-450 GENE-EXPRESSION.BIOCHEMICAL JOURNAL. VOL. 281. ISSUE . P. 577-592 97 50% 493
6 NEBERT, DW , GONZALEZ, FJ , (1987) P450 GENES - STRUCTURE, EVOLUTION, AND REGULATION.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 56. ISSUE . P. 945-993 94 41% 1330
7 IOANNIDES, C , PARKE, DV , (1990) THE CYTOCHROME-P450-I GENE FAMILY OF MICROSOMAL HEMOPROTEINS AND THEIR ROLE IN THE METABOLIC-ACTIVATION OF CHEMICALS.DRUG METABOLISM REVIEWS. VOL. 22. ISSUE 1. P. 1-85 153 38% 177
8 SOUCEK, P , GUT, I , (1992) CYTOCHROMES P-450 IN RATS - STRUCTURES, FUNCTIONS, PROPERTIES AND RELEVANT HUMAN FORMS.XENOBIOTICA. VOL. 22. ISSUE 1. P. 83-103 88 57% 212
9 NEBERT, DW , NELSON, DR , ADESNIK, M , COON, MJ , ESTABROOK, RW , GONZALEZ, FJ , GUENGERICH, FP , GUNSALUS, IC , JOHNSON, EF , KEMPER, B , ET AL (1989) THE P450 SUPERFAMILY - UPDATED LISTING OF ALL GENES AND RECOMMENDED NOMENCLATURE FOR THE CHROMOSOMAL LOCI.DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY. VOL. 8. ISSUE 1. P. 1-13 72 55% 559
10 WHITLOCK, JP , (1986) THE REGULATION OF CYTOCHROME-P-450 GENE-EXPRESSION.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. VOL. 26. ISSUE . P. 333-369 93 57% 328

Classes with closest relation at Level 1


Rank Class id link
1 10357 CHLORZOXAZONE//CYP2E1//6 HYDROXYCHLORZOXAZONE
2 25968 HUMAN S9//1 1 DIBROMOBENZENE//1 METHYL 2 ARYLETHYL HYDROXYLAMINE
3 10330 CYTOCHROME P450 REDUCTASE//CYTOCHROME P4502B4//NADPH CYTOCHROME P450 REDUCTASE
4 22160 5 METHOXYTRYPTAMINE O DEMETHYLATION//BRAIN CYPS//BRAIN DRUG METABOLISM
5 15462 IN VITRO MITOGENIC STIMULATION//UMR 0938//URIDINE UPTAKE ASSAY
6 28644 O AMINOAZOTOLUENE//GLUCOCORTICOID INDUCTION//2 METHOXY 4 NITROANILINE
7 37263 PHENOBARBITAL HYDROCORTISONE//COLORECTAL TUMOR TISSUE//SENSITIVITY TO HORMONES
8 6572 SITE OF METABOLISM//CYTOCHROME P450//ATYPICAL KINETICS
9 27533 PHARMACOKINET BIOANAL//HUMANIZED LIVER//PL DEV BIOL
10 4852 6 BETA HYDROXYCORTISOL//COCKTAIL//CYP3A

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