Class information for:
Level 1: SIGNALING SYST//INTRACELLULAR DYNAMIC//NF KAPPA B SIGNAL TRANSDUCTION NETWORK

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
22276 388 45.0 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
90 3       MATHEMATICAL & COMPUTATIONAL BIOLOGY//BIOINFORMATICS//BMC BIOINFORMATICS 77178
548 2             BMC SYSTEMS BIOLOGY//MATHEMATICAL & COMPUTATIONAL BIOLOGY//BOOLEAN NETWORKS 14655
22276 1                   SIGNALING SYST//INTRACELLULAR DYNAMIC//NF KAPPA B SIGNAL TRANSDUCTION NETWORK 388

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SIGNALING SYST address 233689 4% 21% 14
2 INTRACELLULAR DYNAMIC authKW 157397 1% 100% 2
3 NF KAPPA B SIGNAL TRANSDUCTION NETWORK authKW 157397 1% 100% 2
4 P53 MDM2 NEGATIVE FEEDBACK LOOP authKW 157397 1% 100% 2
5 P53 MDM2 SYSTEM authKW 157397 1% 100% 2
6 P53 PULSE authKW 157397 1% 100% 2
7 PARABOLIC HYPERBOLIC COUPLED MODEL authKW 157397 1% 100% 2
8 REPRESSILATORS authKW 157397 1% 100% 2
9 QUANTITAT COMPUTAT BIOSCI address 122960 1% 31% 5
10 CELL IMAGING address 120519 3% 14% 11

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Mathematical & Computational Biology 7008 25% 0% 96
2 Cell Biology 1449 32% 0% 124
3 Biology 910 14% 0% 55
4 Biochemistry & Molecular Biology 691 37% 0% 143
5 Biochemical Research Methods 191 8% 0% 32
6 Biophysics 144 8% 0% 31
7 Genetics & Heredity 45 6% 0% 23
8 Physics, Mathematical 42 4% 0% 14
9 Mathematics, Applied 26 5% 0% 18
10 Biotechnology & Applied Microbiology 25 5% 0% 19

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SIGNALING SYST 233689 4% 21% 14
2 QUANTITAT COMPUTAT BIOSCI 122960 1% 31% 5
3 CELL IMAGING 120519 3% 14% 11
4 BIOPROC DESIGN 104930 1% 67% 2
5 MATH ONCOL 83939 1% 27% 4
6 BIOL BIOMED BIOSCI 78699 0% 100% 1
7 CELL INTERACT GRP 78699 0% 100% 1
8 COMPUTAT SYST BIOL TRENTO 78699 0% 100% 1
9 CRBM MACROMOL BIOCHEM 78699 0% 100% 1
10 DATA ANAL MODELING DYNAM PROC LIFE SCI 78699 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL SYSTEMS 12337 1% 4% 4
2 IET SYSTEMS BIOLOGY 11601 2% 2% 7
3 BMC SYSTEMS BIOLOGY 7050 3% 1% 12
4 MOLECULAR SYSTEMS BIOLOGY 6646 2% 1% 8
5 IEE PROCEEDINGS SYSTEMS BIOLOGY 3789 1% 2% 2
6 BIOSYSTEMS 2895 3% 0% 10
7 JOURNAL OF THEORETICAL BIOLOGY 2893 5% 0% 20
8 SCIENCE SIGNALING 2487 2% 0% 7
9 PLOS COMPUTATIONAL BIOLOGY 2434 3% 0% 12
10 WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE 2294 1% 1% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 INTRACELLULAR DYNAMIC 157397 1% 100% 2 Search INTRACELLULAR+DYNAMIC Search INTRACELLULAR+DYNAMIC
2 NF KAPPA B SIGNAL TRANSDUCTION NETWORK 157397 1% 100% 2 Search NF+KAPPA+B+SIGNAL+TRANSDUCTION+NETWORK Search NF+KAPPA+B+SIGNAL+TRANSDUCTION+NETWORK
3 P53 MDM2 NEGATIVE FEEDBACK LOOP 157397 1% 100% 2 Search P53+MDM2+NEGATIVE+FEEDBACK+LOOP Search P53+MDM2+NEGATIVE+FEEDBACK+LOOP
4 P53 MDM2 SYSTEM 157397 1% 100% 2 Search P53+MDM2+SYSTEM Search P53+MDM2+SYSTEM
5 P53 PULSE 157397 1% 100% 2 Search P53+PULSE Search P53+PULSE
6 PARABOLIC HYPERBOLIC COUPLED MODEL 157397 1% 100% 2 Search PARABOLIC+HYPERBOLIC+COUPLED+MODEL Search PARABOLIC+HYPERBOLIC+COUPLED+MODEL
7 REPRESSILATORS 157397 1% 100% 2 Search REPRESSILATORS Search REPRESSILATORS
8 GENETIC OSCILLATIONS 118045 1% 50% 3 Search GENETIC+OSCILLATIONS Search GENETIC+OSCILLATIONS
9 P53 NETWORK 88532 1% 38% 3 Search P53+NETWORK Search P53+NETWORK
10 ACTIVATOR REPRESSOR SYSTEMS 78699 0% 100% 1 Search ACTIVATOR+REPRESSOR+SYSTEMS Search ACTIVATOR+REPRESSOR+SYSTEMS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 SUN, TZ , CUI, J , (2015) DYNAMICS OF P53 IN RESPONSE TO DNA DAMAGE: MATHEMATICAL MODELING AND PERSPECTIVE.PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY. VOL. 119. ISSUE 2. P. 175 -182 46 45% 1
2 CAO, Z , WANG, WD , (2015) ADVANCES IN THE RESEARCH OF P53 PULSES.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. VOL. 42. ISSUE 2. P. 147 -153 22 69% 1
3 ZAMBRANO, S , DE TOMA, I , PIFFER, A , BIANCHI, ME , AGRESTI, A , (2016) NF-KAPPA B OSCILLATIONS TRANSLATE INTO FUNCTIONALLY RELATED PATTERNS OF GENE EXPRESSION.ELIFE. VOL. 5. ISSUE . P. - 28 43% 3
4 LIU, B , YAN, SW , (2011) CELLULAR RESPONSE TO IRRADIATION.COMMUNICATIONS IN THEORETICAL PHYSICS. VOL. 55. ISSUE 5. P. 921-924 22 71% 1
5 ICHIKAWA, K , OHSHIMA, D , SAGARA, H , (2015) REGULATION OF SIGNAL TRANSDUCTION BY SPATIAL PARAMETERS: A CASE IN NF-KAPPA B OSCILLATION.IET SYSTEMS BIOLOGY. VOL. 9. ISSUE 2. P. 41 -51 43 31% 1
6 MOTHES, J , BUSSE, D , KOFAHL, B , WOLF, J , (2015) SOURCES OF DYNAMIC VARIABILITY IN NF-KAPPA B SIGNAL TRANSDUCTION: A MECHANISTIC MODEL.BIOESSAYS. VOL. 37. ISSUE 4. P. 452 -462 24 50% 6
7 BASAK, S , BEHAR, M , HOFFMANN, A , (2012) LESSONS FROM MATHEMATICALLY MODELING THE NF-KAPPA B PATHWAY.IMMUNOLOGICAL REVIEWS. VOL. 246. ISSUE . P. 221-238 28 42% 31
8 SUN, TZ , CUI, J , (2014) A PLAUSIBLE MODEL FOR BIMODAL P53 SWITCH IN DNA DAMAGE RESPONSE.FEBS LETTERS. VOL. 588. ISSUE 5. P. 815-821 24 51% 3
9 ZAMBRANO, S , BIANCHI, ME , AGRESTI, A , (2014) HIGH-THROUGHPUT ANALYSIS OF NF-KAPPA B DYNAMICS IN SINGLE CELLS REVEALS BASAL NUCLEAR LOCALIZATION OF NF-KAPPA B AND SPONTANEOUS ACTIVATION OF OSCILLATIONS.PLOS ONE. VOL. 9. ISSUE 3. P. - 17 68% 8
10 GAUDET, S , MILLER-JENSEN, K , (2016) REDEFINING SIGNALING PATHWAYS WITH AN EXPANDING SINGLE-CELL TOOLBOX.TRENDS IN BIOTECHNOLOGY. VOL. 34. ISSUE 6. P. 458 -469 27 39% 0

Classes with closest relation at Level 1


Rank Class id link
1 8965 CHEMICAL REACTION NETWORKS//MASS ACTION KINETICS//ULTRASENSITIVITY
2 1585 CHEMICAL MASTER EQUATION//STOCHASTIC GENE EXPRESSION//TAU LEAPING
3 1860 MDM2//MDMX//MDM4
4 500 NF KAPPA B//IKK//I KAPPA B
5 14368 SOMITOGENESIS//SEGMENTATION CLOCK//PRESOMITIC MESODERM
6 23966 GENETIC REGULATORY NETWORKS//GENETIC REGULATORY NETWORKS GRNS//DISCRETE TIME GENETIC REGULATORY NETWORK
7 12004 STRUCTURAL IDENTIFIABILITY//IDENTIFIABILITY//MODEL DISCRIMINATION
8 19765 A20//RNF11//ZINC FINGER PROTEIN A20
9 23185 WIP1//PPM1D//CELL CYCLE CONTROL TUMORIGENESIS GRP
10 31019 PDCD5//PROGRAMMED CELL DEATH 5//PROGRAMMED CELL DEATH 5 PDCD5

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