Class information for:
Level 1: IASPP//ASPP2//53BP2

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
31291 155 37.3 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
304 3       P53//RETINOBLASTOMA//MDM2 40663
936 2             P53//MDM2//P73 10991
31291 1                   IASPP//ASPP2//53BP2 155

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IASPP authKW 4733699 19% 83% 29
2 ASPP2 authKW 3859799 15% 85% 23
3 53BP2 authKW 1072571 5% 78% 7
4 ASPP authKW 840540 5% 53% 8
5 TP53BP2 authKW 788013 3% 100% 4
6 ASPP FAMILY MEMBERS authKW 394007 1% 100% 2
7 HEMATOL ONCOL RHEUMATOL IMMUNOL PULMOL address 394003 3% 50% 4
8 ASPP1 authKW 286545 3% 36% 4
9 LUDWIG CANC LTD address 218875 6% 11% 10
10 4 AMINO 2 TRIFLUOROMETHYL PHENYL RETINATE authKW 197003 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 1103 43% 0% 67
2 Oncology 701 35% 0% 55
3 Biochemistry & Molecular Biology 442 45% 0% 70
4 Biophysics 120 11% 0% 17
5 Genetics & Heredity 97 12% 0% 18
6 Developmental Biology 19 3% 0% 4
7 Substance Abuse 8 1% 0% 2
8 Hematology 5 3% 0% 4
9 Gastroenterology & Hepatology 2 2% 0% 3
10 Medicine, Research & Experimental 2 3% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEMATOL ONCOL RHEUMATOL IMMUNOL PULMOL 394003 3% 50% 4
2 LUDWIG CANC LTD 218875 6% 11% 10
3 AFFILIATED PEOPLES HOSP GUIYANG 197003 1% 100% 1
4 CANC UK RECEPTOR STRUCT GP 197003 1% 100% 1
5 CARDIOVASC RISK YOUNGER PERSONS 197003 1% 100% 1
6 CELL ENGN ANTIBODY 197003 1% 100% 1
7 GENOTOXCIOL TUMEURS 197003 1% 100% 1
8 GRPE RECH SYST NERVEUX CENT 197003 1% 100% 1
9 INVEST PATOL HEPAT 197003 1% 100% 1
10 MEDSICKKIDS 197003 1% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL DEATH AND DIFFERENTIATION 1551 3% 0% 5
2 CELL DEATH & DISEASE 1332 3% 0% 4
3 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1051 1% 0% 2
4 ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA 629 1% 0% 1
5 ONCOGENE 526 5% 0% 7
6 FRONTIERS OF HORMONE RESEARCH 441 1% 0% 1
7 JOURNAL OF HARD TISSUE BIOLOGY 439 1% 0% 1
8 GENES TO CELLS 409 1% 0% 2
9 DNA RESEARCH 308 1% 0% 1
10 DEVELOPMENTAL CELL 303 1% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 IASPP 4733699 19% 83% 29 Search IASPP Search IASPP
2 ASPP2 3859799 15% 85% 23 Search ASPP2 Search ASPP2
3 53BP2 1072571 5% 78% 7 Search 53BP2 Search 53BP2
4 ASPP 840540 5% 53% 8 Search ASPP Search ASPP
5 TP53BP2 788013 3% 100% 4 Search TP53BP2 Search TP53BP2
6 ASPP FAMILY MEMBERS 394007 1% 100% 2 Search ASPP+FAMILY+MEMBERS Search ASPP+FAMILY+MEMBERS
7 ASPP1 286545 3% 36% 4 Search ASPP1 Search ASPP1
8 4 AMINO 2 TRIFLUOROMETHYL PHENYL RETINATE 197003 1% 100% 1 Search 4+AMINO+2+TRIFLUOROMETHYL+PHENYL+RETINATE Search 4+AMINO+2+TRIFLUOROMETHYL+PHENYL+RETINATE
9 A34 197003 1% 100% 1 Search A34 Search A34
10 APOPTOSIS STIMULATING OF P53 PROTEIN 2 197003 1% 100% 1 Search APOPTOSIS+STIMULATING+OF+P53+PROTEIN+2 Search APOPTOSIS+STIMULATING+OF+P53+PROTEIN+2

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 LI, Y , AHMAD, A , SARKAR, FH , (2015) ASPP AND IASPP: IMPLICATION IN CANCER DEVELOPMENT AND PROGRESSION.CELLULAR AND MOLECULAR BIOLOGY. VOL. 61. ISSUE 6. P. 2 -8 52 63% 15
2 IOSUB-AMIR, A , FRIEDLER, A , (2014) PROTEIN-PROTEIN INTERACTIONS OF ASPP2: AN EMERGING THERAPEUTIC TARGET.MEDCHEMCOMM. VOL. 5. ISSUE 10. P. 1435 -1443 53 54% 2
3 VAN HOOK, K , WANG, ZP , CHEN, DX , NOLD, C , ZHU, ZY , ANUR, P , LEE, HJ , YU, ZY , SHEPPARD, B , DAI, MS , ET AL (2017) DELTA N-ASPP2, A NOVEL ISOFORM OF THE ASPP2 TUMOR SUPPRESSOR, PROMOTES CELLULAR SURVIVAL.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. VOL. 482. ISSUE 4. P. 1271 -1277 27 75% 0
4 KAMPA, KM , BONIN, M , LOPEZ, CD , (2009) NEW INSIGHTS INTO THE EXPANDING COMPLEXITY OF THE TUMOR SUPPRESSOR ASPP2.CELL CYCLE. VOL. 8. ISSUE 18. P. 2871 -2876 35 65% 17
5 AMIR, AI , VAN ROSMALEN, M , MAYER, G , LEBENDIKER, M , DANIELI, T , FRIEDLER, A , (2015) HIGHLY HOMOLOGOUS PROTEINS EXERT OPPOSITE BIOLOGICAL ACTIVITIES BY USING DIFFERENT INTERACTION INTERFACES.SCIENTIFIC REPORTS. VOL. 5. ISSUE . P. - 30 55% 2
6 CHEN, Y , YAN, WX , HE, SQ , CHEN, JC , CHEN, D , ZHANG, ZQ , LIU, ZG , DING, XQ , WANG, AX , (2014) IN VITRO EFFECT OF IASPP ON CELL GROWTH OF ORAL TONGUE SQUAMOUS CELL CARCINOMA.CHINESE JOURNAL OF CANCER RESEARCH. VOL. 26. ISSUE 4. P. 382 -390 21 72% 2
7 LIU, ZZ , ZHANG, X , HUANG, DH , LIU, Y , ZHANG, XZ , LIU, LJ , LI, G , DAI, YZ , TAN, HL , XIAO, JY , ET AL (2012) ELEVATED EXPRESSION OF IASPP IN HEAD AND NECK SQUAMOUS CELL CARCINOMA AND ITS CLINICAL SIGNIFICANCE.MEDICAL ONCOLOGY. VOL. 29. ISSUE 5. P. 3381-3388 20 67% 17
8 SULLIVAN, A , LU, X , (2007) ASPP: A NEW FAMILY OF ONCOGENES AND TUMOUR SUPPRESSOR GENES.BRITISH JOURNAL OF CANCER. VOL. 96. ISSUE 2. P. 196 -200 22 56% 105
9 QIU, S , CAI, Y , GAO, X , GU, SZ , LIU, ZJ , (2015) A SMALL PEPTIDE DERIVED FROM P53 LINKER REGION CAN RESUME THE APOPTOTIC ACTIVITY OF P53 BY SEQUESTERING IASPP WITH P53.CANCER LETTERS. VOL. 356. ISSUE 2. P. 910 -917 16 70% 4
10 WANG, LL , XU, Z , PENG, Y , LI, LC , WU, XL , (2015) DOWNREGULATION OF INHIBITOR OF APOPTOSIS-STIMULATING PROTEIN OF P53 INHIBITS PROLIFERATION AND PROMOTES APOPTOSIS OF GASTRIC CANCER CELLS.MOLECULAR MEDICINE REPORTS. VOL. 12. ISSUE 2. P. 1653 -1658 16 73% 1

Classes with closest relation at Level 1


Rank Class id link
1 8010 MUTANT P53//PRIMA 1//CP 31398
2 1860 MDM2//MDMX//MDM4
3 4381 P73//P63//EEC SYNDROME
4 32594 NUCLEOSTEMIN//GNL3L//GUANINE NUCLEOTIDE BINDING PROTEIN LIKE 3
5 36588 PELGER HUET ANOMALY//PELGER HUET//PSEUDO PELGER HUET ANOMALY
6 37254 3D SPHEROID ASSAYS//BORTENAT//EARLY EVENTS IN BREAST TUMORIGENESIS
7 5305 YAP//HIPPO PATHWAY//TAZ
8 36673 MYOTROPHIN//V 1 PROTEIN//S MYOTROPHIN
9 36779 CDK11P58//PITSLRE//CDK11
10 9053 P53 POLYMORPHISM//P53 CODON 72//CODON 72

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