Class information for:
Level 1: HUMAN MOL GENET PROGRAM//CFTR GENE EXPRESSION//CFTR PROMOTER

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
36383 82 41.3 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
597 3       CYSTIC FIBROSIS//CFTR//JOURNAL OF CYSTIC FIBROSIS 14714
542 2             CYSTIC FIBROSIS//CFTR//JOURNAL OF CYSTIC FIBROSIS 14714
36383 1                   HUMAN MOL GENET PROGRAM//CFTR GENE EXPRESSION//CFTR PROMOTER 82

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN MOL GENET PROGRAM address 1675711 22% 25% 18
2 CFTR GENE EXPRESSION authKW 496513 2% 67% 2
3 CFTR PROMOTER authKW 496513 2% 67% 2
4 LURIE CHILDRENS address 418931 4% 38% 3
5 ASZ1 authKW 372386 1% 100% 1
6 BAC INTEGRATION authKW 372386 1% 100% 1
7 BIOL ENCEPHALOPATHIES SPONGIFORMES TRANSMISSI address 372386 1% 100% 1
8 CAUDAL HOMEOBOX PROTEIN 2 CDX2 authKW 372386 1% 100% 1
9 CFTR CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE authKW 372386 1% 100% 1
10 CFTR PROMOTER VARIANT authKW 372386 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 756 77% 0% 63
2 Genetics & Heredity 502 33% 0% 27
3 Cell Biology 76 17% 0% 14
4 Respiratory System 56 7% 0% 6
5 Biotechnology & Applied Microbiology 32 10% 0% 8
6 Medicine, Research & Experimental 23 7% 0% 6
7 Biophysics 16 6% 0% 5
8 Medical Laboratory Technology 3 1% 0% 1
9 Reproductive Biology 2 1% 0% 1
10 Developmental Biology 1 1% 0% 1

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN MOL GENET PROGRAM 1675711 22% 25% 18
2 LURIE CHILDRENS 418931 4% 38% 3
3 BIOL ENCEPHALOPATHIES SPONGIFORMES TRANSMISSI 372386 1% 100% 1
4 CHILDRENS MEM HUMAN MOL GENET PROGRAM 372386 1% 100% 1
5 EUDOWOOOD PEDIAT P SCI 372386 1% 100% 1
6 GENET HUMAINE UNITE PROPRE RECH 1142 372386 1% 100% 1
7 HUMAN MOL GENET PROGRAM PEDIAT 372386 1% 100% 1
8 LUIRE CHILDRENS 372386 1% 100% 1
9 PROLIFERAT DIFFERENTIAT CELLULAIRE 372386 1% 100% 1
10 SFR SCINBIO RU B TETAB FRANCAIS SANG BRETAG 372386 1% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EPIGENETICS 5815 2% 1% 2
2 HUMAN MOLECULAR GENETICS 3094 11% 0% 9
3 JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 1219 4% 0% 3
4 GENES 878 1% 0% 1
5 NUCLEIC ACIDS RESEARCH 758 11% 0% 9
6 GENOMICS 716 5% 0% 4
7 AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 659 4% 0% 3
8 BIOCHEMICAL JOURNAL 454 7% 0% 6
9 GENE THERAPY 378 2% 0% 2
10 BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS 354 1% 0% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CFTR GENE EXPRESSION 496513 2% 67% 2 Search CFTR+GENE+EXPRESSION Search CFTR+GENE+EXPRESSION
2 CFTR PROMOTER 496513 2% 67% 2 Search CFTR+PROMOTER Search CFTR+PROMOTER
3 ASZ1 372386 1% 100% 1 Search ASZ1 Search ASZ1
4 BAC INTEGRATION 372386 1% 100% 1 Search BAC+INTEGRATION Search BAC+INTEGRATION
5 CAUDAL HOMEOBOX PROTEIN 2 CDX2 372386 1% 100% 1 Search CAUDAL+HOMEOBOX+PROTEIN+2+CDX2 Search CAUDAL+HOMEOBOX+PROTEIN+2+CDX2
6 CFTR CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE 372386 1% 100% 1 Search CFTR+CYSTIC+FIBROSIS+TRANSMEMBRANE+CONDUCTANCE Search CFTR+CYSTIC+FIBROSIS+TRANSMEMBRANE+CONDUCTANCE
7 CFTR PROMOTER VARIANT 372386 1% 100% 1 Search CFTR+PROMOTER+VARIANT Search CFTR+PROMOTER+VARIANT
8 CORTACTIN BINDING PROTEIN 2 CTTNBP2 372386 1% 100% 1 Search CORTACTIN+BINDING+PROTEIN+2+CTTNBP2 Search CORTACTIN+BINDING+PROTEIN+2+CTTNBP2
9 DNASE I HYPERSENSITIVE SITE DHS 372386 1% 100% 1 Search DNASE+I+HYPERSENSITIVE+SITE+DHS Search DNASE+I+HYPERSENSITIVE+SITE+DHS
10 ENHANCERPROMOTER INTERACTIONS 372386 1% 100% 1 Search ENHANCERPROMOTER+INTERACTIONS Search ENHANCERPROMOTER+INTERACTIONS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 GOSALIA, N , HARRIS, A , (2015) CHROMATIN DYNAMICS IN THE REGULATION OF CFTR EXPRESSION.GENES. VOL. 6. ISSUE 3. P. 543 -558 40 44% 3
2 MCCARTHY, VA , HARRIS, A , (2005) THE CFTR GENE AND REGULATION OF ITS EXPRESSION.PEDIATRIC PULMONOLOGY. VOL. 40. ISSUE 1. P. 1-8 31 53% 36
3 BERGOUGNOUX, A , RIVALS, I , LIQUORI, A , RAYNAL, C , VARILH, J , MAGALHAES, M , PEREZ, MJ , BIGI, N , GEORGES, MD , CHIRON, R , ET AL (2014) A BALANCE BETWEEN ACTIVATING AND REPRESSIVE HISTONE MODIFICATIONS REGULATES CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) EXPRESSION IN VIVO.EPIGENETICS. VOL. 9. ISSUE 7. P. 1007 -1017 18 53% 2
4 OTT, CJ , BISCHOF, JM , UNTI, KM , GILLEN, AE , LEIR, SH , HARRIS, A , (2012) NUCLEOSOME OCCUPANCY REVEALS REGULATORY ELEMENTS OF THE CFTR PROMOTER.NUCLEIC ACIDS RESEARCH. VOL. 40. ISSUE 2. P. 625 -637 22 44% 6
5 VIART, V , BERGOUGNOUX, A , BONINI, J , VARILH, J , CHIRON, R , TABARY, O , MOLINARI, N , CLAUSTRES, M , TAULAN-CADARS, M , (2015) TRANSCRIPTION FACTORS AND MIRNAS THAT REGULATE FETAL TO ADULT CFTR EXPRESSION CHANGE ARE NEW TARGETS FOR CYSTIC FIBROSIS.EUROPEAN RESPIRATORY JOURNAL. VOL. 45. ISSUE 1. P. 116 -128 21 40% 5
6 LEWANDOWSKA, MA , COSTA, FF , BISCHOF, JM , WILLIAMS, SH , SOARES, MB , HARRIS, A , (2010) MULTIPLE MECHANISMS INFLUENCE REGULATION OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR GENE PROMOTER.AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. VOL. 43. ISSUE 3. P. 334-341 21 48% 11
7 ULATOWSKI, LM , WHITMORE, KL , ROMIGH, T , VANDERWYDEN, AS , SATINOVER, SM , DRUMM, ML , (2004) STRAIN-SPECIFIC VARIANTS OF THE MOUSE CFTR PROMOTER REGION REVEAL TRANSCRIPTIONAL REGULATORY ELEMENTS.HUMAN MOLECULAR GENETICS. VOL. 13. ISSUE 17. P. 1933-1941 19 63% 5
8 WILLIAMS, SH , MOUCHEL, N , HARRIS, A , (2003) A COMPARATIVE GENOMIC ANALYSIS OF THE COW, PIG, AND HUMAN CFTR GENES IDENTIFIES POTENTIAL INTRONIC REGULATORY ELEMENTS.GENOMICS. VOL. 81. ISSUE 6. P. 628-639 12 86% 7
9 MOISAN, S , BERLIVET, S , KA, C , LE GAC, G , DOSTIE, J , FEREC, C , (2016) ANALYSIS OF LONG-RANGE INTERACTIONS IN PRIMARY HUMAN CELLS IDENTIFIES COOPERATIVE CFTR REGULATORY ELEMENTS.NUCLEIC ACIDS RESEARCH. VOL. 44. ISSUE 6. P. 2564 -2576 22 34% 0
10 OTT, CJ , SUSZKO, M , BLACKLEDGE, NP , WRIGHT, JE , CRAWFORD, GE , HARRIS, A , (2009) A COMPLEX INTRONIC ENHANCER REGULATES EXPRESSION OF THE CFTR GENE BY DIRECT INTERACTION WITH THE PROMOTER.JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. VOL. 13. ISSUE 4. P. 680 -692 19 40% 19

Classes with closest relation at Level 1


Rank Class id link
1 1681 CYSTIC FIBROSIS//CFTR GENE//SWEAT TEST
2 2342 CFTR//CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR//CYSTIC FIBROSIS
3 16206 GENE MED GRP//GENEMED GRP//EXPT TREATMENT CYST FIBROSIS
4 32766 EPITHELIAL CELL BIOL//JOINT HUMAN REPROD RELATED DIS//BAK FOONG PILLS
5 24340 HUMAN ARTIFICIAL CHROMOSOME//REGENERAT MED BIOFUNCT//CHROMOSOME ENGN
6 23621 PANCREATIC DUCT//PANCREATIC DUCT EPITHELIAL CELLS//PANCREATIC DUCT CELLS
7 28334 SMAR1//CUTL1//CCAAT DISPLACEMENT PROTEIN
8 11594 CTCF//CONTROL GENET PROC//SUHW
9 3065 CHROMOSOME TERRITORY//NUCLEAR ARCHITECTURE//NUCLEAR ORGANIZATION
10 11241 CYSTIC FIBROSIS//INFECT CYST FIBROSIS UNIT//ANTI INFLAMMATORY AGENTS ADMINISTRATION DOSAGE ADVERSE EFFECTS

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