Class information for:
Level 1: INDOLEAMINE 2 3 DIOXYGENASE//INDOLEAMINE 2//IDO

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5931 1557 45.3 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
631 3       KYNURENINE//NEOPTERIN//INDOLEAMINE 2 3 DIOXYGENASE 12928
2074 2             KYNURENINE//NEOPTERIN//INDOLEAMINE 2 3 DIOXYGENASE 5255
5931 1                   INDOLEAMINE 2 3 DIOXYGENASE//INDOLEAMINE 2//IDO 1557

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INDOLEAMINE 2 3 DIOXYGENASE authKW 3653047 20% 59% 316
2 INDOLEAMINE 2 authKW 989639 5% 62% 81
3 IDO authKW 983826 7% 45% 112
4 3 DIOXYGENASE authKW 800682 4% 58% 70
5 KYNURENINE authKW 482210 8% 19% 128
6 INDOLEAMINE 2 3 DIOXYGENASE IDO authKW 323306 2% 63% 26
7 TRYPTOPHAN authKW 253398 13% 7% 197
8 1 METHYL TRYPTOPHAN authKW 245120 1% 83% 15
9 INDOLEAMINE DIOXYGENASE authKW 244359 1% 69% 18
10 IDO1 authKW 226680 1% 68% 17

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 6872 32% 0% 506
2 Biochemistry & Molecular Biology 831 23% 0% 353
3 Medicine, Research & Experimental 729 9% 0% 142
4 Oncology 585 12% 0% 186
5 Cell Biology 377 10% 0% 154
6 Chemistry, Medicinal 257 5% 0% 71
7 Hematology 253 5% 0% 73
8 Transplantation 249 3% 0% 47
9 Allergy 127 2% 0% 24
10 Biophysics 96 4% 0% 62

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INFORMAT CLIN MED 191199 2% 30% 32
2 CENT BLOOD TRANSFUS IMMUNOL 137588 1% 35% 20
3 PROGRAM MOL IMMUNOL 103862 1% 38% 14
4 MOL IMMUNOPATHOL UNIT 66154 1% 19% 18
5 BIOCHEM PL SCI 58830 0% 100% 3
6 PL SCI BIOCHEM 58830 0% 100% 3
7 AUSTRALIAN CATARACT FDN 57119 1% 22% 13
8 LONGEV SCI 40734 2% 9% 24
9 INTERNAL MEDKALAFONG HOSP 39220 0% 100% 2
10 MITOCHONDRIA SIGNALING MED 39220 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CURRENT DRUG METABOLISM 3486 1% 1% 14
2 ONCOIMMUNOLOGY 2933 1% 1% 12
3 JOURNAL OF IMMUNOLOGY 2355 5% 0% 82
4 JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 2205 1% 1% 16
5 JOURNAL OF INTERFERON RESEARCH 1620 1% 1% 9
6 PTERIDINES 1204 0% 1% 5
7 JOURNAL OF REPRODUCTIVE IMMUNOLOGY 970 1% 1% 10
8 TRANSPLANT IMMUNOLOGY 832 0% 1% 7
9 FRONTIERS IN IMMUNOLOGY 797 1% 0% 11
10 IMMUNOLOGY LETTERS 773 1% 0% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 INDOLEAMINE 2 3 DIOXYGENASE 3653047 20% 59% 316 Search INDOLEAMINE+2+3+DIOXYGENASE Search INDOLEAMINE+2+3+DIOXYGENASE
2 INDOLEAMINE 2 989639 5% 62% 81 Search INDOLEAMINE+2 Search INDOLEAMINE+2
3 IDO 983826 7% 45% 112 Search IDO Search IDO
4 3 DIOXYGENASE 800682 4% 58% 70 Search 3+DIOXYGENASE Search 3+DIOXYGENASE
5 KYNURENINE 482210 8% 19% 128 Search KYNURENINE Search KYNURENINE
6 INDOLEAMINE 2 3 DIOXYGENASE IDO 323306 2% 63% 26 Search INDOLEAMINE+2+3+DIOXYGENASE+IDO Search INDOLEAMINE+2+3+DIOXYGENASE+IDO
7 TRYPTOPHAN 253398 13% 7% 197 Search TRYPTOPHAN Search TRYPTOPHAN
8 1 METHYL TRYPTOPHAN 245120 1% 83% 15 Search 1+METHYL+TRYPTOPHAN Search 1+METHYL+TRYPTOPHAN
9 INDOLEAMINE DIOXYGENASE 244359 1% 69% 18 Search INDOLEAMINE+DIOXYGENASE Search INDOLEAMINE+DIOXYGENASE
10 IDO1 226680 1% 68% 17 Search IDO1 Search IDO1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 YEUNG, AWS , TERENTIS, AC , KING, NJC , THOMAS, SR , (2015) ROLE OF INDOLEAMINE 2,3-DIOXYGENASE IN HEALTH AND DISEASE.CLINICAL SCIENCE. VOL. 129. ISSUE 7. P. 601 -672 385 69% 13
2 TAN, PH , BHARATH, AK , (2009) MANIPULATION OF INDOLEAMINE 2,3 DIOXYGENASE; A NOVEL THERAPEUTIC TARGET FOR TREATMENT OF DISEASES.EXPERT OPINION ON THERAPEUTIC TARGETS. VOL. 13. ISSUE 8. P. 987 -1012 151 68% 19
3 JOHNSON, TS , MUNN, DH , (2012) HOST INDOLEAMINE 2,3-DIOXYGENASE: CONTRIBUTION TO SYSTEMIC ACQUIRED TUMOR TOLERANCE.IMMUNOLOGICAL INVESTIGATIONS. VOL. 41. ISSUE 6-7. P. 765 -797 129 66% 21
4 ROHRIG, UF , MAJJIGAPU, SR , VOGEL, P , ZOETE, V , MICHIEIN, O , (2015) CHALLENGES IN THE DISCOVERY OF INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) INHIBITORS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 58. ISSUE 24. P. 9421 -9437 86 77% 15
5 MELLOR, AL , MUNN, DH , (2004) IDO EXPRESSION BY DENDRITIC CELLS: TOLERANCE AND TRYPTOPHAN CATABOLISM.NATURE REVIEWS IMMUNOLOGY. VOL. 4. ISSUE 10. P. 762-774 82 60% 1161
6 DI PUCCHIO, T , DANESE, S , DE CRISTOFARO, R , RUTELLA, S , (2010) INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE: A REVIEW OF NOVEL PATENTED LEAD COMPOUNDS.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 20. ISSUE 2. P. 229-250 121 72% 19
7 LIU, X , NEWTON, RC , FRIEDMAN, SM , SCHERLE, PA , (2009) INDOLEAMINE 2,3-DIOXYGENASE, AN EMERGING TARGET FOR ANTI-CANCER THERAPY.CURRENT CANCER DRUG TARGETS. VOL. 9. ISSUE 8. P. 938-952 94 93% 24
8 MCGAHA, TL , HUANG, L , LEMOS, H , METZ, R , MAUTINO, M , PRENDERGAST, GC , MELLOR, AL , (2012) AMINO ACID CATABOLISM: A PIVOTAL REGULATOR OF INNATE AND ADAPTIVE IMMUNITY.IMMUNOLOGICAL REVIEWS. VOL. 249. ISSUE . P. 135-157 115 66% 24
9 JOHNSON, BA , BABAN, B , MELLOR, AL , (2009) TARGETING THE IMMUNOREGULATORY INDOLEAMINE 2,3 DIOXYGENASE PATHWAY IN IMMUNOTHERAPY.IMMUNOTHERAPY. VOL. 1. ISSUE 4. P. 645-661 97 84% 33
10 GONZALEZ, A , VARO, N , ALEGRE, E , DIAZ, A , MELERO, I , (2008) IMMUNOSUPPRESSION ROUTED VIA THE KYNURENINE PATHWAY: A BIOCHEMICAL AND PATHOPHYSIOLOGIC APPROACH.ADVANCES IN CLINICAL CHEMISTRY, VOL 45. VOL. 45. ISSUE . P. 155 -197 120 66% 22

Classes with closest relation at Level 1


Rank Class id link
1 5001 KYNURENIC ACID//KYNURENINE//QUINOLINIC ACID
2 10585 NEOPTERIN//PTERIDINES//MED CHEM BIOCHEM FRITZ PREGL STR 3
3 35146 TNFRSF21//ARA267 ALPHA//BIO THER EUT DISCOVERY
4 12670 DENDRITIC CELLS//TOLEROGENIC DENDRITIC CELLS//THOMAS E STARZL TRANSPLANTAT
5 17202 HUMAN CULTU//LIFE STYLE STUDIES//PELLAGRA
6 12735 PLASMACYTOID DENDRITIC CELLS//BDCA 4//PDC
7 7415 MYELOID DERIVED SUPPRESSOR CELLS//MDSC//MYELOID DERIVED SUPPRESSOR CELLS MDSC
8 4080 REGULATORY T CELLS//FOXP3//TUMOR INFILTRATING LYMPHOCYTES
9 12458 MICROBIAL TRANSLOCATION//IMMUNE ACTIVATION//HUMAN IMMUNOL SECT
10 3846 BRAIN BEHAVIOR AND IMMUNITY//DEPRESSION//PSYCHONEUROIMMUNOLOGY

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