Class information for:
Level 1: KYNURENIC ACID//KYNURENINE//QUINOLINIC ACID

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5001 1690 45.1 76%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
631 3       KYNURENINE//NEOPTERIN//INDOLEAMINE 2 3 DIOXYGENASE 12928
2074 2             KYNURENINE//NEOPTERIN//INDOLEAMINE 2 3 DIOXYGENASE 5255
5001 1                   KYNURENIC ACID//KYNURENINE//QUINOLINIC ACID 1690

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 KYNURENIC ACID authKW 3998597 21% 64% 347
2 KYNURENINE authKW 2021421 16% 41% 273
3 QUINOLINIC ACID authKW 1892935 15% 42% 252
4 KYNURENINE PATHWAY authKW 1349305 7% 66% 114
5 KYNURENINE AMINOTRANSFERASE authKW 920832 3% 88% 58
6 3 HYDROXYKYNURENINE authKW 763123 4% 68% 62
7 PHYSIOL ANAT NEUROSCI address 328558 3% 37% 49
8 KYNURENINE 3 MONOOXYGENASE authKW 254495 1% 78% 18
9 KYNURENINASE authKW 192699 1% 67% 16
10 MARYLAND PSYCHIAT address 190196 6% 11% 100

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 10447 46% 0% 776
2 Pharmacology & Pharmacy 1293 18% 0% 307
3 Biochemistry & Molecular Biology 1098 24% 0% 413
4 Clinical Neurology 611 10% 0% 164
5 Psychiatry 304 6% 0% 100
6 Medicine, Research & Experimental 228 6% 0% 93
7 Chemistry, Analytical 131 5% 0% 90
8 Chemistry, Medicinal 124 3% 0% 56
9 Biochemical Research Methods 87 3% 0% 57
10 Physiology 69 3% 0% 55

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHYSIOL ANAT NEUROSCI 328558 3% 37% 49
2 MARYLAND PSYCHIAT 190196 6% 11% 100
3 AMINOACIDOS EXCITADO 98331 1% 26% 21
4 RAY WILLIAMS BIOMED MASS SPE OMETRY IL 95078 1% 53% 10
5 PSYCHIAT INFLAMMAT PROGRAM 81296 0% 75% 6
6 ALBERT SZENT GYORGYI CLIN 74430 2% 14% 29
7 MTA SZTE NEUROSCI GRP 70504 1% 35% 11
8 MED MARYLAND PSYCHIAT 68090 0% 54% 7
9 NEUROL GRP 62130 1% 20% 17
10 AUSTRALASIAN 56272 1% 35% 9

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF NEURAL TRANSMISSION 10577 3% 1% 49
2 JOURNAL OF NEUROCHEMISTRY 4915 4% 0% 76
3 EXPERIMENTAL NEUROLOGY 2604 2% 0% 37
4 NEUROSCIENCE LETTERS 2364 4% 0% 65
5 NEUROPHARMACOLOGY 2049 2% 0% 33
6 PHARMACOLOGICAL REPORTS 1952 1% 1% 14
7 BRAIN RESEARCH 1769 4% 0% 70
8 ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 1683 2% 0% 40
9 FARMAKOLOGIYA I TOKSIKOLOGIYA 1471 1% 1% 10
10 REDOX REPORT 1220 0% 1% 8

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 KYNURENIC ACID 3998597 21% 64% 347 Search KYNURENIC+ACID Search KYNURENIC+ACID
2 KYNURENINE 2021421 16% 41% 273 Search KYNURENINE Search KYNURENINE
3 QUINOLINIC ACID 1892935 15% 42% 252 Search QUINOLINIC+ACID Search QUINOLINIC+ACID
4 KYNURENINE PATHWAY 1349305 7% 66% 114 Search KYNURENINE+PATHWAY Search KYNURENINE+PATHWAY
5 KYNURENINE AMINOTRANSFERASE 920832 3% 88% 58 Search KYNURENINE+AMINOTRANSFERASE Search KYNURENINE+AMINOTRANSFERASE
6 3 HYDROXYKYNURENINE 763123 4% 68% 62 Search 3+HYDROXYKYNURENINE Search 3+HYDROXYKYNURENINE
7 KYNURENINE 3 MONOOXYGENASE 254495 1% 78% 18 Search KYNURENINE+3+MONOOXYGENASE Search KYNURENINE+3+MONOOXYGENASE
8 KYNURENINASE 192699 1% 67% 16 Search KYNURENINASE Search KYNURENINASE
9 KYNURENINE 3 HYDROXYLASE 150551 1% 83% 10 Search KYNURENINE+3+HYDROXYLASE Search KYNURENINE+3+HYDROXYLASE
10 XANTHURENIC ACID 141007 1% 35% 22 Search XANTHURENIC+ACID Search XANTHURENIC+ACID

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 SCHWARCZ, R , BRUNO, JP , MUCHOWSKI, PJ , WU, HQ , (2012) KYNURENINES IN THE MAMMALIAN BRAIN: WHEN PHYSIOLOGY MEETS PATHOLOGY.NATURE REVIEWS NEUROSCIENCE. VOL. 13. ISSUE 7. P. 465 -477 147 76% 261
2 LOVELACE, MD , VARNEY, B , SUNDARAM, G , LENNON, MJ , LIM, CK , JACOBS, K , GUILLEMIN, GJ , BREW, BJ , (2017) RECENT EVIDENCE FOR AN EXPANDED ROLE OF THE KYNURENINE PATHWAY OF TRYPTOPHAN METABOLISM IN NEUROLOGICAL DISEASES.NEUROPHARMACOLOGY. VOL. 112. ISSUE . P. 373 -388 82 50% 4
3 FUJIGAKI, H , YAMAMOTO, Y , SAITO, K , (2017) L-TRYPTOPHAN-KYNURENINE PATHWAY ENZYMES ARE THERAPEUTIC TARGET FOR NEUROPSYCHIATRIC DISEASES: FOCUS ON CELL TYPE DIFFERENCES.NEUROPHARMACOLOGY. VOL. 112. ISSUE . P. 264 -274 104 65% 1
4 VECSEI, L , SZALARDY, L , FULOP, F , TOLDI, J , (2013) KYNURENINES IN THE CNS: RECENT ADVANCES AND NEW QUESTIONS.NATURE REVIEWS DRUG DISCOVERY. VOL. 12. ISSUE 1. P. 64 -82 122 57% 107
5 STONE, TW , (2001) KYNURENINES IN THE CNS: FROM ENDOGENOUS OBSCURITY TO THERAPEUTIC IMPORTANCE.PROGRESS IN NEUROBIOLOGY. VOL. 64. ISSUE 2. P. 185 -218 188 61% 192
6 ERHARDT, S , SCHWIELER, L , IMBEAULT, S , ENGBERG, G , (2017) THE KYNURENINE PATHWAY IN SCHIZOPHRENIA AND BIPOLAR DISORDER.NEUROPHARMACOLOGY. VOL. 112. ISSUE . P. 297 -306 78 55% 2
7 NOTARANGELO, FM , POCIVAYSEK, A , (2017) ELEVATED KYNURENINE PATHWAY METABOLISM DURING NEURODEVELOPMENT: IMPLICATIONS FOR BRAIN AND BEHAVIOR.NEUROPHARMACOLOGY. VOL. 112. ISSUE . P. 275 -285 78 53% 2
8 ZADORI, D , VERES, G , SZALARDY, L , KLIVENYI, P , FULOP, F , TOLDI, J , VECSEI, L , (2016) INHIBITORS OF THE KYNURENINE PATHWAY AS NEUROTHERAPEUTICS: A PATENT REVIEW (2012-2015).EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 26. ISSUE 7. P. 815 -832 107 80% 0
9 O'FARRELL, K , HARKIN, A , (2017) STRESS-RELATED REGULATION OF THE KYNURENINE PATHWAY: RELEVANCE TO NEUROPSYCHIATRIC AND DEGENERATIVE DISORDERS.NEUROPHARMACOLOGY. VOL. 112. ISSUE . P. 307 -323 100 48% 1
10 OCAMPO, JR , HUITRON, RL , GONZALEZ-ESQUIVEL, D , UGALDE-MUNIZ, P , JIMENEZ-ANGUIANO, A , PINEDA, B , PEDRAZA-CHAVERRI, J , RIOS, C , DE LA CRUZ, VP , (2014) KYNURENINES WITH NEUROACTIVE AND REDOX PROPERTIES: RELEVANCE TO AGING AND BRAIN DISEASES.OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. VOL. . ISSUE . P. - 130 60% 6

Classes with closest relation at Level 1


Rank Class id link
1 5931 INDOLEAMINE 2 3 DIOXYGENASE//INDOLEAMINE 2//IDO
2 17202 HUMAN CULTU//LIFE STYLE STUDIES//PELLAGRA
3 19391 3 NITROPROPIONIC ACID//3 NP//MITOCHONDRIAL TOXIN
4 36341 DEMENTIA SERV//COULOMETRIC MULTIELECTRODE ARRAY SYSTEM//CUSTOMER PLICAT SUPPORT
5 26108 BIOCHEM TECHNOL SCI TECHNOL//GPR35//RESONANT WAVEGUIDE GRATING BIOSENSOR
6 5639 HOMOCYSTEATE//2 AMINO 4 PHOSPHONOBUTANOIC ACID//BETA P CHLOROPHENYLGLUTAMATE
7 6033 ARCAINE//POLYAMINES//SPERMINE
8 3846 BRAIN BEHAVIOR AND IMMUNITY//DEPRESSION//PSYCHONEUROIMMUNOLOGY
9 33692 HEMISPHERIC CHEMICAL DOMINANCE//MEMBRANE NA K ATPASE//DOLICHOL
10 33743 BRAIN CRYOSECTION//CALCIUM STRUCTURES//CHLORELLA VULGARIS CULTURE

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