Class information for:
Level 2: HEDGEHOG//GLI//CILIOPATHY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1658 6876 45.3 85%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
642 3       POLYCYSTIC KIDNEY DISEASE//AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE//HEDGEHOG 12305
1658 2             HEDGEHOG//GLI//CILIOPATHY 6876
613 1                   HEDGEHOG//GLI//SMOOTHENED 3247
1635 1                   JOUBERT SYNDROME//CILIOPATHY//BARDET BIEDL SYNDROME 2561
15893 1                   ELLIS VAN CREVELD SYNDROME//JEUNE SYNDROME//ORAL FACIAL DIGITAL SYNDROME 685
30188 1                   TUBBY//TULP1//ORF PHAGE DISPLAY 173
32237 1                   ALSTROM SYNDROME//ALMS1//ALMS1 GENE 142
37024 1                   RAB23//CARPENTER SYNDROME//ACROCEPHALOPOLYSYNDACTYLY TYPE II 68

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEDGEHOG authKW 985813 8% 42% 535
2 GLI authKW 564292 3% 71% 179
3 CILIOPATHY authKW 532835 3% 68% 176
4 SMOOTHENED authKW 516443 2% 73% 160
5 HEDGEHOG SIGNALING authKW 515556 3% 62% 187
6 SONIC HEDGEHOG authKW 466858 5% 31% 344
7 JOUBERT SYNDROME authKW 450235 2% 80% 127
8 PRIMARY CILIA authKW 448707 2% 62% 164
9 BARDET BIEDL SYNDROME authKW 431072 2% 75% 130
10 CYCLOPAMINE authKW 400544 2% 65% 138

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Developmental Biology 19373 11% 1% 753
2 Cell Biology 16292 26% 0% 1783
3 Genetics & Heredity 12792 19% 0% 1297
4 Oncology 3258 13% 0% 902
5 Biochemistry & Molecular Biology 2632 20% 0% 1378
6 Pediatrics 1183 6% 0% 379
7 Urology & Nephrology 733 4% 0% 259
8 Ophthalmology 402 3% 0% 187
9 Medicine, Research & Experimental 375 4% 0% 273
10 Pathology 291 3% 0% 176

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN DIS MODELING 63196 1% 30% 47
2 SECT OPHTHALMOL NEUROSCI 38052 0% 30% 29
3 MOL MED UNIT 20601 1% 6% 76
4 TRYPANOSOME CELL BIOL UNIT 18247 0% 34% 12
5 CELL BIOL DEV DIS 18120 0% 58% 7
6 DEV BIOL STEM CELL BIOL REGENERAT MED 17756 0% 100% 4
7 GENET MED EA3949 17756 0% 100% 4
8 GENET DEV EVOLUT 17752 0% 67% 6
9 NEUROBIOL ALFRED FESSARD IFR2118 17752 0% 67% 6
10 REFERENCE AFFECT RA GENET OPHTALMOL CARGO 17748 0% 50% 8

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DEVELOPMENT 13049 3% 2% 195
2 AMERICAN JOURNAL OF MEDICAL GENETICS 9030 2% 2% 135
3 VITAMINS AND HORMONES 8018 0% 9% 21
4 DEVELOPMENTAL CELL 6318 1% 2% 61
5 DEVELOPMENTAL BIOLOGY 5173 2% 1% 129
6 JOURNAL OF MEDICAL GENETICS 5020 1% 1% 82
7 HUMAN MOLECULAR GENETICS 4119 1% 1% 97
8 METHODS IN CELL BIOLOGY 3587 1% 2% 45
9 CURRENT BIOLOGY 3556 1% 1% 86
10 AMERICAN JOURNAL OF MEDICAL GENETICS PART A 3440 1% 1% 68

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HEDGEHOG 985813 8% 42% 535 Search HEDGEHOG Search HEDGEHOG
2 GLI 564292 3% 71% 179 Search GLI Search GLI
3 CILIOPATHY 532835 3% 68% 176 Search CILIOPATHY Search CILIOPATHY
4 SMOOTHENED 516443 2% 73% 160 Search SMOOTHENED Search SMOOTHENED
5 HEDGEHOG SIGNALING 515556 3% 62% 187 Search HEDGEHOG+SIGNALING Search HEDGEHOG+SIGNALING
6 SONIC HEDGEHOG 466858 5% 31% 344 Search SONIC+HEDGEHOG Search SONIC+HEDGEHOG
7 JOUBERT SYNDROME 450235 2% 80% 127 Search JOUBERT+SYNDROME Search JOUBERT+SYNDROME
8 PRIMARY CILIA 448707 2% 62% 164 Search PRIMARY+CILIA Search PRIMARY+CILIA
9 BARDET BIEDL SYNDROME 431072 2% 75% 130 Search BARDET+BIEDL+SYNDROME Search BARDET+BIEDL+SYNDROME
10 CYCLOPAMINE 400544 2% 65% 138 Search CYCLOPAMINE Search CYCLOPAMINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BRISCOE, J , THEROND, PP , (2013) THE MECHANISMS OF HEDGEHOG SIGNALLING AND ITS ROLES IN DEVELOPMENT AND DISEASE.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 14. ISSUE 7. P. 416-429 160 77% 320
2 TEGLUND, S , TOFTGARD, R , (2010) HEDGEHOG BEYOND MEDULLOBLASTOMA AND BASAL CELL CARCINOMA.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1805. ISSUE 2. P. 181 -208 280 67% 198
3 ROBBINS, DJ , FEI, DL , RIOBO, NA , (2012) THE HEDGEHOG SIGNAL TRANSDUCTION NETWORK.SCIENCE SIGNALING. VOL. 5. ISSUE 246. P. - 196 87% 98
4 PANDOLFI, S , STECCA, B , (2015) COOPERATIVE INTEGRATION BETWEEN HEDGEHOG-GLI SIGNALLING AND OTHER ONCOGENIC PATHWAYS: IMPLICATIONS FOR CANCER THERAPY.EXPERT REVIEWS IN MOLECULAR MEDICINE. VOL. 17. ISSUE . P. - 232 80% 8
5 YANG, L , XIE, G , FAN, Q , XIE, J , (2010) ACTIVATION OF THE HEDGEHOG-SIGNALING PATHWAY IN HUMAN CANCER AND THE CLINICAL IMPLICATIONS.ONCOGENE. VOL. 29. ISSUE 4. P. 469 -481 169 86% 125
6 WILSON, CW , CHUANG, PT , (2010) MECHANISM AND EVOLUTION OF CYTOSOLIC HEDGEHOG SIGNAL TRANSDUCTION.DEVELOPMENT. VOL. 137. ISSUE 13. P. 2079 -2094 178 88% 77
7 VARJOSALO, M , TAIPALE, J , (2008) HEDGEHOG: FUNCTIONS AND MECHANISMS.GENES & DEVELOPMENT. VOL. 22. ISSUE 18. P. 2454-2472 165 64% 480
8 GOETZ, SC , ANDERSON, KV , (2010) THE PRIMARY CILIUM: A SIGNALLING CENTRE DURING VERTEBRATE DEVELOPMENT.NATURE REVIEWS GENETICS. VOL. 11. ISSUE 5. P. 331 -344 114 73% 612
9 ISHIKAWA, H , MARSHALL, WF , (2011) CILIOGENESIS: BUILDING THE CELL'S ANTENNA.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 12. ISSUE 4. P. 222 -234 119 83% 290
10 MADHIVANAN, K , AGUILAR, RC , (2014) CILIOPATHIES: THE TRAFFICKING CONNECTION.TRAFFIC. VOL. 15. ISSUE 10. P. 1031 -1056 174 82% 15

Classes with closest relation at Level 2


Rank Class id link
1 2024 AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE//POLYCYSTIC KIDNEY DISEASE//ADPKD
2 349 DEVELOPMENTAL BIOLOGY//DEVELOPMENT//NEURAL CREST
3 1653 PRIMARY CILIARY DYSKINESIA//KARTAGENERS SYNDROME//DYNEIN
4 1853 CANCER STEM CELLS//CD133//SIDE POPULATION
5 1425 WNT//BETA CATENIN//FRIZZLED
6 253 DROSOPHILA//DEVELOPMENTAL BIOLOGY//DEVELOPMENT
7 1463 AMELOBLASTOMA//ODONTOGENIC TUMORS//DENTISTRY, ORAL SURGERY & MEDICINE
8 266 RETINITIS PIGMENTOSA//OPHTHALMOLOGY//RETINA
9 2658 ACHONDROPLASIA//SKELETAL DYSPLASIA//HYPOCHONDROPLASIA
10 3382 LISSENCEPHALY//SECKEL SYNDROME//LIS1

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