Class information for:
Level 1: MEDIATOR COMPLEX//CDK8//MED12

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
13537 830 50.3 95%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
71 3       GENETICS & HEREDITY//CHROMATIN//CELL BIOLOGY 83302
2504 2             TFIID//RNA POLYMERASE II//MEDIATOR COMPLEX 3873
13537 1                   MEDIATOR COMPLEX//CDK8//MED12 830

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MEDIATOR COMPLEX authKW 1262045 5% 84% 41
2 CDK8 authKW 640910 3% 62% 28
3 MED12 authKW 436266 3% 46% 26
4 MED19 authKW 342409 1% 85% 11
5 MED13 authKW 331093 1% 100% 9
6 CYCLIN C authKW 257503 2% 50% 14
7 MEDIATOR authKW 229279 9% 8% 75
8 TRAP220 authKW 220729 1% 100% 6
9 MED23 authKW 189194 1% 86% 6
10 MED28 authKW 183941 1% 100% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 5142 40% 0% 336
2 Biochemistry & Molecular Biology 4410 60% 0% 495
3 Genetics & Heredity 1170 17% 0% 138
4 Developmental Biology 1123 8% 0% 64
5 Biophysics 112 5% 0% 44
6 Oncology 96 8% 0% 64
7 Mycology 33 1% 0% 8
8 Plant Sciences 20 4% 0% 32
9 Biology 5 1% 0% 12
10 Chemistry, Medicinal 4 1% 0% 12

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CREAT INITIAT GENOME REGULAT 153282 1% 83% 5
2 DIAGNOST NUCL DEV SDN 54093 1% 29% 5
3 PLANT MEDIATOR 49050 0% 67% 2
4 AOU MED 1 36788 0% 100% 1
5 AZIENDA UNIV POLICLIN AOUSIMT 36788 0% 100% 1
6 AZIENDA UNIV POLICLIN AOUUOC IMMUNOHEMATOL TRANS 36788 0% 100% 1
7 BIOCHEM BIOPHYS 2 36788 0% 100% 1
8 BIOMED INVENTRYBURN MOL CARDIOL 36788 0% 100% 1
9 BREAKTHROUGH BREAST CANC UNITPETERSON C 36788 0% 100% 1
10 CAMPUS LUEBECK BORSTEL 36788 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR CELL 11297 5% 1% 41
2 MOLECULAR AND CELLULAR BIOLOGY 6303 7% 0% 62
3 NATURE STRUCTURAL & MOLECULAR BIOLOGY 2041 1% 1% 11
4 GENES & DEVELOPMENT 1756 2% 0% 19
5 GENES TO CELLS 1542 1% 0% 9
6 JOURNAL OF BIOLOGICAL CHEMISTRY 1538 10% 0% 82
7 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 1324 7% 0% 60
8 GENE EXPRESSION 982 0% 1% 3
9 GENETICS 904 2% 0% 18
10 SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY 894 1% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MEDIATOR COMPLEX 1262045 5% 84% 41 Search MEDIATOR+COMPLEX Search MEDIATOR+COMPLEX
2 CDK8 640910 3% 62% 28 Search CDK8 Search CDK8
3 MED12 436266 3% 46% 26 Search MED12 Search MED12
4 MED19 342409 1% 85% 11 Search MED19 Search MED19
5 MED13 331093 1% 100% 9 Search MED13 Search MED13
6 CYCLIN C 257503 2% 50% 14 Search CYCLIN+C Search CYCLIN+C
7 MEDIATOR 229279 9% 8% 75 Search MEDIATOR Search MEDIATOR
8 TRAP220 220729 1% 100% 6 Search TRAP220 Search TRAP220
9 MED23 189194 1% 86% 6 Search MED23 Search MED23
10 MED28 183941 1% 100% 5 Search MED28 Search MED28

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 POSS, ZC , EBMEIER, CC , TAATJES, DJ , (2013) THE MEDIATOR COMPLEX AND TRANSCRIPTION REGULATION.CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 48. ISSUE 6. P. 575-608 263 60% 83
2 ALLEN, BL , TAATJES, DJ , (2015) THE MEDIATOR COMPLEX: A CENTRAL INTEGRATOR OF TRANSCRIPTION.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 16. ISSUE 3. P. 155 -166 110 57% 69
3 ANSARI, SA , MORSE, RH , (2013) MECHANISMS OF MEDIATOR COMPLEX ACTION IN TRANSCRIPTIONAL ACTIVATION.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 70. ISSUE 15. P. 2743-2756 121 76% 35
4 MALIK, S , ROEDER, RG , (2010) THE METAZOAN MEDIATOR CO-ACTIVATOR COMPLEX AS AN INTEGRATIVE HUB FOR TRANSCRIPTIONAL REGULATION.NATURE REVIEWS GENETICS. VOL. 11. ISSUE 11. P. 761-772 94 76% 275
5 BORGGREFE, T , YUE, XJ , (2011) INTERACTIONS BETWEEN SUBUNITS OF THE MEDIATOR COMPLEX WITH GENE-SPECIFIC TRANSCRIPTION FACTORS.SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. VOL. 22. ISSUE 7. P. 759-768 113 84% 52
6 YIN, JW , WANG, G , (2014) THE MEDIATOR COMPLEX: A MASTER COORDINATOR OF TRANSCRIPTION AND CELL LINEAGE DEVELOPMENT.DEVELOPMENT. VOL. 141. ISSUE 5. P. 977-987 110 72% 32
7 NAPOLI, C , SESSA, M , INFANTE, T , CASAMASSIMI, A , (2012) UNRAVELING FRAMEWORK OF THE ANCESTRAL MEDIATOR COMPLEX IN HUMAN DISEASES.BIOCHIMIE. VOL. 94. ISSUE 3. P. 579-587 103 89% 21
8 CONAWAY, RC , CONAWAY, JW , (2011) ORIGINS AND ACTIVITY OF THE MEDIATOR COMPLEX.SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. VOL. 22. ISSUE 7. P. 729-734 89 80% 48
9 TSAI, KL , TOMOMORI-SATO, C , SATO, S , CONAWAY, RC , CONAWAY, JW , ASTURIAS, FJ , (2014) SUBUNIT ARCHITECTURE AND FUNCTIONAL MODULAR REARRANGEMENTS OF THE TRANSCRIPTIONAL MEDIATOR COMPLEX.CELL. VOL. 157. ISSUE 6. P. 1430 -1444 50 91% 48
10 SAMANTA, S , THAKUR, JK , (2015) IMPORTANCE OF MEDIATOR COMPLEX IN THE REGULATION AND INTEGRATION OF DIVERSE SIGNALING PATHWAYS IN PLANTS.FRONTIERS IN PLANT SCIENCE. VOL. 6. ISSUE . P. - 83 66% 6

Classes with closest relation at Level 1


Rank Class id link
1 2863 TFIID//GENERAL TRANSCRIPTION FACTORS//TFIIA
2 5889 P TEFB//CDK9//RNA POLYMERASE II
3 11310 GAL80//GAL4P//GAL4
4 9000 STEROID HORMONES SECT//AIB1//SRC 3
5 36779 CDK11P58//PITSLRE//CDK11
6 23606 CAK//SPY1//CDK ACTIVATING KINASE
7 8607 HISTONE ACETYLTRANSFERASE//GCN5//MOZ
8 3273 NUCLEOSOME POSITIONING//ISWI//NUCLEOSOME
9 17211 RPB4//RPB7//INTERSPECIFIC COMPLEMENTATION
10 14125 USP22//SET1//UBIQUITIN SPECIFIC PROTEASE 22

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