Class information for:
Level 1: P53//P53 GENE//ONCOGENE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1581 2584 47.0 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
304 3       P53//RETINOBLASTOMA//MDM2 40663
936 2             P53//MDM2//P73 10991
1581 1                   P53//P53 GENE//ONCOGENE 2584

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 P53 authKW 379193 29% 4% 762
2 P53 GENE authKW 73298 2% 11% 57
3 ONCOGENE journal 65366 12% 2% 316
4 P53 PROTEIN authKW 65281 2% 9% 59
5 P53 MUTATION authKW 51209 2% 10% 44
6 P53 TUMOR SUPPRESSOR GENE authKW 33248 1% 14% 20
7 P53 ACCUMULATION authKW 30375 0% 43% 6
8 CIRCULATORY INTERNAL MED address 26583 0% 75% 3
9 WILD TYPE P53 PROTEIN authKW 26583 0% 75% 3
10 MUTANT P53 authKW 24425 1% 10% 21

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 18318 44% 0% 1132
2 Cell Biology 11754 35% 0% 905
3 Biochemistry & Molecular Biology 5479 40% 0% 1026
4 Genetics & Heredity 4439 18% 0% 470
5 Pathology 821 6% 0% 147
6 Hematology 703 6% 0% 150
7 Biology 249 3% 0% 90
8 Virology 245 3% 0% 74
9 Biophysics 134 4% 0% 97
10 Developmental Biology 60 1% 0% 35

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CIRCULATORY INTERNAL MED 26583 0% 75% 3
2 CRC CELL TRANSFORMAT GRP 17720 0% 50% 3
3 NEUROL SURG 8893 15752 0% 67% 2
4 NEW ENGLAND MED MED RADIAT ONCOL 15752 0% 67% 2
5 YCRC GRP P53 15752 0% 67% 2
6 8700 BEVERLY BLVDB121 11815 0% 100% 1
7 A205 11815 0% 100% 1
8 ADULT LEUKAEMIALRF 11815 0% 100% 1
9 ANAL CLIN TOXICOL FARM IMUNOL CLIN 11815 0% 100% 1
10 BABRAHAM BIOINCUBATORS 11815 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOGENE 65366 12% 2% 316
2 CELL GROWTH & DIFFERENTIATION 9648 1% 2% 34
3 INTERNATIONAL JOURNAL OF ONCOLOGY 9064 3% 1% 86
4 MOLECULAR CARCINOGENESIS 6098 1% 1% 38
5 MOLECULAR AND CELLULAR BIOLOGY 4861 4% 0% 97
6 CANCER RESEARCH 2212 3% 0% 88
7 ANTICANCER RESEARCH 2206 2% 0% 61
8 EMBO JOURNAL 1928 2% 0% 54
9 SEMINARS IN CANCER BIOLOGY 1777 1% 1% 13
10 JOURNAL OF CLINICAL PATHOLOGY-CLINICAL MOLECULAR PATHOLOGY EDITION 1435 0% 3% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 P53 379193 29% 4% 762 Search P53 Search P53
2 P53 GENE 73298 2% 11% 57 Search P53+GENE Search P53+GENE
3 P53 PROTEIN 65281 2% 9% 59 Search P53+PROTEIN Search P53+PROTEIN
4 P53 MUTATION 51209 2% 10% 44 Search P53+MUTATION Search P53+MUTATION
5 P53 TUMOR SUPPRESSOR GENE 33248 1% 14% 20 Search P53+TUMOR+SUPPRESSOR+GENE Search P53+TUMOR+SUPPRESSOR+GENE
6 P53 ACCUMULATION 30375 0% 43% 6 Search P53+ACCUMULATION Search P53+ACCUMULATION
7 WILD TYPE P53 PROTEIN 26583 0% 75% 3 Search WILD+TYPE+P53+PROTEIN Search WILD+TYPE+P53+PROTEIN
8 MUTANT P53 24425 1% 10% 21 Search MUTANT+P53 Search MUTANT+P53
9 HUMAN P53 23631 0% 100% 2 Search HUMAN+P53 Search HUMAN+P53
10 MURINE P53 23631 0% 100% 2 Search MURINE+P53 Search MURINE+P53

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KO, LJ , PRIVES, C , (1996) P53: PUZZLE AND PARADIGM.GENES & DEVELOPMENT. VOL. 10. ISSUE 9. P. 1054-1072 138 59% 1985
2 OZBUN, MA , BUTEL, JS , (1995) TUMOR-SUPPRESSOR P53 MUTATIONS AND BREAST-CANCER - A CRITICAL ANALYSIS.ADVANCES IN CANCER RESEARCH, VOL 66. VOL. 66. ISSUE . P. 71-141 267 66% 95
3 GOTTLIEB, TM , OREN, M , (1996) P53 IN GROWTH CONTROL AND NEOPLASIA.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1287. ISSUE 2-3. P. 77-102 198 59% 418
4 DONEHOWER, LA , BRADLEY, A , (1993) THE TUMOR-SUPPRESSOR P53.BIOCHIMICA ET BIOPHYSICA ACTA. VOL. 1155. ISSUE 2. P. 181-205 173 63% 433
5 MAY, P , MAY, E , (1999) TWENTY YEARS OF P53 RESEARCH: STRUCTURAL AND FUNCTIONAL ASPECTS OF THE P53 PROTEIN.ONCOGENE. VOL. 18. ISSUE 53. P. 7621 -7636 145 58% 422
6 HARRIS, CC , (1996) P53 TUMOR SUPPRESSOR GENE: FROM THE BASIC RESEARCH LABORATORY TO THE CLINIC - AN ABRIDGED HISTORICAL PERSPECTIVE.CARCINOGENESIS. VOL. 17. ISSUE 6. P. 1187-1198 166 65% 191
7 PROKOCIMER, M , ROTTER, V , (1994) STRUCTURE AND FUNCTION OF P53 IN NORMAL-CELLS AND THEIR ABERRATIONS IN CANCER-CELLS - PROJECTION ON THE HEMATOLOGIC CELL LINEAGES.BLOOD. VOL. 84. ISSUE 8. P. 2391-2411 158 62% 180
8 MAXWELL, SA , ROTH, JA , (1994) POSTTRANSLATIONAL REGULATION OF P53 TUMOR-SUPPRESSOR PROTEIN FUNCTION.CRITICAL REVIEWS IN ONCOGENESIS. VOL. 5. ISSUE 1. P. 23-57 178 64% 30
9 SELIVANOVA, G , WIMAN, KG , (1995) P53 - A CELL-CYCLE REGULATOR ACTIVATED BY DNA-DAMAGE.ADVANCES IN CANCER RESEARCH, VOL 66. VOL. 66. ISSUE . P. 143-180 140 67% 98
10 LEVINE, AJ , MOMAND, J , FINLAY, CA , (1991) THE P53 TUMOR SUPPRESSOR GENE.NATURE. VOL. 351. ISSUE 6326. P. 453-456 40 77% 3657

Classes with closest relation at Level 1


Rank Class id link
1 8010 MUTANT P53//PRIMA 1//CP 31398
2 29487 PINK EYED UNSTABLE//RADIAT ON AB MOL CELLULAR RADIAT BIOL//3 5 EXONUCLEASE
3 13947 P53//AREA BIOPATOL//BCL 2
4 19114 LI FRAUMENI SYNDROME//LI FRAUMENI//GERMLINE TP53 MUTATION
5 16830 RAD P53//RECOMBINANT ADENOVIRUS P53//ADENOVIRAL MEDIATED INTERFERON ALPHA
6 27700 JOINT SERV BIOMARKER EVALUAT ONCOL//KI67 SCORE//LOCDIR
7 9064 P21//P21WAF1 CIP1//P21WAF1
8 1860 MDM2//MDMX//MDM4
9 11121 TUMOR FRONT GRADING//ORAL SQUAMOUS CELL CARCINOMA//P53
10 32875 GEL FIBERGLASS//TERATOL EXPT ONCOL//KORET VET MED

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