Class information for:
Level 1: GRP78//GLUCOSE REGULATED PROTEIN 78//CELL SURFACE GRP78

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
16599 645 40.7 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
204 3       PROTEASOME//UBIQUITIN//UNFOLDED PROTEIN RESPONSE 52492
1548 2             UNFOLDED PROTEIN RESPONSE//ENDOPLASMIC RETICULUM STRESS//ER STRESS 7418
16599 1                   GRP78//GLUCOSE REGULATED PROTEIN 78//CELL SURFACE GRP78 645

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GRP78 authKW 2203783 22% 33% 140
2 GLUCOSE REGULATED PROTEIN 78 authKW 594799 5% 37% 34
3 CELL SURFACE GRP78 authKW 197250 1% 83% 5
4 USC NORRIS COMPREHENS CANC address 180483 5% 13% 30
5 LI KA SHING MED SCI address 154927 1% 55% 6
6 GRP94 authKW 137789 3% 15% 19
7 GRP78 BIP authKW 112768 1% 26% 9
8 ANTIBODY DIRECTED AGAINST THE COOH TERMINAL DOMAIN OF GRP78 authKW 94681 0% 100% 2
9 BIOL AMBIENTAL SCI TECHNOL address 94681 0% 100% 2
10 GLUCOSE REGULATED PROTEIN OF 78 KDA authKW 94681 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 3145 37% 0% 237
2 Cell Biology 1543 26% 0% 168
3 Biochemistry & Molecular Biology 697 30% 0% 193
4 Pathology 52 3% 0% 21
5 Physiology 44 4% 0% 25
6 Medicine, Research & Experimental 37 4% 0% 26
7 Genetics & Heredity 30 4% 0% 28
8 Chemistry, Medicinal 14 2% 0% 14
9 Pharmacology & Pharmacy 13 5% 0% 35
10 Biochemical Research Methods 10 2% 0% 15

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 USC NORRIS COMPREHENS CANC 180483 5% 13% 30
2 LI KA SHING MED SCI 154927 1% 55% 6
3 BIOL AMBIENTAL SCI TECHNOL 94681 0% 100% 2
4 48R 47340 0% 100% 1
5 BRICKOTO KU 47340 0% 100% 1
6 BSP GDD GTR TD TR2W 47340 0% 100% 1
7 C CECCARELLI NEUROBIOL 47340 0% 100% 1
8 CELL BIOL AND GENET 47340 0% 100% 1
9 CELLULAR VASC IMMUNOL 47340 0% 100% 1
10 CELLULAR VASCULAR IMMUNOL 47340 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CELLULAR PHYSIOLOGY 1500 3% 0% 18
2 CANCER RESEARCH 1051 5% 0% 30
3 MOLECULAR AND CELLULAR BIOLOGY 661 3% 0% 18
4 CELL STRESS & CHAPERONES 661 1% 0% 4
5 TUMOR BIOLOGY 609 1% 0% 9
6 ONCOTARGET 536 2% 0% 12
7 JOURNAL OF CELLULAR BIOCHEMISTRY 515 2% 0% 10
8 JOURNAL OF BIOLOGICAL CHEMISTRY 492 7% 0% 42
9 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 435 0% 0% 2
10 MELANOMA RESEARCH 424 1% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GRP78 2203783 22% 33% 140 Search GRP78 Search GRP78
2 GLUCOSE REGULATED PROTEIN 78 594799 5% 37% 34 Search GLUCOSE+REGULATED+PROTEIN+78 Search GLUCOSE+REGULATED+PROTEIN+78
3 CELL SURFACE GRP78 197250 1% 83% 5 Search CELL+SURFACE+GRP78 Search CELL+SURFACE+GRP78
4 GRP94 137789 3% 15% 19 Search GRP94 Search GRP94
5 GRP78 BIP 112768 1% 26% 9 Search GRP78+BIP Search GRP78+BIP
6 ANTIBODY DIRECTED AGAINST THE COOH TERMINAL DOMAIN OF GRP78 94681 0% 100% 2 Search ANTIBODY+DIRECTED+AGAINST+THE+COOH+TERMINAL+DOMAIN+OF+GRP78 Search ANTIBODY+DIRECTED+AGAINST+THE+COOH+TERMINAL+DOMAIN+OF+GRP78
7 GLUCOSE REGULATED PROTEIN OF 78 KDA 94681 0% 100% 2 Search GLUCOSE+REGULATED+PROTEIN+OF+78+KDA Search GLUCOSE+REGULATED+PROTEIN+OF+78+KDA
8 GLUCOSE REGULATED STRESS 94681 0% 100% 2 Search GLUCOSE+REGULATED+STRESS Search GLUCOSE+REGULATED+STRESS
9 GRP78 PROTEIN 94681 0% 100% 2 Search GRP78+PROTEIN Search GRP78+PROTEIN
10 HSPA5 GRP78 BIP 94681 0% 100% 2 Search HSPA5+GRP78+BIP Search HSPA5+GRP78+BIP

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 LEE, AS , (2014) GLUCOSE-REGULATED PROTEINS IN CANCER: MOLECULAR MECHANISMS AND THERAPEUTIC POTENTIAL.NATURE REVIEWS CANCER. VOL. 14. ISSUE 4. P. 263 -276 96 51% 79
2 LI, ZW , LI, ZY , (2012) GLUCOSE REGULATED PROTEIN 78: A CRITICAL LINK BETWEEN TUMOR MICROENVIRONMENT AND CANCER HALLMARKS.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1826. ISSUE 1. P. 13 -22 70 48% 34
3 ZHANG, Y , LEE, AS , NI, M , (2011) BEYOND THE ENDOPLASMIC RETICULUM: ATYPICAL GRP78 IN CELL VIABILITY, SIGNALLING AND THERAPEUTIC TARGETING.BIOCHEMICAL JOURNAL. VOL. 434. ISSUE . P. 181 -188 39 58% 140
4 ZHANG, Y , TSENG, CC , TSAI, YL , FU, XY , SCHIFF, R , LEE, AS , (2013) CANCER CELLS RESISTANT TO THERAPY PROMOTE CELL SURFACE RELOCALIZATION OF GRP78 WHICH COMPLEXES WITH PI3K AND ENHANCES PI(3,4,5)P3 PRODUCTION.PLOS ONE. VOL. 8. ISSUE 11. P. - 36 75% 25
5 HARDY, B , RAITER, A , YAKIMOV, M , VILKIN, A , NIV, Y , (2012) COLON CANCER CELLS EXPRESSING CELL SURFACE GRP78 AS A MARKER FOR REDUCED TUMORIGENICITY.CELLULAR ONCOLOGY. VOL. 35. ISSUE 5. P. 345 -354 33 85% 11
6 ZHANG, Y , LIU, R , NI, M , GILL, P , LEE, AS , (2010) CELL SURFACE RELOCALIZATION OF THE ENDOPLASMIC RETICULUM CHAPERONE AND UNFOLDED PROTEIN RESPONSE REGULATOR GRP78/BIP.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 285. ISSUE 20. P. 15065 -15075 31 76% 91
7 LI, JZ , LEE, AS , (2006) STRESS INDUCTION OF GRP78/BIP AND ITS ROLE IN CANCER.CURRENT MOLECULAR MEDICINE. VOL. 6. ISSUE 1. P. 45-54 48 40% 354
8 LEE, AS , BRANDHORST, S , RANGEL, DF , NAVARRETE, G , COHEN, P , LONGO, VD , CHEN, J , GROSHEN, S , MORGAN, TE , DUBEAU, L , (2017) EFFECTS OF PROLONGED GRP78 HAPLOINSUFFICIENCY ON ORGAN HOMEOSTASIS, BEHAVIOR, CANCER AND CHEMOTOXIC RESISTANCE IN AGED MICE.SCIENTIFIC REPORTS. VOL. 7. ISSUE . P. - 33 67% 0
9 ZHANG, YK , LI, NH , WANG, DL , CHEN, YQ , LI, G , (2015) EXPRESSION AND SIGNIFICANCE OF GLUCOSE-REGULATED PROTEIN 78 IN HUMAN OSTEOSARCOMA.ONCOLOGY LETTERS. VOL. 9. ISSUE 5. P. 2268 -2274 26 87% 0
10 LEE, AS , (2007) GRP78 INDUCTION IN CANCER: THERAPEUTIC AND PROGNOSTIC IMPLICATIONS.CANCER RESEARCH. VOL. 67. ISSUE 8. P. 3496-3499 22 73% 394

Classes with closest relation at Level 1


Rank Class id link
1 415 UNFOLDED PROTEIN RESPONSE//ENDOPLASMIC RETICULUM STRESS//ER STRESS
2 35375 ORP150//OXYGEN REGULATED PROTEIN 150//150 KD OXYGEN REGULATED PROTEIN
3 8051 IMMUNOTHER Y CANC INFECT DIS//GP96//HEAT SHOCK PROTEIN
4 30421 NELFINAVIR//SAQUINAVIR NO//BECN1 PTDINS3K COMPLEX
5 6152 DNAJ//DNAK//GRPE
6 28292 RETICULOCALBIN//CALUMENIN//BIOCHEM BIOMOL RECOGNIT
7 22222 CRIPTO 1//CRIPTO//TUMOR GROWTH TOR SECT
8 3658 THERMOTOLERANCE//HEAT SHOCK//TSAF8
9 12856 CALRETICULIN//CALNEXIN//CALNEXIN HOMOLOGUE
10 13046 PHAGE DISPLAY//IN VIVO PHAGE DISPLAY//NGR HTNF

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