Class information for:
Level 1: TAK1//TAB1//TGF BETA ACTIVATED KINASE 1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
24258 318 42.3 96%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
204 3       PROTEASOME//UBIQUITIN//UNFOLDED PROTEIN RESPONSE 52492
1195 2             JNK//ERK5//MAP KINASE 9252
24258 1                   TAK1//TAB1//TGF BETA ACTIVATED KINASE 1 318

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TAK1 authKW 2579087 23% 37% 72
2 TAB1 authKW 553078 4% 48% 12
3 TGF BETA ACTIVATED KINASE 1 authKW 427732 2% 64% 7
4 LYTAK1 authKW 288068 1% 100% 3
5 TAB3 authKW 256058 1% 67% 4
6 TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1 authKW 246908 2% 43% 6
7 5Z 7 OXOZEAENOL authKW 240052 2% 50% 5
8 TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1 TAK1 authKW 216049 1% 75% 3
9 7 AMINO FURO2 3 CPYRIDINE authKW 192045 1% 100% 2
10 LYSINE 158 authKW 192045 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 1147 31% 0% 100
2 Biochemistry & Molecular Biology 1062 48% 0% 154
3 Oncology 191 14% 0% 46
4 Immunology 112 11% 0% 34
5 Biophysics 75 7% 0% 21
6 Medicine, Research & Experimental 34 5% 0% 16
7 Genetics & Heredity 33 6% 0% 18
8 Hematology 30 4% 0% 12
9 Developmental Biology 18 2% 0% 6
10 Chemistry, Medicinal 15 3% 0% 9

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PATHOGEN BIOCHEM 153346 6% 8% 19
2 BIOPHYS BIOCHEM S625A 96023 0% 100% 1
3 CARDIOMETAB NUTRINSERMICANUMR S1166 96023 0% 100% 1
4 CELL ENGN BIOL ENGN 96023 0% 100% 1
5 DIC PATHOGEN BIOCHEM 96023 0% 100% 1
6 EXPT THER EUTUNIT 143 96023 0% 100% 1
7 HEPATOBILICNY PANCREAT SURG 96023 0% 100% 1
8 HOST DEF EXPLORATORY ADV TECHNOL ERATO 96023 0% 100% 1
9 ICRM CHEM MOL RECOGNIT 96023 0% 100% 1
10 IMAGING PLATFORM SPATIOTEMPORAL REGULAT 96023 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELLULAR SIGNALLING 1400 3% 0% 8
2 JOURNAL OF BIOLOGICAL CHEMISTRY 1135 14% 0% 43
3 FEBS OPEN BIO 812 1% 0% 2
4 SCIENCE SIGNALING 554 1% 0% 3
5 SEIKAGAKU 492 1% 0% 3
6 CELL DEATH AND DIFFERENTIATION 479 1% 0% 4
7 MOLECULAR CANCER RESEARCH 458 1% 0% 3
8 NATURE IMMUNOLOGY 386 1% 0% 3
9 CELL DEATH & DISEASE 361 1% 0% 3
10 BIOCHEMISTRY AND CELL BIOLOGY 333 0% 0% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TAK1 2579087 23% 37% 72 Search TAK1 Search TAK1
2 TAB1 553078 4% 48% 12 Search TAB1 Search TAB1
3 TGF BETA ACTIVATED KINASE 1 427732 2% 64% 7 Search TGF+BETA+ACTIVATED+KINASE+1 Search TGF+BETA+ACTIVATED+KINASE+1
4 LYTAK1 288068 1% 100% 3 Search LYTAK1 Search LYTAK1
5 TAB3 256058 1% 67% 4 Search TAB3 Search TAB3
6 TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1 246908 2% 43% 6 Search TRANSFORMING+GROWTH+FACTOR+BETA+ACTIVATED+KINASE+1 Search TRANSFORMING+GROWTH+FACTOR+BETA+ACTIVATED+KINASE+1
7 5Z 7 OXOZEAENOL 240052 2% 50% 5 Search 5Z+7+OXOZEAENOL Search 5Z+7+OXOZEAENOL
8 TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1 TAK1 216049 1% 75% 3 Search TRANSFORMING+GROWTH+FACTOR+BETA+ACTIVATED+KINASE+1+TAK1 Search TRANSFORMING+GROWTH+FACTOR+BETA+ACTIVATED+KINASE+1+TAK1
9 7 AMINO FURO2 3 CPYRIDINE 192045 1% 100% 2 Search 7+AMINO+FURO2+3+CPYRIDINE Search 7+AMINO+FURO2+3+CPYRIDINE
10 LYSINE 158 192045 1% 100% 2 Search LYSINE+158 Search LYSINE+158

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 SAKURAI, H , (2012) TARGETING OF TAK1 IN INFLAMMATORY DISORDERS AND CANCER.TRENDS IN PHARMACOLOGICAL SCIENCES. VOL. 33. ISSUE 10. P. 522 -530 52 58% 107
2 ROH, YS , SONG, J , SEKI, E , (2014) TAK1 REGULATES HEPATIC CELL SURVIVAL AND CARCINOGENESIS.JOURNAL OF GASTROENTEROLOGY. VOL. 49. ISSUE 2. P. 185-194 52 70% 12
3 AJIBADE, AA , WANG, HY , WANG, RF , (2013) CELL TYPE-SPECIFIC FUNCTION OF TAK1 IN INNATE IMMUNE SIGNALING.TRENDS IN IMMUNOLOGY. VOL. 34. ISSUE 7. P. 307-316 57 56% 53
4 MIHALY, SR , MORIOKA, S , NINOMIYA-TSUJI, J , TAKAESU, G , (2014) ACTIVATED MACROPHAGE SURVIVAL IS COORDINATED BY TAK1 BINDING PROTEINS.PLOS ONE. VOL. 9. ISSUE 4. P. - 34 65% 3
5 DAI, L , THU, CA , LIU, XY , XI, JJ , CHEUNG, PCF , (2012) TAK1, MORE THAN JUST INNATE IMMUNITY.IUBMB LIFE. VOL. 64. ISSUE 10. P. 825-834 36 52% 37
6 MIHALY, SR , NINOMIYA-TSUJI, J , MORIOKA, S , (2014) TAK1 CONTROL OF CELL DEATH.CELL DEATH AND DIFFERENTIATION. VOL. 21. ISSUE 11. P. 1667 -1676 45 35% 25
7 HOU, MF , HUNG, WC , CHIANG, CH , HUANG, HL , (2015) TARGETING OF TGF-BETA-ACTIVATED PROTEIN KINASE 1 INHIBITS CHEMOKINE (C-C MOTIF) RECEPTOR 7 EXPRESSION, TUMOR GROWTH AND METASTASIS IN BREAST CANCER.ONCOTARGET. VOL. 6. ISSUE 2. P. 995 -1007 23 62% 6
8 CHEN, IT , HSU, PH , HSU, WC , CHEN, NJ , TSENG, PH , (2015) POLYUBIQUITINATION OF TRANSFORMING GROWTH FACTOR BETA-ACTIVATED KINASE 1 (TAK1) AT LYSINE 562 RESIDUE REGULATES TLR4-MEDIATED JNK AND P38 MAPK ACTIVATION.SCIENTIFIC REPORTS. VOL. 5. ISSUE . P. - 25 56% 6
9 WANG, JS , WU, D , HUANG, DY , LIN, WW , (2015) TAK1 INHIBITION-INDUCED RIP1-DEPENDENT APOPTOSIS IN MURINE MACROPHAGES RELIES ON CONSTITUTIVE TNF-ALPHA SIGNALING AND ROS PRODUCTION.JOURNAL OF BIOMEDICAL SCIENCE. VOL. 22. ISSUE . P. - 27 48% 4
10 INAGAKI, M , OMORI, E , KIM, JY , KOMATSU, Y , SCOTT, G , RAY, MK , YAMADA, G , MATSUMOTO, K , MISHINA, Y , NINOMIYA-TSUJI, J , (2008) TAK1-BINDING PROTEIN 1, TAB1, MEDIATES OSMOTIC STRESS-INDUCED TAK1 ACTIVATION BUT IS DISPENSABLE FOR TAK1-MEDIATED CYTOKINE SIGNALING.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 283. ISSUE 48. P. 33080-33086 24 62% 29

Classes with closest relation at Level 1


Rank Class id link
1 13288 IRAK 4//TIR DOMAIN//IRAK
2 17952 TRAF4//TRAF6//TRAF2
3 21849 RESORCYLIC ACID LACTONES//LASIODIPLODIN//HYPOTHEMYCIN
4 31504 NEMO LIKE KINASE//NLK//UNIT NERVOUS DEV SYST
5 10004 NECROPTOSIS//RIP3//RIP1
6 15482 BCL10//PKC THETA//CARMA3
7 500 NF KAPPA B//IKK//I KAPPA B
8 22795 ASK1//PP5//PROTEIN PHOSPHATASE 5
9 3837 DEUBIQUITINATING ENZYME//UBIQUITIN//DEUBIQUITINASE
10 29236 TPL2//TPL 2//COT TPL2

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