Class information for:
Level 1: FRATAXIN//FRIEDREICHS ATAXIA//FRIEDREICH ATAXIA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3134 2056 45.5 84%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
603 3       HUNTINGTONS DISEASE//SPINOCEREBELLAR ATAXIA//POLYGLUTAMINE 14359
1711 2             SPINOCEREBELLAR ATAXIA//HEREDITARY SPASTIC PARAPLEGIA//FRIEDREICHS ATAXIA 6674
3134 1                   FRATAXIN//FRIEDREICHS ATAXIA//FRIEDREICH ATAXIA 2056

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FRATAXIN authKW 2200185 8% 86% 173
2 FRIEDREICHS ATAXIA authKW 2191144 11% 67% 220
3 FRIEDREICH ATAXIA authKW 2145748 9% 77% 187
4 ZYTOBIOL ZYTOPATHOL address 558105 3% 62% 61
5 ISCU authKW 404996 1% 91% 30
6 CYSTEINE DESULFURASE authKW 361206 1% 81% 30
7 IRON SULFUR CLUSTER authKW 230849 5% 17% 93
8 ZYTOBIOL address 226497 1% 51% 30
9 BRUCE LEFROY GENET HLTH address 198910 2% 31% 43
10 ISCA authKW 194039 1% 93% 14

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 5459 44% 0% 900
2 Clinical Neurology 4403 21% 0% 434
3 Genetics & Heredity 2086 14% 0% 295
4 Neurosciences 556 12% 0% 246
5 Cell Biology 452 10% 0% 196
6 Biophysics 264 5% 0% 107
7 Microbiology 104 4% 0% 92
8 Pediatrics 66 3% 0% 62
9 Medicine, Research & Experimental 63 3% 0% 68
10 Cardiac & Cardiovascular System 33 3% 0% 61

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ZYTOBIOL ZYTOPATHOL 558105 3% 62% 61
2 ZYTOBIOL 226497 1% 51% 30
3 BRUCE LEFROY GENET HLTH 198910 2% 31% 43
4 EVANS CHEM 116692 1% 30% 26
5 MITOCHONDRIA MET OXIDAT ST S 95037 0% 80% 8
6 REFERENCE UNIT HEREDITARY ATAXIAS PAR LEGIAS 59400 0% 100% 4
7 CHAIRE GENET HUMAINE 59376 1% 25% 16
8 BRUCE LEFROY 45247 0% 38% 8
9 GRP BIOQUIM EST OXIDATIU 44550 0% 100% 3
10 U596 40845 1% 16% 17

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CEREBELLUM 11923 1% 3% 27
2 HUMAN MOLECULAR GENETICS 9892 4% 1% 81
3 CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES 4186 1% 1% 29
4 MITOCHONDRION 3548 1% 2% 16
5 NEUROGENETICS 2439 0% 2% 10
6 MOVEMENT DISORDERS 2427 2% 1% 33
7 JOURNAL OF BIOLOGICAL CHEMISTRY 2209 8% 0% 157
8 JOURNAL OF NEUROLOGY 2152 1% 0% 30
9 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 1861 1% 1% 16
10 BIOCHEMISTRY 1493 4% 0% 76

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FRATAXIN 2200185 8% 86% 173 Search FRATAXIN Search FRATAXIN
2 FRIEDREICHS ATAXIA 2191144 11% 67% 220 Search FRIEDREICHS+ATAXIA Search FRIEDREICHS+ATAXIA
3 FRIEDREICH ATAXIA 2145748 9% 77% 187 Search FRIEDREICH+ATAXIA Search FRIEDREICH+ATAXIA
4 ISCU 404996 1% 91% 30 Search ISCU Search ISCU
5 CYSTEINE DESULFURASE 361206 1% 81% 30 Search CYSTEINE+DESULFURASE Search CYSTEINE+DESULFURASE
6 IRON SULFUR CLUSTER 230849 5% 17% 93 Search IRON+SULFUR+CLUSTER Search IRON+SULFUR+CLUSTER
7 ISCA 194039 1% 93% 14 Search ISCA Search ISCA
8 FRDA 191447 1% 68% 19 Search FRDA Search FRDA
9 ISCS 165278 1% 70% 16 Search ISCS Search ISCS
10 FE S CLUSTER 155368 1% 35% 30 Search FE+S+CLUSTER Search FE+S+CLUSTER

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 SANTOS, R , LEFEVRE, S , SLIWA, D , SEGUIN, A , CAMADRO, JM , LESUISSE, E , (2010) FRIEDREICH ATAXIA: MOLECULAR MECHANISMS, REDOX CONSIDERATIONS, AND THERAPEUTIC OPPORTUNITIES.ANTIOXIDANTS & REDOX SIGNALING. VOL. 13. ISSUE 5. P. 651 -690 264 87% 59
2 MAIO, N , ROUAULT, TA , (2015) IRON-SULFUR CLUSTER BIOGENESIS IN MAMMALIAN CELLS: NEW INSIGHTS INTO THE MOLECULAR MECHANISMS OF CLUSTER DELIVERY.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. VOL. 1853. ISSUE 6. P. 1493 -1512 191 61% 29
3 XU, XM , MOLLER, SG , (2011) IRON-SULFUR CLUSTERS: BIOGENESIS, MOLECULAR MECHANISMS, AND THEIR FUNCTIONAL SIGNIFICANCE.ANTIOXIDANTS & REDOX SIGNALING. VOL. 15. ISSUE 1. P. 271 -307 220 66% 40
4 MARMOLINO, D , (2011) FRIEDREICH'S ATAXIA: PAST, PRESENT AND FUTURE.BRAIN RESEARCH REVIEWS. VOL. 67. ISSUE 1-2. P. 311 -330 157 91% 47
5 ROCHE, B , AUSSEL, L , EZRATY, B , MANDIN, P , PY, B , BARRAS, F , (2013) IRON/SULFUR PROTEINS BIOGENESIS IN PROKARYOTES: FORMATION, REGULATION AND DIVERSITY.BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. VOL. 1827. ISSUE 3. P. 455-469 144 73% 79
6 LILL, R , HOFFMANN, B , MOLIK, S , PIERIK, AJ , RIETZSCHEL, N , STEHLING, O , UZARSKA, MA , WEBERT, H , WILBRECHT, C , MUHLENHOFF, U , (2012) THE ROLE OF MITOCHONDRIA IN CELLULAR IRON-SULFUR PROTEIN BIOGENESIS AND IRON METABOLISM.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. VOL. 1823. ISSUE 9. P. 1491 -1508 144 61% 164
7 VAUBEL, RA , ISAYA, G , (2013) IRON-SULFUR CLUSTER SYNTHESIS, IRON HOMEOSTASIS AND OXIDATIVE STRESS IN FRIEDREICH ATAXIA.MOLECULAR AND CELLULAR NEUROSCIENCE. VOL. 55. ISSUE . P. 50 -61 124 89% 31
8 PUCCIO, H , ANHEIM, M , TRANCHANT, C , (2014) PATHOPHYSIOGICAL AND THERAPEUTIC PROGRESS IN FRIEDREICH ATAXIA.REVUE NEUROLOGIQUE. VOL. 170. ISSUE 5. P. 355-365 122 95% 8
9 MARTELLI, A , PUCCIO, H , (2014) DYSREGULATION OF CELLULAR IRON METABOLISM IN FRIEDREICH ATAXIA: FROM PRIMARY IRON-SULFUR CLUSTER DEFICIT TO MITOCHONDRIAL IRON ACCUMULATION.FRONTIERS IN PHARMACOLOGY. VOL. 5. ISSUE . P. - 109 87% 24
10 BLANC, B , GEREZ, C , DE CHOUDENS, SA , (2015) ASSEMBLY OF FE/S PROTEINS IN BACTERIAL SYSTEMS BIOCHEMISTRY OF THE BACTERIAL ISC SYSTEM.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. VOL. 1853. ISSUE 6. P. 1436 -1447 98 90% 10

Classes with closest relation at Level 1


Rank Class id link
1 26667 TANDOSPIRONE CITRATE//CORTICAL CEREBELLAR ATROPHY//NEUROBEHAV NEUROBIOL NEUROPSYCHOL UNIT
2 15827 AFT1//FET3//SIDEROPHORE
3 16834 SECT GENE STRUCT DIS//REPEAT INSTABILITY//MUTS BETA
4 22273 ARSACS//AOA2//SENATAXIN
5 2557 SPINOCEREBELLAR ATAXIA//MACHADO JOSEPH DISEASE//SCA2
6 9458 IRON REGULATORY PROTEIN//IRON RESPONSIVE ELEMENT//IRON REGULATORY PROTEIN 1
7 14459 BIOTIN SYNTHASE//BIOTIN BIOSYNTHESIS//RADICAL SAM
8 16240 X LINKED SIDEROBLASTIC ANEMIA//ALAS2//5 AMINOLEVULINATE SYNTHASE
9 21708 IDEBENONE//SOLANESOL//2 3 4 5 TETRAMETHOXYTOLUENE
10 16799 BROWN BOWEL SYNDROME//VITAMIN E DEFICIENCY//ALPHA TOCOPHEROL TRANSFER PROTEIN GENE

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