Class information for:
Level 2: HEAT SHOCK PROTEIN//HSP90//HSP70

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
290 18900 43.8 84%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
410 3       HEAT SHOCK PROTEIN//HSP90//HSP70 29410
290 2             HEAT SHOCK PROTEIN//HSP90//HSP70 18900
1212 1                   HSP90//GELDANAMYCIN//HSP90 INHIBITORS 2782
3658 1                   THERMOTOLERANCE//HEAT SHOCK//TSAF8 1936
4088 1                   CHAPERONIN//GROEL//GROES 1849
5052 1                   THERMOTOLERANCE//HEAT SHOCK TRANSCRIPTION FACTOR//HEAT STRESS 1682
5282 1                   HSP27//HEAT SHOCK PROTEIN 27//HEAT SHOCK PROTEIN 1646
6152 1                   DNAJ//DNAK//GRPE 1521
8051 1                   IMMUNOTHER Y CANC INFECT DIS//GP96//HEAT SHOCK PROTEIN 1299
9163 1                   HEAT SHOCK PROTEIN//HSP60//HEAT SHOCK PROTEIN 60 1182
9499 1                   HEAT SHOCK PROTEIN//HSP72//PHARMACOL CARDIOVASC EXPT BIOMOL 1150
9533 1                   HSF1//HEAT SHOCK FACTOR//HEAT SHOCK FACTOR 1 1147
14348 1                   HSP70//EMBRYOTOXICOL SECT//HEAT SHOCK PROTEIN 775
17983 1                   BAG 1//BAG3//DR H BLISS MURPHY CANC 572
23265 1                   CRIT CARE MED OSB5//I KAPPA KINASE//QINGHUOBAIDUYIN 352
24320 1                   HSPA2//HSP70 2//HEAT SHOCK PROTEIN A2 316
25216 1                   GERANYLGERANYLACETONE//TEPRENONE//GASTRIC MUCOSAL CELLS 287
29315 1                   MORTALIN//GRP75//UBXN2A 188
32871 1                   HSP105//HARD TISSUE PATHOL UNIT//HSP105 ALPHA 133
36244 1                   ANTIBODIES CULTURE HEAT SHOCK PROTEIN//CDNA INSERTS//HSP 70 KDA HEAT SHOCK PROTEIN FAMILY 83

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 HEAT SHOCK PROTEIN authKW 1349458 12% 38% 2212
2 HSP90 authKW 618422 4% 51% 750
3 HSP70 authKW 601470 5% 37% 1010
4 CHAPERONIN authKW 467298 2% 74% 390
5 CELL STRESS & CHAPERONES journal 398347 3% 47% 529
6 MOLECULAR CHAPERONE authKW 381288 3% 39% 612
7 GROEL authKW 221683 1% 53% 258
8 HEAT SHOCK authKW 219482 3% 24% 572
9 GELDANAMYCIN authKW 213030 1% 60% 222
10 HSP27 authKW 203213 1% 46% 276

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 32402 36% 0% 6853
2 Cell Biology 31132 22% 1% 4160
3 Oncology 5649 11% 0% 2063
4 Biophysics 4655 7% 0% 1272
5 Plant Sciences 2505 7% 0% 1254
6 Immunology 2383 7% 0% 1367
7 Physiology 1428 4% 0% 760
8 Genetics & Heredity 1243 5% 0% 916
9 Biology 871 3% 0% 500
10 Medicine, Research & Experimental 647 3% 0% 646

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IMMUNOTHER Y CANC INFECT DIS 65080 0% 55% 73
2 RICE BIOMED 20926 0% 33% 39
3 EMBRYOTOXICOL SECT 18564 0% 48% 24
4 BOYER 18146 0% 75% 15
5 PROGRAM MOL PHARMACOL CHEM 17626 0% 27% 40
6 CANC UK CANC THER EUT 16584 0% 22% 47
7 SECT STRUCT BIOL 15491 0% 21% 47
8 SIGNAL TRANSDUCT MOL PHARMACOL TEAM 13626 0% 65% 13
9 BIOMED BIOTECHNOL UNIT 12732 0% 44% 18
10 MOL ST S PONSE 12152 0% 54% 14

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 CELL STRESS & CHAPERONES 398347 3% 47% 529
2 INTERNATIONAL JOURNAL OF HYPERTHERMIA 17985 1% 8% 148
3 JOURNAL OF BIOLOGICAL CHEMISTRY 9571 5% 1% 1019
4 MOLECULAR AND CELLULAR BIOLOGY 5731 2% 1% 293
5 JOURNAL OF MOLECULAR BIOLOGY 4131 1% 1% 257
6 JOURNAL OF CELLULAR PHYSIOLOGY 3346 1% 2% 150
7 EXPERIMENTAL CELL RESEARCH 3003 1% 1% 161
8 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2858 2% 1% 382
9 DEVELOPMENTAL GENETICS 2344 0% 4% 37
10 EMBO JOURNAL 2307 1% 1% 166

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 HEAT SHOCK PROTEIN 1349458 12% 38% 2212 Search HEAT+SHOCK+PROTEIN Search HEAT+SHOCK+PROTEIN
2 HSP90 618422 4% 51% 750 Search HSP90 Search HSP90
3 HSP70 601470 5% 37% 1010 Search HSP70 Search HSP70
4 CHAPERONIN 467298 2% 74% 390 Search CHAPERONIN Search CHAPERONIN
5 MOLECULAR CHAPERONE 381288 3% 39% 612 Search MOLECULAR+CHAPERONE Search MOLECULAR+CHAPERONE
6 GROEL 221683 1% 53% 258 Search GROEL Search GROEL
7 HEAT SHOCK 219482 3% 24% 572 Search HEAT+SHOCK Search HEAT+SHOCK
8 GELDANAMYCIN 213030 1% 60% 222 Search GELDANAMYCIN Search GELDANAMYCIN
9 HSP27 203213 1% 46% 276 Search HSP27 Search HSP27
10 HEAT SHOCK PROTEIN 70 189078 2% 36% 326 Search HEAT+SHOCK+PROTEIN+70 Search HEAT+SHOCK+PROTEIN+70

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 WEGELE, H , MULLER, L , BUCHNER, J , (2004) HSP70 AND HSP90 - A RELAY TEAM FOR PROTEIN FOLDING.REVIEWS OF PHYSIOLOGY, BIOCHEMISTRY AND PHARMACOLOGY. VOL. 151. ISSUE . P. 1-44 272 69% 339
2 RADONS, J , (2016) THE HUMAN HSP70 FAMILY OF CHAPERONES: WHERE DO WE STAND?.CELL STRESS & CHAPERONES. VOL. 21. ISSUE 3. P. 379 -404 194 66% 9
3 SNOECKX, LHEH , CORNELUSSEN, RN , VAN NIEUWENHOVEN, FA , RENEMAN, RS , VAN DER VUSSE, GJ , (2001) HEAT SHOCK PROTEINS AND CARDIOVASCULAR PATHOPHYSIOLOGY.PHYSIOLOGICAL REVIEWS. VOL. 81. ISSUE 4. P. 1461 -1497 304 73% 235
4 WHITESELL, L , LINDQUIST, SL , (2005) HSP90 AND THE CHAPERONING OF CANCER.NATURE REVIEWS CANCER. VOL. 5. ISSUE 10. P. 761-772 116 85% 1223
5 CIOCCA, DR , CALDERWOOD, SK , (2005) HEAT SHOCK PROTEINS IN CANCER: DIAGNOSTIC, PROGNOSTIC, PREDICTIVE, AND TREATMENT IMPLICATIONS.CELL STRESS & CHAPERONES. VOL. 10. ISSUE 2. P. 86-103 159 78% 637
6 CIOCCA, DR , ARRIGO, AP , CALDERWOOD, SK , (2013) HEAT SHOCK PROTEINS AND HEAT SHOCK FACTOR 1 IN CARCINOGENESIS AND TUMOR DEVELOPMENT: AN UPDATE.ARCHIVES OF TOXICOLOGY. VOL. 87. ISSUE 1. P. 19-48 204 62% 78
7 JACKSON, SE , (2013) HSP90: STRUCTURE AND FUNCTION.MOLECULAR CHAPERONES. VOL. 328. ISSUE . P. 155-240 226 60% 53
8 KHANDELWAL, A , CROWLEY, VM , BLAGG, BSJ , (2016) NATURAL PRODUCT INSPIRED N-TERMINAL HSP90 INHIBITORS: FROM BENCH TO BEDSIDE?.MEDICINAL RESEARCH REVIEWS. VOL. 36. ISSUE 1. P. 92 -118 134 82% 6
9 PRATT, WB , TOFT, DO , (2003) REGULATION OF SIGNALING PROTEIN FUNCTION AND TRAFFICKING BY THE HSP90/HSP70-BASED CHAPERONE MACHINERY.EXPERIMENTAL BIOLOGY AND MEDICINE. VOL. 228. ISSUE 2. P. 111-133 177 61% 908
10 CSERMELY, P , SCHNAIDER, T , SOTI, C , PROHASZKA, Z , NARDAI, G , (1998) THE 90-KDA MOLECULAR CHAPERONE FAMILY: STRUCTURE, FUNCTION, AND CLINICAL APPLICATIONS. A COMPREHENSIVE REVIEW.PHARMACOLOGY & THERAPEUTICS. VOL. 79. ISSUE 2. P. 129 -168 261 54% 621

Classes with closest relation at Level 2


Rank Class id link
1 1816 INTERNATIONAL JOURNAL OF HYPERTHERMIA//HYPERTHERMIA//ISOLATED LIMB PERFUSION
2 990 LENS//CATARACT//ALPHA CRYSTALLIN
3 1548 UNFOLDED PROTEIN RESPONSE//ENDOPLASMIC RETICULUM STRESS//ER STRESS
4 3606 TRIPTOLIDE//CELASTROL//PDCD5
5 1297 RIBOSOME//TRANSLATION TERMINATION//TMRNA
6 892 PROTEIN TRANSLOCATION//PROTEIN IMPORT//SECA
7 3815 CLUSTERIN//APOLIPOPROTEIN J//SULFATED GLYCOPROTEIN 2
8 2956 HEAT STRESS//TEMPERATURE HUMIDITY INDEX//DRY FORAGE INTAKE
9 2159 PIN1//CYCLOPHILIN//CALCINEURIN
10 1328 GLUCOCORTICOID RECEPTOR//ANTIPROGESTIN//JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

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