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KD1500 Physical Biochemistry 7.5 credits

Information per course offering

Termin

Information for Autumn 2024 Start 28 Oct 2024 programme students

Course location

AlbaNova

Duration
28 Oct 2024 - 13 Jan 2025
Periods
P2 (7.5 hp)
Pace of study

50%

Application code

50752

Form of study

Normal Daytime

Language of instruction

Swedish

Course memo
Course memo is not published
Number of places

Places are not limited

Target group
No information inserted
Planned modular schedule
[object Object]

Contact

Examiner
No information inserted
Course coordinator
No information inserted
Teachers
No information inserted
Contact

Mårten Ahlquist, ahlqui@kth.se

Course syllabus as PDF

Please note: all information from the Course syllabus is available on this page in an accessible format.

Course syllabus KD1500 (Autumn 2019–)
Headings with content from the Course syllabus KD1500 (Autumn 2019–) are denoted with an asterisk ( )

Content and learning outcomes

Course contents

The course consists of two parts that deal with biochemical thermodynamics and kinetics in biochemistry.

Biochemical thermodynamics

A living organism is constantly changing: ions are pumped over membranes, signal substances diffuse through the cytoplasm, proteins are built up, formed and broken down, molecules are broken down to give us energy. The driving forces behind these processes can be described based on the laws of thermodynamics. Based on given conditions, the sequence of events can be predicted. In this course, the concepts are described and put into a biological context. The course aims to give the student the opportunity to understand and predict biological and biochemical processes based on basic physical chemistry.

The parts of thermodynamics:

  • The first law of thermodynamics.
  • Internal energy and enthalpy.
  • The second law of thermodynamics.
  • Entropy.
  • Gibb’s free energy.
  • Phase equilibrium and phase transitions, among others for biopolymers and bioaggregates.
  • Chemical balance.
  • Effects of catalysts and of temperature, proton transfers and equilibrium
  • Ion and electron transport.

Kinetics in Biochemistry

Kinetics is the science of the speed of chemical reactions. By studying how quickly an enzyme breaks down a substrate, detailed information about the reaction mechanism can be obtained.

The parts of kinetics:

  • Reakton cross-sections.
  • Reaction laws and mechanisms.
  • Complex biochemical processes.
  • Enzyme catalysis.

Prerequisites equivalent to KD1510 Chemical equilibrium are recommended.

Intended learning outcomes

After completion of the course the student shall have

Knowledge and understanding to:

  • Describe the basic theories of thermodynamics, for example the first and second laws with terms such as internal energy, enthalpy, entropy and Gibb’s free energy.
  • Be able to apply the basic theories to explain driving forces in biological and biochemical systems.
  • Be able to apply kinetic theory to draw conclusions about biochemical processes such as enzymatically catalyzed reactions.

Literature and preparations

Specific prerequisites

BB1150, KD1020

Recommended prerequisites

No information inserted

Equipment

No information inserted

Literature

No information inserted

Examination and completion

If the course is discontinued, students may request to be examined during the following two academic years.

Grading scale

A, B, C, D, E, FX, F

Examination

  • LAB1 - Laboratory Assignment, 1.5 credits, grading scale: P, F
  • TEN1 - Examination 1, 3.0 credits, grading scale: A, B, C, D, E, FX, F
  • TEN2 - Examination 2, 3.0 credits, grading scale: A, B, C, D, E, FX, F

Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

Opportunity to complete the requirements via supplementary examination

No information inserted

Opportunity to raise an approved grade via renewed examination

No information inserted

Examiner

Ethical approach

  • All members of a group are responsible for the group's work.
  • In any assessment, every student shall honestly disclose any help received and sources used.
  • In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.

Further information

Course room in Canvas

Registered students find further information about the implementation of the course in the course room in Canvas. A link to the course room can be found under the tab Studies in the Personal menu at the start of the course.

Offered by

Main field of study

Technology

Education cycle

First cycle

Add-on studies

No information inserted

Contact

Mårten Ahlquist, ahlqui@kth.se

Supplementary information

Course responsible Mårten Ahlquist (ahlqui@kth.se)

Overlaps with the courses KD1040, KD1050, KE1030 and KE1160.