Algorithms for problems such as alignment, phylogeny, sorting by reversals. An introduction to Hidden Markov Models.
DD2450 Algorithmic Bioinformatics 6.0 credits
This course has been discontinued.
Last planned examination: Spring 2017
Decision to discontinue this course:
No information insertedInformation per course offering
Course offerings are missing for current or upcoming semesters.
Course syllabus as PDF
Please note: all information from the Course syllabus is available on this page in an accessible format.
Course syllabus DD2450 (Autumn 2009–)Content and learning outcomes
Course contents
Intended learning outcomes
After successfully taking this course, students will be able to:
- give their own account gene regulation, the central dogma, mutations that affect the genome, and experimental high-throughput techniques,
- implement, describe, and discuss the algorithms treated during the course as well as how they relate to each other,
- apply the fundamental algorithm design methodologies dynamic programming, MCMC, and EM to problems in computational biology and bioinformatics,
- apply, describe, and discuss the modeling principles parsimony, maximum likelihood, and bayesian modelling.
Literature and preparations
Specific prerequisites
Single course students: 90 university credits including 45 university credits in Mathematics or Information Technology. English B or equivalent.
Recommended prerequisites
One of the courses 2D1353/DD1352 Algorithms, Data Structures, and Complexity and DD2354 Algorithms and Complexity or DD2352 Algorithms and Complexity or the equivalent. Contact the instructor to find out if other courses may suffice.
Equipment
Literature
To be announced at least 4 weeks before course start at the web page for the course. Previous year material produced at the department was used.
Examination and completion
If the course is discontinued, students may request to be examined during the following two academic years.
Grading scale
Examination
- ÖVN1 - Exercises, 6.0 credits, grading scale: A, B, C, D, E, FX, F
Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.
The examiner may apply another examination format when re-examining individual students.
In this course all the regulations of the code of honor at the School of Computer science and Communication apply, see: http://www.kth.se/csc/student/hederskodex/1.17237?l=en_UK.
Other requirements for final grade
Written exercises (OVN1; 6 university credits).
Opportunity to complete the requirements via supplementary examination
Opportunity to raise an approved grade via renewed examination
Examiner
Ethical approach
- All members of a group are responsible for the group's work.
- In any assessment, every student shall honestly disclose any help received and sources used.
- In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.
Further information
Course room in Canvas
Offered by
Main field of study
Education cycle
Add-on studies
Please discuss with the instructor.