Tissue and cell biology, histology, extracellular matrix, intercellular communication/growth factors, tissue metabolism, cell signalling, biomarkers, electrophysiology, immunology, microbiology, biocompatibility.
Seminars with industry researchers.
HL2020 Tissue Physiology and Pharmacology 15.0 credits
This course has been discontinued.
Decision to discontinue this course:
No information inserted
Information per course offering
Course offerings are missing for current or upcoming semesters.
Course syllabus as PDF
Please note: all information from the Course syllabus is available on this page in an accessible format.
Course syllabus HL2020 (Autumn 2007–)Headings with content from the Course syllabus HL2020 (Autumn 2007–) are denoted with an asterisk ( )
Content and learning outcomes
Course contents
Intended learning outcomes
The course deals with tissue physiology and pathology as well as the influence of biomaterials (biocompatibility) and the effects of different pharmacological agents.
The student should after completed course be able to:
- Understand the basic physiological and structural properties of human tissues
- Understand basic elements of tissue homeostasis
- Get an insight into tissue adaptation mechanisms
- Understand the basics of regulation of gene expression
- Get an insight into the structure and function of the genome, transcriptome, proteome and physiome
- Understand the basics of inflammation and immunology
- Understand blood coagulation and anti-clotting mechanisms
- Have an insight in tissue reactions to foreign materials and injury
- Understand wound healing and tissue repair
- Get an insight into tissue engineering techniques
- Understand the basics of cell- and gene transfer/therapy
- Get an overview of how medical device electrical stimulators affect different tissues
- Know about the basic methods to assess cell and tissue function (metabolism, signaling, electrophysiology, contractility/force)
- Understand the physiological and disease related relevance and limitations of various biomarkers
- Understand the principles of anatomic positioning of different medical devices
Literature and preparations
Specific prerequisites
Basic knowledge of anatomy, e.g. from the courses HL2006 Medical Engineering, Basic Course and/or HL1010 Systems Biology.
Literature
Biomaterials Science and Biocompatibility, Frederick H. Silver, David L. Christiansen, Springer Verlag, 331 pp, 2005.
Examination and completion
Grading scale
A, B, C, D, E, FX, F
Examination
- PRO1 - Assignments, 5.0 credits, grading scale: P, F
- TEN1 - Examination, 10.0 credits, grading scale: A, B, C, D, E, FX, F
Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.
The examiner may apply another examination format when re-examining individual students.
If the course is discontinued, students may request to be examined during the following two academic years.
Other requirements for final grade
Examination (10 ECTS): Grade A-F
Home assignments, Labs and Project reports (5 ECTS), grade P/F
Examiner
No information inserted
Ethical approach
- All members of a group are responsible for the group's work.
- In any assessment, every student shall honestly disclose any help received and sources used.
- In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.
Further information
Course room in Canvas
Registered students find further information about the implementation of the course in the course room in Canvas. A link to the course room can be found under the tab Studies in the Personal menu at the start of the course.
Offered by
Education cycle
Second cycle