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BB2255 Applied Gene Technology 7.5 credits

The course aims to give detailed insight into the techniques and trends in the fields of genomics and transcriptomics, DNA-assisted proteomics and high throughput data analysis in genomics and transcriptomics. This will build up the necessary foundations for further understanding of association studies, forensics, population genetics, diagnostics, medicine and drug development.

Information per course offering

Termin

Information for Autumn 2024 Start 28 Oct 2024 programme students

Course location

KTH Campus

Duration
28 Oct 2024 - 13 Jan 2025
Periods
P2 (7.5 hp)
Pace of study

50%

Application code

51231

Form of study

Normal Daytime

Language of instruction

English

Course memo
Course memo is not published
Number of places

Places are not limited

Target group
No information inserted
Planned modular schedule
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Contact

Examiner
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Course coordinator
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Teachers
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Course syllabus as PDF

Please note: all information from the Course syllabus is available on this page in an accessible format.

Course syllabus BB2255 (Autumn 2021–Autumn 2024)
Headings with content from the Course syllabus BB2255 (Autumn 2021–Autumn 2024) are denoted with an asterisk ( )

Content and learning outcomes

Course contents

The course aims to give detailed insight into the techniques and trends in the fields of genomics and transcriptomics, DNA-assisted proteomics and high throughput data analysis in genomics and transcriptomics. The focus of the course will thus be on describing, applying and relating state-of-the-art technologies and high throughput data analysis. This will build up the necessary foundations for further understanding of association studies, forensics, population genetics, diagnostics, medicine and drug development.

The course will describe conventional strategies for whole genome sequencing, high throughput methods for typing of genetic variations, advanced techniques and platforms for DNA sequencing including whole genome sequencing, RNA-seq, and single cell transcript profiling.

The course also consists of a series of lectures, and computer-based laboratory exercises, aimed at understanding and analyzing data from genome sequencing, RNA-seq and single cell RNA-seq (scRNA-seq).

In addition, the students are involved in a literature project, which will be performed in groups. Each group presents scientific articles and will oppose other groups’ articles. This project aims to teach critical reading, interpretation and comparison of the most advanced techniques and platforms in the field of high-throughput molecular biology. The project requires teamwork and planning, as well as participation in the groups’ common work. Presence when the project is presented is compulsory.

Intended learning outcomes

On completion of the course, the students should be able to:

  • Describe, illustrate and apply different techniques in the fields of genomics and transcriptomics
  • Describe, illustrate and apply different techniques used for high-throughput molecular biology studies
  • Report orally and in writing within the subject
  • Review and give constructive feedback on the reports within the subject
  • Explain the theory of state-of-the-art tools/algorithms for processing data from high-throughput molecular biology experiments
  • Choose and use appropriate methods and tools for processing data from high-throughput molecular biology experiments

Literature and preparations

Specific prerequisites

A bachelor's degree, corresponding to at least 180 ECTS credits, including at least a total of 20 ECTS Biotechnology, 20 ECTS Chemistry, and 20 ECTS Mathematics,

Recommended prerequisites

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Equipment

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Literature

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Examination and completion

If the course is discontinued, students may request to be examined during the following two academic years.

Grading scale

A, B, C, D, E, FX, F

Examination

  • PRO1 - Literature Seminar, 1.0 credits, grading scale: P, F
  • PRO2 - Computer-based Laboratory exercises, 2.5 credits, grading scale: P, F
  • TEN1 - Written exam, 4.0 credits, grading scale: A, B, C, D, E, FX, F

Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

Opportunity to complete the requirements via supplementary examination

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Opportunity to raise an approved grade via renewed examination

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Examiner

Ethical approach

  • All members of a group are responsible for the group's work.
  • In any assessment, every student shall honestly disclose any help received and sources used.
  • In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.

Further information

Course room in Canvas

Registered students find further information about the implementation of the course in the course room in Canvas. A link to the course room can be found under the tab Studies in the Personal menu at the start of the course.

Offered by

Main field of study

Biotechnology

Education cycle

Second cycle

Add-on studies

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Supplementary information

The module ÖVN1 will not be used.