HL2003 Radiation Physics and Biology 6.0 credits

Strålterapeutisk fysik och biologi

Radiation has for several decades, been used to treat tumours. Different types of radiation such as photons, electrons, neutrons, protons or light ions can be used. The clinically most used treatment modalities are photons and electrons. The course gives a basic knowledge in the physical and biological effects of ionising radiation in tissue and an overview of methods for treatment optimisation to get the best therapy outcome.

  • Education cycle

    Second cycle
  • Main field of study

    Electrical Engineering
  • Grading scale

    A, B, C, D, E, FX, F

Course offerings

Autumn 19 for programme students

Autumn 18 for programme students

Intended learning outcomes

The aim of the course is to give a basic knowledge in radiation physics and biological effects of ionising radiation in order to understand the principles of radiation therapy.

Course main content

Basic interaction processes of ionising radiation with matter. Basic concepts of dosimetry, dosimetric quantities and units. Accelerators for radiation therapy, principles of linear and circular accelerators. Beam transport through treatment head to patient. Optimal design of the therapy beam. Principles of optimal treatment planning. Algorithms for calculations of dose distribution in the patient. Quality control and assurance.
Introduction to biology of the cell. Basic chemical reactions in cells. Lesions produced by radiation in DNA molecules. Cell survival models. Radiation effects on normal tissues and tumours. The biological basis of radiotherapy, oxygen effect, dose rate dependence, dose fractionation.

Eligibility

7E1101 Medical engineering, basic course.

Literature

Lecture material available at the department.

Examination

  • TEN1 - Examinsation, 6.0, grading scale: A, B, C, D, E, FX, F

Requirements for final grade

Written examination and exercises.

Offered by

CBH/Biomedical Engineering and Health Systems

Contact

Emely Kjellsson Lindblom, emely.lindblom@fysik.su.se; Iuliana Toma-Dasu, iuliana.livia.dasu@fysik.su.se

Examiner

Mats Nilsson <spexmats@kth.se>

Add-on studies

5A1414 Radiation Detectors and Medical Imaging systems, 5 p
7E1112 Implants and biomaterials, 4p,
7E1115 Engineering in intensive care and anesthesia, 4p,
7E1113 Medical instrumentation and signal processing, 4p,
7E1110 Quality and regulatory aspects on medical devices, 2p.

Version

Course syllabus valid from: Autumn 2007.
Examination information valid from: Spring 2019.