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CB203V Animal Cell Culture Technology for the Production of Biologics 4.0 credits

Protein drugs or biopharmaceuticals are taking an increasing part among therapeutic drugs world-wide. Furthermore, a large majority of these are produced from animal cell cultivation based processes. This course gives the fundaments of animal cell cultivation for the production of protein drugs in the pharmaceutical industry, and how these processes are developed, for which practical application is given through simulation software.

Information per course offering

Termin

Information for Spring 2025 Start 17 Mar 2025 single courses students

Course location

AlbaNova

Duration
17 Mar 2025 - 2 Jun 2025
Periods
P4 (4.0 hp)
Pace of study

25%

Application code

20042

Form of study

Distance Daytime

Language of instruction

English

Course memo
Course memo is not published
Number of places

5 - 35

Target group
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Planned modular schedule
[object Object]
Schedule
Schedule is not published
Part of programme
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Contact

Examiner
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Course coordinator
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Teachers
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Course syllabus as PDF

Please note: all information from the Course syllabus is available on this page in an accessible format.

Course syllabus CB203V (Spring 2022–)
Headings with content from the Course syllabus CB203V (Spring 2022–) are denoted with an asterisk ( )

Content and learning outcomes

Course contents

The course teaches theory and methodology in the field of cell technology applied to animal cells.

Theoretical concepts included

  • basic techniques for animal cell culture in shake flasks and small-scale bioreactors
  • description and use of stable expression systems (cell lines)
  • overview of animal cell metabolism during cultivation, and its application in process design 
  • aspects concerning commercial production such as patient safety
  • application of knowledge from the course to develop and design culture processes, including aspects of scale-up for industrial application

The student also receives practical training with the support of computer simulation in

  • developing a culture process for industrial application

Intended learning outcomes

After passing the course, the student should be able to:

  • demonstrate knowledge of key theoretical concepts and basic methodology regarding the cultivation process of animal cells
  • demonstrate the ability to use acquired knowledge to design, motivate and present strategies for animal cell culture process in order to manufacture a therapeutic biologics

Literature and preparations

Specific prerequisites

Completed bachelor's degree and/or courses in biochemistry, cell biology or microbiology and chemistry totaling at least 30 credits.

Equipment

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Literature

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Examination and completion

If the course is discontinued, students may request to be examined during the following two academic years.

Grading scale

A, B, C, D, E, FX, F

Examination

  • LAB1 - Laboratory using computer simulation, 2.0 credits, grading scale: A, B, C, D, E, FX, F
  • TEN1 - Written exam, 2.0 credits, grading scale: A, B, C, D, E, FX, F

Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

Opportunity to complete the requirements via supplementary examination

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Opportunity to raise an approved grade via renewed examination

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Examiner

Ethical approach

  • All members of a group are responsible for the group's work.
  • In any assessment, every student shall honestly disclose any help received and sources used.
  • In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.

Further information

Course room in Canvas

Registered students find further information about the implementation of the course in the course room in Canvas. A link to the course room can be found under the tab Studies in the Personal menu at the start of the course.

Offered by

Main field of study

Biotechnology

Education cycle

Second cycle

Add-on studies

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