CB204V Single-cell and spatial transcriptomics data analysis 2.5 credits

The course consists of lectures and computer lab. The lectures focus on theoretical aspects of single-cell and spatial transcriptomic analysis. Computer lab focuses on practical aspects of both subjects. Specific content of the lectures:

• reproducibility of data analysis
• Single-cell analysis workflow
• spatial transcriptomic analysis workflow

After passing the course, the student should be able to:

• assess differences between a single-cell and spatial transcriptomic analysis
• discuss the advantages and disadvantages of both types of analyzes
• perform a general analysis workflow of single-cell and spatial transcriptomic data

A total of 20 university credits (hp) in cell biology, biochemistry, microbiology, gene technology or molecular biology. 6 university credits (hp) in mathematics. English B/6.

If the course is discontinued, students may request to be examined during the following two academic years.

• LAB1 - Working in R, 0.5 credits, grading scale: P, F
• LAB2 - Single-cell analysis, 1.0 credits, grading scale: P, F
• LAB3 - Spatial Transcriptomics analysis, 1.0 credits, grading scale: P, F

Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

Afshin Ahmadian

• All members of a group are responsible for the group's work.
• In any assessment, every student shall honestly disclose any help received and sources used.
• In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.