CB2080 Proteomics 7.5 credits

The lectures are given by experts in their respective fields and cover the background of the proteomic topic, methods for mass spectrometry and affinity-based analyses and their applications in clinical or biological research. The course also includes insights into how proteomics data can be used to map large-scale protein expression and current bioinformatic strategies.

The course activities include a laboratory element where the students practice the methods discussed. The work is performed in a real-world research environment and designed as a group activity ending with project presentations.

At the end of the course, there are two workshops where PhD students, postdocs and researchers present ongoing research projects. The presentations are followed by discussions in groups as well as with the whole class and the students are meant to engage with the presenter about the topic.

The objective of the course is to present current trends for large-scale protein analysis. The course will provide an overview of typical proteomics applications used today, including principles, needs and challenges. The content covers both experimental methods as well as data analysis strategies with a focus on biomarker discovery and precision medicine.

The course will introduce students to current methods, challenges, and applications in the field of proteomics. After completion of the course, the student is able to

1. describe currently applied proteomics technologies
2. compare different proteomics technologies
3. suggest suitable approaches for biomedical applications
4. engage in and contribute to scientific discussions
5. critically evaluate scientific results

A bachelor's degree, corresponding to at least 180 ECTS credits, including at least a total of 20 ECTS in life sciences, 20 ECTS in chemistry, 15 ECTS in mathematics and 5 ECTS in programming.

• ÖVN1 - Exercise, 1.0 credits, grading scale: P, F
• ÖVN2 - Exercise, 1.0 credits, grading scale: P, F
• TEN2 - Oral exam, 5.5 credits, grading scale: A, B, C, D, E, FX, F

Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

If the course is discontinued, students may request to be examined during the following two academic years.

Jochen Schwenk

• All members of a group are responsible for the group's work.
• In any assessment, every student shall honestly disclose any help received and sources used.
• In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.