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FCB3207 Molecular Enzymology for Doctoral Students 4.0 credits

The course provides knowledge and skills in the area of molecular enzymology with a focus on characterizing the kinetic and catalytic mechanisms of enzymes and models for calculating kinetic parameters.

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Headings with content from the Course syllabus FCB3207 (Autumn 2021–) are denoted with an asterisk ( )

Content and learning outcomes

Course contents

The course includes concepts such as enzymes' catalytic principles and reaction mechanisms, pH profiles, binding energies, catalytic processes, activation energy, enzyme kinetics, inhibition, practical enzymology and protein technology.

The course is jointly read with BB2020 but offers in-depth knowledge and additional skills corresponding to the doctoral level through critical analysis of relevant articles in the subject and an individual theoretical project work in molecular enzymology.

Intended learning outcomes

Upon completion of the course, the course participant is expected to be able to

  • demonstrate in-depth knowledge and good analytical ability to explain and analyze complex concepts in enzymology and, based on relevant research literature, communicate the knowledge in writing in a pedagogical way (INL1)
  • demonstrate the ability to select an adequate method, model for data processing and analysis of enzyme kinetics data within the framework of a theoretical project, and to communicate the results in writing in a project report (PRO1)
  • demonstrate the ability to reflect on the importance and possibilities of enzymology for sustainable development (INL1, PRO1)

Course disposition

The course comprises approximately 105 full-time study hours, corresponding to 4,0 ECTS credits. Lectures and exercises are jointly read together with BB2020, but doctoral students perform additional reading tasks that deepen the theoretical knowledge and an independent, research-based theoretical project on molecular enzymology, which provides progression from the second to the third cycle.

The project includes the independent design of a theoretical experiment including the choice of appropriate method and model for data processing and analysis of kinetics data, and to communicate the results in written form.

Literature and preparations

Specific prerequisites

Eligible for studies at the third-cycle level.

Recommended prerequisites

Courses in organic chemistry and / or biochemistry at the second cycle.

Equipment

No information inserted

Literature

Announced at course start.

Examination and completion

If the course is discontinued, students may request to be examined during the following two academic years.

Grading scale

P, F

Examination

  • INL1 - Assignment, 1.0 credits, grading scale: P, F
  • PRO1 - Project, 3.0 credits, grading scale: P, F

Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

Criteria for approved project report and written assignment are given in the course memo.

Other requirements for final grade

For the final grade is required 80% active participation in scheduled lectures and approved hand-in assignments that take the form of reflective and critically examining analysis of selected research articles in the field of molecular enzymology (INL1). Furthermore, the student is required to complete an independent individual project with an approved written project report (PRO1).

Opportunity to complete the requirements via supplementary examination

No information inserted

Opportunity to raise an approved grade via renewed examination

No information inserted

Examiner

Profile picture Per Berglund

Ethical approach

  • All members of a group are responsible for the group's work.
  • In any assessment, every student shall honestly disclose any help received and sources used.
  • In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.

Further information

Course web

Further information about the course can be found on the Course web at the link below. Information on the Course web will later be moved to this site.

Course web FCB3207

Offered by

CBH/Industrial Biotechnology

Main field of study

No information inserted

Education cycle

Third cycle

Add-on studies

No information inserted

Contact

Mats Martinelle

Transitional regulations

If the examination form is changed, the student will be examined according to the examination form that applied when the student was admitted to the course. If the course is completed, the student is given the opportunity to be examined on the course for another two academic years.

Supplementary information

The course replaces F3A5108.

Postgraduate course

Postgraduate courses at CBH/Industrial Biotechnology