FCK3311 NMR Spectroscopy and imaging – basic principles 4.5 credits

The course comprises approximately 100 full-time study hours, whereof 30 hours Zoom lectures, in addition to self-studies. The lectures treat the basic principles such as the origin of the NMR signal, the basic instrumental architecture, principles and praxis of signal treatment, the design and operation of basic pulse sequences, and the molecular origin of the measured NMR parameters.

The vector model of NMR spectroscopy

• rotating frame
• radiofrequency pulses and their effect
• the time dependent signal
• Fourier transformation (FT)
• NMR relaxation
• simple pulse sequences and instrumentation
• the effect of magnetic field gradient
• 2D FT NMR and MRI

After completing the course, the student should be able to

• explain the basic principles for NMR spectroscopy and imaging
• explain how the different NMR parameters depend on and reflect molecular properties.
• use the above listed knowledge to plan, perform and evaluate a laboratory project within the subject area, in group (or individually, depending on the number of participants) including to perform a smaller literature study, and present the laboratory project in a written report and perform an opposition on another laboratory project in the course

Eligible for studies at the third-cycle level.

Understanding NMR Spectroscopy, J. Keeler, 2nd ed.

Distributed material.

If the course is discontinued, students may request to be examined during the following two academic years.

• LAB1 - Laboratory project, 1.5 credits, grading scale: P, F
• RAP1 - Report, 3.0 credits, grading scale: P, F

Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

Approved exam (TEN1; 3 ECTS)

Approved presentation of the laboratory project (LAB1; 1.5 ECTS)

The student should be able to fulfil all parts of the objectives on both a general and basic level, and on a detailed level, and with both width and depth. The student should also be able to use this knowledge to set up NMR experiments to gain insight to particular problems, and relate this to own research.

Istvan Furo

• All members of a group are responsible for the group's work.
• In any assessment, every student shall honestly disclose any help received and sources used.
• In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.

Not more than 30 participants. The course is to a certain extent carried out remotely via Zoom, the lectures (but not the lab) remain open to other participants.