Course contents

Various types of biomaterials for a wide range of biomedical applications. Fundamental structure-property relationships. Basic function and performance of passive and active implant materials. Physical, chemical and mechanical aspects of bulk and surface properties of metallic, polymer and ceramic biomaterials. Principles of surface engineering and combination of different materials. Host-tissue response, blood compatibility, extracellular matrix collagen, bioadhesion, protein adsorption, polymers for controlled drug release. Corrosion and degradation mechanisms of biomaterials in different applications. Selection of biomaterials based on function, biological environments, toxicity and economic aspects. Examples of biomaterials and implant objects and devices. Current research trends and medical device regulation.

Intended learning outcomes

After completion of the course the student will be able to:

• Give examples of biomedical material applications, identify material properties that are critical for metallic, polymer
  and ceramic biomaterials, and suggest proper type of biomaterial for given applications.
• Explain basic physical, chemical and mechanical processes that may occur on biomaterials in use, including corrosion
  and degradation reactions that occur for different biomaterials and their consequences.
• Practically perform testing and property evaluations of common biomedical materials.
• Present and evaluate a project and laboratory assignments orally and in writing.

Course Disposition

No information inserted

Specific prerequisites

At least 150 credits from grades 1, 2 and 3 of which at least 110 credits from years 1 and 2, and bachelor's work must be completed, within a programme that includes:
75 university credits (hp) in chemistry or chemical engineering, 20 university credits (hp) in mathematics and 6 university credits (hp) in computer science or corresponding.

Recommended prerequisites

Basic courses in materials science and engineering.

Equipment

No information inserted

Literature

Selected chapters in “Biomaterials Science, An Introduction to Materials in Medicine", edited by B.D. Ratner, A.S. Hoffman, F.J. Schoen, J.E. Lemons. 2nd edition, Academic Press (2004).

Other lecture materials.

If the course is discontinued, students may request to be examined during the following two academic years.

Grading scale

A, B, C, D, E, FX, F

Examination

• SEM1 - Project, 3,0 hp, betygsskala: P, F
• TEN1 - Written exam, 4,5 hp, betygsskala: A, B, C, D, E, FX, F

Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

Laboratory Work: Report and seminar

Other requirements for final grade

Examination, 4,5 credits,
Lab (report and seminar), 3 credits

Opportunity to complete the requirements via supplementary examination

No information inserted

Opportunity to raise an approved grade via renewed examination

No information inserted

Examiner

Jinshan Pan

Ethical approach

• All members of a group are responsible for the group's work.
• In any assessment, every student shall honestly disclose any help received and sources used.
• In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.

Course web

Further information about the course can be found on the Course web at the link below. Information on the Course web will later be moved to this site.

Offered by

CBH/Chemistry

Main field of study

Biotechnology, Chemical Science and Engineering, Chemistry and Chemical Engineering

Education cycle

Second cycle

Add-on studies

No information inserted