KD2390 Selective Organic Synthesis 9.0 credits

Selektiv organisk syntes

Advanced course in synthetic organic chemistry with emphasis on selective synthesis.

The course includes a theoretical part, which is identical to the course KD2385 Selecive Organic Synthesis, theory, and a laboratory part.

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Offering and execution

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Course information

Content and learning outcomes

Course contents *

  • Fundamental concepts in chemo-, regio-, and stereoselectivity
  • Synthetic strategy and principles for selective, in particular stereoselective, chemical transformations
  • Transition metal catalysis
  • Frontier orbital-controlled reactions
  • Retrosynthetic analysis
  • Advanced organic synthesis

Intended learning outcomes *

After passing the course the student should be able to:

  • Explain basic chemo-, regio-, and stereoselective concepts and apply these in synthesis, as well as construct reactions pathways of complex organic compounds using retrosynthetic analysis.
  • Apply synthesis methodology to perform advanced organic synthesis.

Course Disposition

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Literature and preparations

Specific prerequisites *

At least 150 credits from grades 1, 2 and 3 of which at least 110 credits from years 1 and 2, and bachelor's work must be completed, within a programme that includes:

75 university credits (hp) in chemistry or chemical engineering, 20 university credits (hp) in mathematics and 9 university credits (hp) in computer science or corresponding.

Recommended prerequisites

1st cycle courses in organic chemistry (e.g., KD1090/KD1230 and KD1100/KD1270), and 2nd cycle course in organic chemistry KD2310 (can be studied in parallel), or equivalent courses.

Equipment

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Literature

Clayden, Greeves and Warren Organic Chemistry, Oxford University Press, 2012 (ISBN 978-0-19-927029-3)and hand-out material

Examination and completion

Grading scale *

A, B, C, D, E, FX, F

Examination *

  • LAB1 - Laboratory Work, 2.5 credits, Grading scale: P, F
  • TEN1 - Examination, 6.5 credits, Grading scale: A, B, C, D, E, FX, F

Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

Other requirements for final grade *

The final grade will be the same as for the examination

Opportunity to complete the requirements via supplementary examination

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Opportunity to raise an approved grade via renewed examination

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Examiner

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Further information

Course web

Further information about the course can be found on the Course web at the link below. Information on the Course web will later be moved to this site.

Course web KD2390

Offered by

CBH/Chemistry

Main field of study *

Chemical Science and Engineering

Education cycle *

Second cycle

Add-on studies

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Ethical approach *

  • All members of a group are responsible for the group's work.
  • In any assessment, every student shall honestly disclose any help received and sources used.
  • In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.

Supplementary information

The course KD2390 includes a theoretical part, which is identical to the course KD2385 Selecive Organic Synthesis, theory.
Only one of the courses above can be included in the diploma.