- Fundamental concepts in chemo-, regio-, and stereoselectivity
- Synthetic strategy and principles for selective, in particular stereoselective, chemical transformations
- Transition metal catalysis
- Frontier orbital-controlled reactions
- Retrosynthetic analysis
- Advanced organic synthesis
Intended learning outcomes *
After the course the student should be able to:
- describe basic chemo-, regio- and stereochemical concepts
- describe principles for selective synthesis, in particular for stereoselective synthesis
- explain the selectivity observed in chemical reactions
- sugest methods for selective synthesis of simple organic compounds, also containing stereogenic elements
- identify suitable reagents for selective transformations
- use retrosynthetic analysis for the construction of synthetic routes for simple organic compounds
- prepare organic compounds using advanced synthetic methodology
Lectures, classroom exercises, workshop and laboratory work.
Literature and preparations
Specific prerequisites *
Admission requirements for programme students at KTH: At least 150 credits from grades 1, 2 and 3 of which at least 110 credits from years 1 and 2, and bachelor's work must be completed, within a programme that includes: 75 university credits (hp) in chemistry or chemical engineering, 20 university credits (hp) in mathematics and 6 university credits (hp) in computer science or corresponding.
Admission requirements for independent students: 75 university credits (hp) in chemistry or chemical engineering, 20 university credits (hp) in mathematics and 6 university credits (hp) in computer science or corresponding. Documented proficiency in English corresponding to English B.
1st cycle courses in organic chemistry (e.g., KD1090/KD1230 and KD1100/KD1270), and 2nd cycle course in organic chemistry KD2310 (can be studied in parallel), or equivalent courses.
No information inserted
Clayden, Greeves and Warren Organic Chemistry, Oxford University Press, 2012 (ISBN 978-0-19-927029-3)and hand-out material
Examination and completion
Grading scale *
A, B, C, D, E, FX, F
Grading scale: P, F
Grading scale: A, B, C, D, E, FX, F
Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.
The examiner may apply another examination format when re-examining individual students.
Other requirements for final grade *
Examination (TEN1; 6,5 credits) Laboratory Work (LAB1; 2,5 credits)
The final grade will be the same as for the examination
Opportunity to complete the requirements via supplementary examination
No information inserted
Opportunity to raise an approved grade via renewed examination