Course contents *
The course aims to give detailed insight into the techniques and trends in the fields of genomics and transcriptomics, DNA-assisted proteomics and high throughput data analysis in genomics and transcriptomics. The focus of the course will thus be on describing, applying and relating state-of-the-art technologies and high throughput data analysis. This will build up the necessary foundations for further understanding of association studies, forensics, population genetics, diagnostics, medicine and drug development.
The course will describe conventional strategies for whole genome sequencing, high throughput methods for typing of genetic variations, advanced techniques and platforms for DNA sequencing including whole genome sequencing, RNA-seq, and single cell transcript profiling.
The course also consists of a series of lectures, and computer-based laboratory exercises, aimed at understanding and analyzing data from genome sequencing, RNA-seq and single cell RNA-seq (scRNA-seq).
In addition, the students are involved in a literature project, which will be performed in groups. Each group presents scientific articles and will oppose other groups’ articles. This project aims to teach critical reading, interpretation and comparison of the most advanced techniques and platforms in the field of high-throughput molecular biology. The project requires teamwork and planning, as well as participation in the groups’ common work. Presence when the project is presented is compulsory.