Advanced Organic Chemistry (KD2310, 7.5 credits) builds on basic courses in organic chemistry (e.g., KTH courses Organic Chemistry 1 (KD1230) and Organic Chemistry 2 (KD1270), and is preparative for further studies in organic chemistry (e.g., KTH course Selective Organic Synthesis (CE2385, KD2390).
If you have read the course earlier and want to re-register on the course, please contact the course expedition and they will assist you. Teachers CANNOT register students or give access to Canvas.
Markus Kärkäs (Course coordinator & examiner)
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Content and learning outcomes
Short course description:
- Focus on reactivity and synthesis in organic chemistry.
- Principles and factors governing reactions of organic compounds.
- Application of the concept of green chemistry in organic chemistry for sustainable development.
- The process of drug development in the pharmaceutical industry.
- Application of organic chemistry in medicinal and pharmaceutical chemistry.
Detailed course description:
- Delineate mechanisms for reactions in organic chemistry.
- Application of organic reactions in multi-step synthesis.
- The process of drug discovery in the pharmaceutical industry.
- Principles concerning green- and sustainable chemistry.
- Principles regarding reaction energetics and reaction kinetics.
- Application of molecular orbital theory on reactivity and stereochemistry.
- Principles for the rationalization of regio- or enantioselective reaction outcomes.
- Silicon, phosphorous, and sulfur in organic chemistry.
- Basic metal-organic chemistry.
- Application of knowledge in organic chemistry on pharmaceutical and medicinal chemistry.
Intended learning outcomes
After completion of the course the student will be able to:
- Describe, explain, and compare the reactivity in organic chemistry and synthesis with for example reaction mechanisms and concepts in physical organic chemistry.
- Analyze and evaluate processes in organic chemistry from a green and sustainable perspective.
Literature and preparations
Bachelor's degree in engineering or in sciences including 75 credits in chemistry or chemical engineering of which at least 10 credits in organic chemistry. English B/6.
Clayden, Greeves, Warren: Organic Chemistry, Oxford University Press, Oxford, UK, 2012, ISBN 978-0-19-927029-3
Examination and completion
If the course is discontinued, students may request to be examined during the following two academic years.
- PRO1 - Project, 1.5 credits, grading scale: A, B, C, D, E, FX, F
- TEN1 - Written exam, 6.0 credits, grading scale: P, F
Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.
The examiner may apply another examination format when re-examining individual students.
The final grade will be the same as the grade obtained on the written exam (TEN1)
Opportunity to complete the requirements via supplementary examination
Opportunity to raise an approved grade via renewed examination
The ability to raise your grade (plussning) is not allowed.
- All members of a group are responsible for the group's work.
- In any assessment, every student shall honestly disclose any help received and sources used.
- In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.
Further information about the course can be found on the Course web at the link below. Information on the Course web will later be moved to this site.Course web CK2310
Main field of study
Selective Organic Synthesis (CE2385 or KD2390).
The course has the same content as the course KD2310 Advanced Organic Chemistry 7,5 hp.
Only one of the courses CK2310 and KD2310 may be included in the exam.