HL2003 Radiation Physics and Biology 6.0 credits

Strålterapeutisk fysik och biologi

Radiation has for several decades, been used to treat tumours. Different types of radiation such as photons, electrons, neutrons, protons or light ions can be used. The clinically most used treatment modalities are photons and electrons. The course gives a basic knowledge in the physical and biological effects of ionising radiation in tissue and an overview of methods for treatment optimisation to get the best therapy outcome.

Show course information based on the chosen semester and course offering:

Offering and execution

No offering selected

Select the semester and course offering above to get information from the correct course syllabus and course offering.

Course information

Content and learning outcomes

Course contents *

Basic interaction processes of ionising radiation with matter. Basic concepts of dosimetry, dosimetric quantities and units. Accelerators for radiation therapy, principles of linear and circular accelerators. Beam transport through treatment head to patient. Optimal design of the therapy beam. Principles of optimal treatment planning. Algorithms for calculations of dose distribution in the patient. Quality control and assurance.
Introduction to biology of the cell. Basic chemical reactions in cells. Lesions produced by radiation in DNA molecules. Cell survival models. Radiation effects on normal tissues and tumours. The biological basis of radiotherapy, oxygen effect, dose rate dependence, dose fractionation.

Intended learning outcomes *

The aim of the course is to give a basic knowledge in radiation physics and biological effects of ionising radiation in order to understand the principles of radiation therapy.

Course Disposition

No information inserted

Literature and preparations

Specific prerequisites *

7E1101 Medical engineering, basic course.

Recommended prerequisites

No information inserted

Equipment

No information inserted

Literature

Meddelas vid kursstart.
Föreläsningskompendier som delas ut i samband med föreläsningarna.

Finns att köpa på institutionen vid kursstart.

Examination and completion

Grading scale *

A, B, C, D, E, FX, F

Examination *

  • TEN1 - Examinsation, 6.0 credits, Grading scale: A, B, C, D, E, FX, F

Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

Other requirements for final grade *

Written examination and exercises.

Opportunity to complete the requirements via supplementary examination

No information inserted

Opportunity to raise an approved grade via renewed examination

No information inserted

Examiner

Mats Nilsson

Further information

Course web

Further information about the course can be found on the Course web at the link below. Information on the Course web will later be moved to this site.

Course web HL2003

Offered by

CBH/Biomedical Engineering and Health Systems

Main field of study *

Electrical Engineering

Education cycle *

Second cycle

Add-on studies

5A1414 Radiation Detectors and Medical Imaging systems, 5 p
7E1112 Implants and biomaterials, 4p,
7E1115 Engineering in intensive care and anesthesia, 4p,
7E1113 Medical instrumentation and signal processing, 4p,
7E1110 Quality and regulatory aspects on medical devices, 2p.

Contact

Emely Kjellsson Lindblom, emely.lindblom@fysik.su.se; Iuliana Toma-Dasu, iuliana.livia.dasu@fysik.su.se

Ethical approach *

  • All members of a group are responsible for the group's work.
  • In any assessment, every student shall honestly disclose any help received and sources used.
  • In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.