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KD2310 Advanced Organic Chemistry 7.5 credits

Administer About course

Advanced Organic Chemistry (KD2310, 7.5 credits) builds on basic courses in organic chemistry (e.g., KTH courses Organic Chemistry 1 (KD1230) and Organic Chemistry 2 (KD1270), and is preparative for further studies in organic chemistry (e.g., KTH course Selective Organic Synthesis (CE2385, KD2390).

The course uses Canvas as a Learning Management System and in order to access Canvas you have to register for the course. If you study the course for the first time, register on the web.

If you have read the course earlier and want to re-register on the course, please contact the course expedition and they will assist you. Teachers CANNOT register students or give access to Canvas.

Note that from HT2023 the course KD2310 will be replaced with the course CK2310.

Markus Kärkäs (Course coordinator & examiner)
Email: karkas@kth.se

Course offerings are missing for current or upcoming semesters.
Headings with content from the Course syllabus KD2310 (Autumn 2023–) are denoted with an asterisk ( )

Content and learning outcomes

Course contents

Short course description:

  • Focus on reactivity and synthesis in organic chemistry.
  • Principles and factors governing reactions of organic compounds.
  • Application of the concept of green chemistry in organic chemistry for sustainable development.
  • The process of drug development in the pharmaceutical industry.
  • Application of organic chemistry in medicinal and pharmaceutical chemistry.

Detailed course description:

  • Delineate mechanisms for reactions in organic chemistry. 
  • Application of organic reactions in multi-step synthesis.
  • The process of drug discovery in the pharmaceutical industry. 
  • Principles concerning green- and sustainable chemistry. 
  • Principles regarding reaction energetics and reaction kinetics. 
  • Application of molecular orbital theory on reactivity and stereochemistry.
  • Principles for the rationalization of regio- or enantioselective reaction outcomes. 
  • Silicon, phosphorous, and sulfur in organic chemistry. 
  • Basic metal-organic chemistry.
  • Application of knowledge in organic chemistry on pharmaceutical and medicinal chemistry.

Intended learning outcomes

After completion of the course the student will be able to:

  • Describe, explain, and compare the reactivity in organic chemistry and synthesis with for example reaction mechanisms and concepts in physical organic chemistry. 
  • Analyze and evaluate processes in organic chemistry from a green and sustainable perspective.

Literature and preparations

Specific prerequisites

At least 150 credits from grades 1, 2 and 3 of which at least 110 credits from years 1 and 2, and bachelor's work must be completed, within a programme that includes:
75 university credits (hp) in chemistry or chemical engineering, 20 university credits (hp) in mathematics and 6 university credits (hp) in computer science or corresponding.

The course KD1270 Organic Chemistry, Basic Concepts and Practice 2 or equivalent knowledge.

Recommended prerequisites

No information inserted

Equipment

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Literature

Clayden, Greeves & Warren, Organic Chemistry, Oxford University Press, Oxford, UK, 2012, ISBN: 978-0-19-927029-3

Examination and completion

If the course is discontinued, students may request to be examined during the following two academic years.

Grading scale

A, B, C, D, E, FX, F

Examination

  • PRO1 - Project, 1.5 credits, grading scale: P, F
  • TEN2 - Written exam, 6.0 credits, grading scale: A, B, C, D, E, FX, F

Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

Other requirements for final grade

The final grade will be the same as for the examination

Opportunity to complete the requirements via supplementary examination

No information inserted

Opportunity to raise an approved grade via renewed examination

No information inserted

Examiner

Profile picture Markus Kärkäs

Ethical approach

  • All members of a group are responsible for the group's work.
  • In any assessment, every student shall honestly disclose any help received and sources used.
  • In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.

Further information

Course room in Canvas

Registered students find further information about the implementation of the course in the course room in Canvas. A link to the course room can be found under the tab Studies in the Personal menu at the start of the course.

Offered by

CBH/Chemistry

Main field of study

Chemical Science and Engineering, Chemistry and Chemical Engineering

Education cycle

Second cycle

Add-on studies

Selective Organic Synthesis (KD2390)