KD2310 Advanced Organic Chemistry 7.5 credits

Organisk kemi, fortsättningskurs

Advanced Organic Chemistry (KD2310, 7.5 credits) builds on basic courses in organic chemistry (e.g., KTH courses Organic Chemistry 1 (KD1230) and Organic Chemistry 2 (KD1270), and is preparative for further studies in organic chemistry (e.g., KTH course Selective Organic Synthesis (KD2385, KD2390).

The course uses Canvas as a Learning Management System and in order to access Canvas you have to register for the course. If you study the course for the first time, register on the web.

If you have read the course earlier and want to re-register on the course, please contact the course expedition and they will assist you. Teachers can NOT register students or give access to Canvas.

Markus Kärkäs (Course responsible, examinator)
Email: karkas@kth.se

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Course information

Content and learning outcomes

Course contents *

Short course description:

  • Focus on reactivity and synthesis in organic chemistry.
  • Principles and factors governing reactions of organic compounds.
  • Application of the concept of green chemistry in organic chemistry for sustainable development.
  • The process of drug development in the pharmaceutical industry.
  • Application of organic chemistry in medicinal and pharmaceutical chemistry.

Detailed course description:

  • Delineate mechanisms for reactions in organic chemistry. 
  • Application of organic reactions in multi-step synthesis.
  • The process of drug discovery in the pharmaceutical industry. 
  • Principles concerning green- and sustainable chemistry. 
  • Principles regarding reaction energetics and reaction kinetics. 
  • Application of molecular orbital theory on reactivity and stereochemistry.
  • Principles for the rationalization of regio- or enantioselective reaction outcomes. 
  • Silicon, phosphorous, and sulfur in organic chemistry. 
  • Basic metal-organic chemistry.
  • Application of knowledge in organic chemistry on pharmaceutical and medicinal chemistry.

Intended learning outcomes *

After completion of the course the student will be able to:

  • Describe, explain, and compare the reactivity in organic chemistry and synthesis with for example reaction mechanisms and concepts in physical organic chemistry. 
  • Analyze and evaluate processes in organic chemistry from a green and sustainable perspective.

Course Disposition

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Literature and preparations

Specific prerequisites *

At least 150 credits from grades 1, 2 and 3 of which at least 110 credits from years 1 and 2, and bachelor's work must be completed, within a programme that includes:
75 university credits (hp) in chemistry or chemical engineering, 20 university credits (hp) in mathematics and 6 university credits (hp) in computer science or corresponding.

The course KD1270 Organic Chemistry, Basic Concepts and Practice 2 or equivalent knowledge.

Recommended prerequisites

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Equipment

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Literature

Clayden, Greeves & Warren, Organic Chemistry, Oxford University Press, Oxford, UK, 2012, ISBN: 978-0-19-927029-3

Examination and completion

Grading scale *

A, B, C, D, E, FX, F

Examination *

  • PRO1 - Project, 1.5 credits, Grading scale: P, F
  • TEN2 - Examination, 6.0 credits, Grading scale: A, B, C, D, E, FX, F

Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

Other requirements for final grade *

The final grade will be the same as for the examination

Opportunity to complete the requirements via supplementary examination

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Opportunity to raise an approved grade via renewed examination

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Examiner

Markus Kärkäs

Further information

Course web

Further information about the course can be found on the Course web at the link below. Information on the Course web will later be moved to this site.

Course web KD2310

Offered by

CBH/Chemistry

Main field of study *

Chemical Science and Engineering, Chemistry and Chemical Engineering

Education cycle *

Second cycle

Add-on studies

Selective Organic Synthesis (KD2390)

Ethical approach *

  • All members of a group are responsible for the group's work.
  • In any assessment, every student shall honestly disclose any help received and sources used.
  • In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.

Supplementary information

The course has the same content as the course KD2190 Organic Chemistry, Theory, Advanced Course 1.

Only one of the courses KD2310 and KD2190 may be included in the exam.