Publications

 

Ina Schuppe Koistinen Publication List

Peer-reviewed papers in scientific journals

 

 

1. SCHWIELER L, SAMUELSSON M, FRYE MA, BHAT M, SCHUPPE-KOISTINEN I, JUNGHOLM O, JOHANSSON AG, LANDEN M, SELLGREN CM, ERHARDT S. Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients. Journal of neuroinflammation 2016 13;1 51-

JIF(2014) 5.41

doi:10.1186/s12974-016-0517-7

 

1. Eakins R, Walsh J, Randle L, Jenkins RE, Schuppe-Koistinen I, Rowe C, Lewis PS, Vasieva O, Prats N, Brillant N, Auli M, Bayliss M, Webb S, Rees JA, Kitteringham NR, Goldring CE, Park BK. Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome. SCIENTIFIC REPORTS 2015 5;

JIF(2014) 5.58

doi:10.1038/srep16423

 

1. SCHWIELER L, LARSSON MK, SKOGH E, KEGEL ME, ORHAN F, ABDELMOATY S, FINN A, BHAT M, SAMUELSSON M, LUNDBERG K, DAHL ML, SELLGREN C, SCHUPPE-KOISTINEN I, SVENSSON C, ERHARDT S, ENGBERG G. Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia--significance for activation of the kynurenine pathway. Journal of psychiatry & neuroscience : JPN 2015 40;2 126-33

JIF(2014) 5.86

Times cited 10

doi:10.1503/jpn.140126

 

1. Agudelo LZ, Femenia T, Orhan F, Porsmyr-Palmertz M, Goiny M, Martinez-Redondo V, Correia JC, Izadi M, Bhat M, Schuppe-Koistinen I, Pettersson A, Ferreira DMS, Krook A, Barres R, Zierath JR, Erhardt S, Lindskog M, Ruas JL. Skeletal Muscle PGC-1 alpha 1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression (vol 159, pg 33, 2014). CELL 2015 160;1-2 351-351

JIF(2014) 32.24

doi:10.1016/j.cell.2014.12.025

 

1. YIMER G, GRY M, AMOGNE W, MAKONNEN E, HABTEWOLD A, PETROS Z, ADERAYE G, SCHUPPE-KOISTINEN I, LINDQUIST L, AKLILLU E. Evaluation of patterns of liver toxicity in patients on antiretroviral and anti-tuberculosis drugs: a prospective four arm observational study in ethiopian patients. PloS one 2014 9;4 e94271-

JIF(2014) 3.23

Times cited 2

doi:10.1371/journal.pone.0094271

 

1. KEGEL ME, BHAT M, SKOGH E, SAMUELSSON M, LUNDBERG K, DAHL ML, SELLGREN C, SCHWIELER L, ENGBERG G, SCHUPPE-KOISTINEN I, ERHARDT S. Imbalanced kynurenine pathway in schizophrenia. International journal of tryptophan research : IJTR 2014 7; 15-22

doi:10.4137/IJTR.S16800

 

1. Thulin P, Nordahl G, Gry M, Yimer G, Aklillu E, Makonnen E, Aderaye G, Lindquist L, Mattsson CM, Ekblom B, Antoine DJ, Park BK, Linder S, Harrill AH, Watkins PB, Glinghammar B, Schuppe-Koistinen I. Keratin-18 and microRNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts. LIVER INTERNATIONAL 2014 34;3 367-378

JIF(2014) 4.85

Times cited 8

doi:10.1111/liv.12322

 

1. AGUDELO LZ, FEMENIA T, ORHAN F, PORSMYR-PALMERTZ M, GOINY M, MARTINEZ-REDONDO V, CORREIA JC, IZADI M, BHAT M, SCHUPPE-KOISTINEN I, PETTERSSON AT, FERREIRA DM, KROOK A, BARRES R, ZIERATH JR, ERHARDT S, LINDSKOG M, RUAS JL. Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression. Cell 2014 159;1 33-45

JIF(2014) 32.24

Times cited 48

doi:10.1016/j.cell.2014.07.051

 

1. Mattes WB, Kamp HG, Fabian E, Herold M, Krennrich G, Looser R, Mellert W, Prokoudine A, Strauss V, van Ravenzwaay B, Walk T, Naraoka H, Omura K, Schuppe-Koistinen I, Nadanaciva S, Bush ED, Moeller N, Ruiz-Noppinger P, Piccoli SP. Prediction of Clinically Relevant Safety Signals of Nephrotoxicity through Plasma Metabolite Profiling. BIOMED RESEARCH INTERNATIONAL 2013 ;

JIF(2014) 1.58

Times cited 1

doi:10.1155/2013/202497

 

1. RAFTER I, GRABERG T, KOTRONEN A, STROMMER L, MATTSON CM, KIM RW, EHRENBORG E, ANDERSSON HB, YKI-JARVINEN H, SCHUPPE-KOISTINEN I, EKBLOM B, COTGREAVE I, GLINGHAMMAR B. Isoform-specific alanine aminotransferase measurement can distinguish             hepatic from extrahepatic injury in humans. International journal of molecular medicine 2012 30;5 1241-9

JIF(2014) 2.09

Times cited 8

doi:10.3892/ijmm.2012.1106

 

1. SAFE-T Consortium, DILI-GHPS Grp, M'Kada H, Perazzo H, Munteanu M, Ngo Y, Ramanujam N, Fautrel B, Imbert-Bismut F, Ratziu V, Schuppe-Koistinen I, Leblond V, Delattre JY, Samson Y, Caen OL, Bricaire F, Khayat D, Pierrot-Deseilligny C, Herson S, Amoura Z, Tilleul P, Deckmyn O, Coriat P, Delpech VN, Boulogne P, Bonnefont-Rousselot D, Poynard T. Real Time Identification of Drug-Induced Liver Injury (DILI) through Daily Screening of ALT Results: A Prospective Pilot Cohort Study. PLOS ONE 2012 7;8

JIF(2014) 3.23

Times cited 6

doi:10.1371/journal.pone.0042418

 

1. Boekelheide K, Schuppe-Koistinen I. SOT/EUROTOX Debate: Biomarkers From Blood and Urine Will Replace Traditional Histopathological Evaluation to Determine Adverse Responses. TOXICOLOGICAL SCIENCES 2012 129;2 249-255

JIF(2014) 3.85

Times cited 1

doi:10.1093/toxsci/kfs200

 

1. Faulkner L, Martinsson K, Santoyo-Castelazo A, Cederbrant K, Schuppe-Koistinen I, Powell H, Tugwood J, Naisbitt DJ, Park BK. The Development of In Vitro Culture Methods to Characterize Primary T-Cell Responses to Drugs. TOXICOLOGICAL SCIENCES 2012 127;1 150-158

JIF(2014) 3.85

Times cited 18

doi:10.1093/toxsci/kfs080

 

1. Matheis K, Laurie D, Andriamandroso C, Arber N, Badimon L, Benain X, Bendjama K, Clavier I, Colman P, Firat H, Goepfert J, Hall S, Joos T, Kraus S, Kretschmer A, Merz M, Padro T, Planatscher H, Rossi A, Schneiderhan-Marra N, Schuppe-Koistinen I, Thomann P, Vidal JM, Molac B. A generic operational strategy to qualify translational safety biomarkers. DRUG DISCOVERY TODAY 2011 16;13-14 600-608

JIF(2014) 6.69

Times cited 23

doi:10.1016/j.drudis.2011.04.011

 

1. Neiman M, Hedberg JJ, Donnes PR, Schuppe-Koistinen I, Hanschke S, Schindler R, Uhlen M, Schwenk JM, Nilsson P. Plasma Profiling Reveals Human Fibulin-1 as Candidate Marker for Renal Impairment. JOURNAL OF PROTEOME RESEARCH 2011 10;11 4925-4934

JIF(2014) 4.25

Times cited 11

doi:10.1021/pr200286c

 

1. DILI Grp SAFE-T Consortium, M'Kada H, Munteanu M, Perazzo H, Ngo Y, Ramanujam N, Imbert-Bismut F, Ratziu V, Bonnefont-Rousselot D, Souberbielle B, Schuppe-Koistinen I, Poynard T. What are the best reference values for a normal serum alanine transaminase activity (ALT)? Impact on the presumed prevalence of drug induced liver injury (DILI). REGULATORY TOXICOLOGY AND PHARMACOLOGY 2011 60;3 290-295

JIF(2014) 2.03

Times cited 15

doi:10.1016/j.yrtph.2011.04.002

 

1. Sourial S, Searchfield L, Schuppe-Koistinen I, Betton GR, Riccardi D, Price SA. Application of Dolichos biflorus in immunoassay detection of kidney collecting duct biomarkers. BIOMARKERS 2010 15;5 424-435

JIF(2014) 2.26

Times cited 6

doi:10.3109/1354750X.2010.483526

 

1. Chetty RK, Ozer JS, Lanevschi A, Schuppe-Koistinen I, McHale D, Pears JS, Vonderscher J, Sistare FD, Dieterle F. A Systematic Approach to Preclinical and Clinical Safety Biomarker Qualification Incorporating Bradford Hill's Principles of Causality Association. CLINICAL PHARMACOLOGY & THERAPEUTICS 2010 88;2 260-262

JIF(2014) 7.9

Times cited 4

doi:10.1038/clpt.2010.77

 

1. Alm E, Torgrip RJO, Aberg KM, Schuppe-Koistinen I, Lindberg J. Time-resolved biomarker discovery in H-1-NMR data using generalized fuzzy Hough transform alignment and parallel factor analysis. ANALYTICAL AND BIOANALYTICAL CHEMISTRY 2010 396;5 1681-1689

JIF(2014) 3.44

Times cited 4

doi:10.1007/s00216-009-3421-5

 

1. Alm E, Torgrip RJO, Aberg KM, Schuppe-Koistinen I, Lindberg J. A solution to the 1D NMR alignment problem using an extended generalized fuzzy Hough transform and mode support. ANALYTICAL AND BIOANALYTICAL CHEMISTRY 2009 395;1 213-223

JIF(2014) 3.44

Times cited 16

doi:10.1007/s00216-009-2940-4

 

1. Andersson U, Lindberg J, Wang SH, Balasubramanian R, Marcusson-Stahl M, Hannula M, Zeng CH, Juhasz PJ, Kolmert J, Backstrom J, Nord L, Nilsson K, Martin S, Glinghammar B, Cederbrant K, Schuppe-Koistinen I. A systems biology approach to understanding elevated serum alanine transaminase levels in a clinical trial with ximelagatran. BIOMARKERS 2009 14;8 572-586

JIF(2014) 2.26

Times cited 20

doi:10.3109/13547500903261354

 

1. BUTURA A, NILSSON K, MORGAN K, MORGAN TR, FRENCH SW, JOHANSSON I, SCHUPPE-KOISTINEN I, INGELMAN-SUNDBERG M. The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model. Journal of hepatology 2009 50;3 572-83

JIF(2014) 11.34

Times cited 30

doi:10.1016/j.jhep.2008.10.020

 

1. Torgrip RJO, Aberg KM, Alm E, Schuppe-Koistinen I, Lindberg J. A note on normalization of biofluid 1D H-1-NMR data. METABOLOMICS 2008 4;2 114-121

JIF(2014) 3.86

Times cited 31

doi:10.1007/s11306-007-0102-2

 

1. Adourian A, Jennings E, Balasubramanian R, Hines WM, Damian D, Plasterer TN, Clish CB, Stroobant P, McBurney R, Verheij ER, Bobeldijk I, Van der Greef J, Lindberg J, Kenne K, Andersson U, Hellmold H, Nilsson K, Salter H, Schuppe-Koistinen I. Correlation network analysis for data integration and biomarker selection. MOLECULAR BIOSYSTEMS 2008 4;3 249-259

JIF(2014) 3.21

Times cited 32

doi:10.1039/b708489g

 

1. Aberg KM, Torgrip RJO, Kolmert J, Schuppe-Koistinen I, Lindberg J. Feature detection and alignment of hyphenated chromatographic-mass spectrometric data - Extraction of pure ion chromatograms using Kalman tracking. JOURNAL OF CHROMATOGRAPHY A 2008 1192;1 139-146

JIF(2014) 4.17

Times cited 25

doi:10.1016/j.chroma.2008.03.033

 

1. Skordi E, Yap IKS, Claus SP, Martin FPJ, Cloarec O, Lindberg J, Schuppe-Koistinen I, Holmes E, Nicholson JK. Analysis of time-related metabolic fluctuations induced by ethionine in the rat. JOURNAL OF PROTEOME RESEARCH 2007 6;12 4572-4581

JIF(2014) 4.25

Times cited 30

doi:10.1021/pr070268q

 

1. Csenki L, Alm E, Torgrip RJO, Aberg KM, Nord LI, Schuppe-Koistinen I, Lindberg J. Proof of principle of a generalized fuzzy Hough transform approach to peak alignment of one-dimensional H-1 NMR data. ANALYTICAL AND BIOANALYTICAL CHEMISTRY 2007 389;3 875-885

JIF(2014) 3.44

Times cited 21

doi:10.1007/s00216-007-1475-9

 

1. Thysell E, Pohjanen E, Lindberg J, Schuppe-Koistinen I, Moritz T, Jonsson P, Anttii H. Reliable profile detection in comparative metabolomics. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY 2007 11;2 209-224

JIF(2014) 2.36

Times cited 9

doi:10.1089/omi.2007.0006

 

1. Griffin JL, Nicholls AW, Daykin CA, Heald S, Keun HC, Schuppe-Koistinen I, Griffiths JR, Cheng LL, Rocca-Serra P, Rubtsov DV, Robertson D. Standard reporting requirements for biological samples in metabolomics experiments: mammalian/in vivo experiments. METABOLOMICS 2007 3;3 179-188

JIF(2014) 3.86

Times cited 22

doi:10.1007/s11306-007-0077-z

 

1. Jonsson P, Stenlund H, Moritz T, Trygg J, Sjostrom M, Verheij ER, Lindberg J, Schuppe-Koistinen I, Antti H. A strategy for modelling dynamic responses in metabolic samples characterized by GC/MS. METABOLOMICS 2006 2;3 135-143

JIF(2014) 3.86

Times cited 19

doi:10.1007/s11306-006-0027-1

 

1. Torgrip RJO, Lindberg J, Linder M, Karlberg B, Jacobsson SP, Kolmert J, Gustafsson I, Schuppe-Koistinen I. New modes of data partitioning based on PARS peak alignment for improved multivariate biomarker/biopattern detection in H-1-NMR spectroscopic metabolic profiling of urine. METABOLOMICS 2006 2;1 1-19

JIF(2014) 3.86

Times cited 13

doi:10.1007/s11306-005-0013-z

 

1. Jonsson P, Johansson ES, Wuolikainen A, Lindberg J, Schuppe-Koistinen I, Kusano M, Sjostrom M, Trygg J, Moritz T, Antti H. Predictive metabolite profiling applying hierarchical multivariate curve resolution to GC-MS datas - A potential tool for multi-parametric diagnosis. JOURNAL OF PROTEOME RESEARCH 2006 5;6 1407-1414

JIF(2014) 4.25

Times cited 63

doi:10.1021/pr0600071

 

1. Stolt R, Torgrip RJO, Lindberg J, Csenki L, Kolmert J, Schuppe-Koistinen I, Jacobsson SP. Second-order peak detection for multicomponent high-resolution LC/MS data. ANALYTICAL CHEMISTRY 2006 78;4 975-983

JIF(2014) 5.64

Times cited 24

doi:10.1021/ac050980b

 

1. Pohjanen E, Thysell E, Lindberg J, Schuppe-Koistinen I, Moritz T, Jonsson P, Antti H. Statistical multivariate metabolite profiling for aiding biomarker pattern detection and mechanistic interpretations in GC/MS based metabolomics. METABOLOMICS 2006 2;4 257-268

JIF(2014) 3.86

Times cited 12

doi:10.1007/s11306-006-0032-4

 

1. IDBORG H, ZAMANI L, EDLUND PO, SCHUPPE-KOISTINEN I, JACOBSSON SP. Metabolic fingerprinting of rat urine by LC/MS Part 1. Analysis by hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005 828;1-2 9-13

JIF(2014) 2.73

Times cited 107

doi:10.1016/j.jchromb.2005.07.031

 

1. IDBORG H, ZAMANI L, EDLUND PO, SCHUPPE-KOISTINEN I, JACOBSSON SP. Metabolic fingerprinting of rat urine by LC/MS Part 2. Data pretreatment methods for handling of complex data. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005 828;1-2 14-20

JIF(2014) 2.73

Times cited 63

doi:10.1016/j.jchromb.2005.07.049

 

1. Stand Metab Reporting Struct worki, Lindon JC, Nicholson JK, Holmes E, Keun HC, Craig A, Pearce JTM, Bruce SJ, Hardy N, Sansone SA, Antti H, Jonsson P, Daykin C, Navarange M, Beger RD, Verheij ER, Amberg A, Baunsgaard D, Cantor GH, Lehman-McKeeman L, Earll M, Wold S, Johansson E, Haselden JN, Kramer K, Thomas C, Lindberg J, Schuppe-Koistinen I, Wilson ID, Reily MD, Robertson DG, Senn H, Krotzky A, Kochhar S, Powell J, van der Ouderaa F, Plumb R, Schaefer H, Spraul M. Summary recommendations for standardization and reporting of metabolic analyses. NATURE BIOTECHNOLOGY 2005 23;7 833-838

JIF(2014) 41.51

Times cited 140

doi:10.1038/nbt0705-833

 

1. BUTURA A, JOHANSSON I, NILSSON K, WARNGARD L, INGELMAN-SUNDBERG M, SCHUPPE-KOISTINEN I. Differentiation of human hepatoma cells during confluence as revealed by gene expression profiling. Biochemical pharmacology 2004 67;7 1249-58

JIF(2014) 5.01

Times cited 15

doi:10.1016/j.bcp.2003.10.033

 

1. FRANZEN B, DUVEFELT K, JONSSON C, ENGELHARDT B, OTTERVALD J, WICKMAN M, YANG Y, SCHUPPE-KOISTINEN I. Gene and protein expression profiling of human cerebral endothelial cells activated with tumor necrosis factor-alpha. Brain research. Molecular brain research 2003 115;2 130-46

JIF(2005) 1.59

Times cited 40

doi:10.1016/S0169-328X(03)00185-2

 

1. Forshed J, Schuppe-Koistinen I, Jacobsson SP. Peak alignment of NMR signals by means of a genetic algorithm. ANALYTICA CHIMICA ACTA 2003 487;2 189-199

JIF(2014) 4.51

Times cited 130

doi:10.1016/S0003-2670(03)00570-1

 

1. IDBORG-BJORKMAN H, EDLUND PO, KVALHEIM OM, SCHUPPE-KOISTINEN I, JACOBSSON SP. Screening of biomarkers in rat urine using LC/electrospray ionization-MS and two-way data analysis. Analytical chemistry 2003 75;18 4784-92

JIF(2014) 5.64

Times cited 122

doi:10.1021/ac0341618

 

1. Hellmold H, Nilsson CB, Schuppe-Koistinen I, Kenne K, Warngard L. Identification of end points relevant to detection of potentially adverse drug reactions. TOXICOLOGY LETTERS 2002 127;1-3 239-243

JIF(2014) 3.26

Times cited 10

 

1. LIND C, GERDES R, HAMNELL Y, SCHUPPE-KOISTINEN I, VON LOWENHIELM HB, HOLMGREN A, COTGREAVE IA. Identification of S-glutathionylated cellular proteins during oxidative stress and constitutive metabolism by affinity purification and proteomic analysis. Archives of biochemistry and biophysics 2002 406;2 229-40

JIF(2014) 3.02

Times cited 192

 

1. Schuppe-Koistinen I, Frisk AL, Janzon L. Molecular profiling of hepatotoxicity induced by a aminoguanidine carboxylate in the rat: gene expression profiling. TOXICOLOGY 2002 179;3 197-219

JIF(2014) 3.62

Times cited 6

 

1. COTGREAVE IA, GERDES R, SCHUPPE-KOISTINEN I, LIND C. S-glutathionylation of glyceraldehyde-3-phosphate dehydrogenase: role of thiol oxidation and catalysis by glutaredoxin. Methods in enzymology 2002 348; 175-82

JIF(2002) 1.69

Times cited 52

 

1. Schuppe-Koistinen I. Molecular profiling and prediction of toxicity. ATLA-ALTERNATIVES TO LABORATORY ANIMALS 2001 29;3 287-289

JIF(2014) 1.59

 

1. LIND C, GERDES R, SCHUPPE-KOISTINEN I, COTGREAVE IA. Studies on the mechanism of oxidative modification of human glyceraldehyde-3-phosphate dehydrogenase by glutathione: catalysis by glutaredoxin. Biochemical and biophysical research communications 1998 247;2 481-6

JIF(2014) 2.3

Times cited 85

 

 

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