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Thesis
PHD THESIS
- Developed and implemented a new statistical convergence assessment and burn-in estimation technique based on Estimated Sample Size (ESS) for multiple Markov chain Monte Carlo parameters for phylogenetic tree.
- Developed software “VMCMC”, a visualization and statistical tool for Markov chain Monte Carlo analysis of phylogenetic trees.
- Designed and implemented a synteny based algorithm “GenFamClust” that quantifies gene synteny and combines it with protein similarity to infer gene homology.
- Compared and validated the accuracy, cluster size, similarity and differences between GenFamClust and other homology inference algorithms using Chordatic, Fungi and simulated datasets.
- Applied “GenFamClust” algorithm on a large dataset consisting of whole genome species and inferred gene families and synteny conservation. The results are available in the database “GenFam”.
- Determining the relationship between age and the degree of a gene class network graph.
- Extended the original work to determine the relationship for pathway class graph as well.
- Worked on a new notion of gene class and pathway class graphs.
- Lip Synchronization with Speech signal, a mixture of many different domains of Computer Science.
- Reflects my command of diverse Computer Science fields such as Digital Signal Processing, Computer Graphics, Artificial Intelligence and Artificial Neural Networks.