Sandra Garcia Gallego
About me
Email:
Phone: 087908070
Funding
Marie Sklodowska-Curie Individual Fellowships.
Research interests
Development of dendritic macromolecules for biomedical applications.
Educational background
· 2013 - International Ph.D. in Chemistry – University of Alcalá (Spain). Qualification: with Honors (Cum Laude).
· 2013 - M.S. Teacher training in High School Education – National University of Distant Education (Spain).
· 2009 - M.S. Therapeutic Targets: Research and Development – University of Alcalá (Spain).
· 2008 - B.S. Chemistry (Specialization: Medical Chemistry) – University of Alcalá (Spain). Qualification: with Honors.
Personal information
Born in 1985 in Guadalajara (Spain). Personal awards:
· 2013 - Appointed as "30 under 30" by Scientific American Magazine and nominated as "Forbes 30 under 30 in Science and Medicine" by Forbes Magazine.
· 2013 - Post-Doctoral Fellow, funding Knut and Alice Wallenberg Foundation.
· 2013 - European Comission Fellow in the 63rd Lindau Nobel Laureate Meeting in Chemistry.
· 2009 - Special award for B.S. Chemistry (best marks), from University of Alcala.
· 2008 - Master Fellow, funding LaCaixa Fundación Obra Social.
· 2004-2006 - Grants of Excellence, funding Comunidad de Madrid.
Publications
Research Articles
2015 S. García-Gallego, L. Díaz, J. L. Jiménez, R. Gómez, F. J. De la Mata, M. A. Muñoz-Fernández. HIV-1 antiviral behavior of anionic PPI metallo-dendrimers with EDA core. Eur. J. Med. Chem. 98, 139-148. DOI: 10.1016/j.ejmech.2015.05.026
2015 S. García-Gallego, D. Hult, J. V. Olsson, M. Malkoch. Fluoride-promoted esterification with imidazolide-activated compounds: A modular and sustainable approach to dendrimers. Angew. Chem. Int. Ed. 54(8), 2416-2419. DOI: 10.1002/anie.201411370
2014 J. V. Olsson, D. Hult, Y. Cai, S. García-Gallego, M. Malkoch. Reactive imidazole intermediates: simplified synthetic approach to functional aliphatic cyclic carbonates. Polym. Chem. 5, 6651-6655. DOI: 10.1039/c4py00911h
2013 S. García-Gallego, M. Cangiotti, L. Fiorani, A. Fattori, M. A. Muñoz-Fernández, R. Gómez, M. F. Ottaviani, F. J. de la Mata. Anionic sulfonated and carboxylated PPI dendrimers with EDA core: synthesis and characterization as selective metal complexing agents. Dalton Trans. 42(16), 5874-5889. DOI: 10.1039/c3dt32870h
2013 I. Heredero-Bermejo, J. L. Copa-Patiño, J. Soliveri, S. García-Gallego, B. Rasines, R. Gómez, F. J. de la Mata, J. Pérez-Serrano. In vitro evaluation of the effectiveness of new water-stable cationic carbosilane dendrimers against Acanthamoeba castellanii UAH-T17c3 trophozoites. Parasitol. Res. 112(3), 961-969. DOI: 10.1007/s00436-012-3216-z
2012 M. Galán, J. Sánchez-Rodríguez, M. Cangiotti, S. García-Gallego, J. L. Jiménez, R. Gómez, M. F. Ottaviani, M. A. Muñoz-Fernández, F. J. de la Mata. Antiviral properties against HIV of water soluble copper carbosilane dendrimers and their EPR characterization. Curr. Med. Chem. 19(29), 4984-4994. DOI: 10.2174/0929867311209024984
2012 N. de las Cuevas, S. García-Gallego, B. Rasines, F. J. de la Mata, L. G. Guijarro, M. A. Muñoz-Fernández, R. Gómez. In Vitro studies of water-stable cationic carbosilane dendrimers as delivery vehicles for gene therapy against HIV and Hepatocarcinoma. Curr. Med. Chem. 19(29), 5052-5061. DOI: 10.2174/0929867311209025052
2012 S. García-Gallego, J. Sánchez Rodríguez, J. L. Jiménez, M. Cangiotti, M. F. Ottaviani, M. A. Muñoz-Fernández, R. Gómez, F. J. de la Mata. Polyanionic N-donor ligands as chelating agents in transition metal complexes: synthesis, structural characterization and antiviral properties against HIV. Dalton Trans. 41(21), 6488-6499. DOI: 10.1039/c2dt11793b
2011 E. Arnaiz, L. I. Doucede, S. García-Gallego, K. Urbiola, R. Gómez, C. Tros de Ilarduya, F. J. de la Mata. Synthesis of cationic carbosilane dendrimers via Click Chemistry and their use as effective carriers for DNA transfection into cancerous cells. Mol. Pharm. 9(3), 433-447. DOI: 10.1021/mp200542j
2011 S. García-Gallego, M. J. Serramía, E. Arnaiz, L. Díaz, M. A. Muñoz-Fernández, M. P. Gómez-Sal, R. Gómez, F. J. de la Mata. Transition metal complexes based on a sulfonated-containing N-donor ligand as inhibitors of HIV replication. Eur. J. Inorg. Chem. 10, 1657-1665. DOI: 10.1002/ejic.201001121
Patents
2011 J. de la Mata, R. Gómez, S. García-Gallego, E. Arnaiz, J. L. Copa, J. Soliveri, J. M. Hernández, C. Tros de Ilarduya, M. J. Serramía, M. A. Muñoz-Fernández, V. Briz. Dendrímeros carbosilano catiónicos obtenidos mediante Click-chemistry, su preparación y sus usos. Spanish Patent ES2392994 (B1).
Reviews & Book Chapters
2015 S. García-Gallego, M. Malkoch. Dendritic polyester scaffolds: Functional and biocompatible precision polymers for durg delivery applications. In Polymeric Drug Delivery Techniques - Translating Polymer Science for Drug Delivery. Aldrich Materials Science.
2015 S. García-Gallego, A. Nyström, M. Malkoch. Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications. Prog. Polym. Sci. 48, 85-110. DOI: 10.1016/j.progpolymsci.2015.04.006
2014 S. García-Gallego; G. J. L. Bernardes. Carbon-Monoxide-releasing molecules for the delivery of therapeutic CO In Vivo. Angew. Chem. Int. Ed. 53(37), 9712-9721. DOI: 10.1002/anie.201311225
2013 M. F. Ottaviani; D. Appelhans; F. J. De la Mata; S. García-Gallego; A. Fattori; C. Coppola; M. Cangiotti; L. Fiorani; J. P. Majoral; A.-M. Caminade; M. Bryszewska; D. K. Smith; N. Garti; B. Klajnert. Characterization of dendrimers and their interactions with biomolecules for medical use by means of Electron Magnetic Resonance. In Dendrimers in Biomedical Applications. 115-133. RSC Publishing, DOI: 10.1039/9781849737296-00115