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Version skapad av Magnus Andersson 2014-12-08 15:08
Extra material
We have a separate page with extra non-public reading material available at www.tcblab.org/outgoing/proteinphysics. You can e-mail Magnus Andersson to get the password if you are registered on the course, or ask during class. The rest of that site is currently under production...
- Lecture 1: Monday Jan 20, 4-6pm, Room FE21
Introduction, proteins, amino acids. Chapters 1 & 2 of the book. slides
The review by David Eisenberg - it's a good read - and will facilitate your understanding of protein secondary structure - optional though. 2003_Review
- Lecture 2: Tuesday Jan 21, 4-6pm, Room FE21
Molecular interactions (chapters 3-4). slides
Cyrus Levinthals paper in Scientific American on protein structure & folding - good introduction - but optional for this course. Levinthal
- Lecture 3: Monday Jan 27, 3-5pm, Room FE21
Thermodynamics, defining hydrophobic effect from free energies, electrostatics (chapter 5-6). slides
- Lecture 4: Thursday Jan 30, 3-5pm, Room FB41
Secondary structure (chapters 7,10). Note that we cover chapters 8 & 9 later! slides
- Lecture 5: Monday Feb 3, 3-5pm, Room FE21
Statistical mechanics, the partition function, phase transitions & a-helix formation (chapter 8 & 9 (to p. 109)). slides
- Lecture 6: Thursday February 6, 3-5pm, Room FE21
Protein secondary structure formation and free energy (rest of chapter 9). slides
- Lecture 7: Wednesday February 12, 1-3pm, Room FA31
Fibrous proteins and globular proteins with alpha-helix and beta-sheet structure (chapter 11, 13 & 14). slides
- Lecture 8: Thursday February 13, 8-10am, Room FE21
Membranes & membrane proteins (chapter 12, but we will deviate a lot from the book). slides
- Lecture 9: Friday February 21, 3-5pm, Room FE21
Protein folds (chapter 15-16). slides
- Lecture 10:Monday February 24, 3-5pm, Room FE21
Denaturation & the character of transitions - cooperativity or not (chapter 17-18). slides
- Lecture 11:Wednesday Feb 26, 3-5pm, Room FE21
Kinetics of protein foldning (chapters 19-21). slides
- Lecture 12:Friday Feb 28, 3-5pm, Room FE21
Prediction and design of protein structure, bioinformatics (chapters 22-23). slides
- Lecture 13:Monday March 3, 3-5pm, Room FE21
GPCRs, docking and drug design (chapters 24-25, deviate a lot from the book). slides
- Lecture 14:Friday March 11, 3-5pm, Room FB51
Course repetition. slides